Major League Soccer (MLS) is a professional soccer league in the United States and Canada, but it is not considered one of the major professional sports leagues in North America.

The National Football League (NFL) has the highest annual revenue among all professional sports leagues in North America, with revenue exceeding $15 billion in recent years.

The Dallas Cowboys (NFL) have the highest valuation among all professional sports teams in the world, with a valuation estimated to be over $6 billion.

Lionel Messi (Soccer) has the highest annual salary among all professional sports players in the world, with a salary exceeding $100 million per year.

The National Football League (NFL) has the most lucrative television contracts among all professional sports leagues in North America, with contracts worth billions of dollars per year.

The National Basketball Association (NBA) has the most global reach among all professional sports leagues in North America, with games broadcast in over 200 countries and territories worldwide.

Major League Soccer (MLS) has the most diverse fan base among all professional sports leagues in North America, with fans from a wide range of ethnic and cultural backgrounds.

The National Basketball Association (NBA) has the most female fans among all professional sports leagues in North America, with women making up over 40% of the league's fan base.

The National Football League (NFL) has the most social media followers among all professional sports leagues in North America, with over 100 million followers across various platforms.

The National Football League (NFL) has the most merchandise sales among all professional sports leagues in North America, with fans spending billions of dollars on NFL-branded merchandise each year.

The National Football League (NFL) has the most charitable contributions among all professional sports leagues in North America, with teams and players donating millions of dollars to various charities each year.

The National Football League (NFL) has the most political influence among all professional sports leagues in North America, with teams and players often voicing their opinions on political issues and endorsing political candidates.

The National Football League (NFL) has the most economic impact among all professional sports leagues in North America, with the league generating billions of dollars in revenue and supporting millions of jobs.

The National Football League (NFL) has the most cultural impact among all professional sports leagues in North America, with the league's games and players often featured in popular culture and influencing fashion, music, and other aspects of American life.