0

Therapeutic action of different classes of drugs - class-XII

Description: therapeutic action of different classes of drugs
Number of Questions: 91
Created by:
Tags: chemistry in everyday life chemistry in daily life applied chemistry chemistry
Attempted 0/90 Correct 0 Score 0

What is tincture of iodine?

  1. 2-3% solution of iodine in alcohol-water mixture.

  2. A mixture of iodine in chloroxylenol.

  3. A mixture of 0.2% phenol and 2-3% iodine in water.

  4. 2-3% solution of iodine in potassium iodide.


Correct Option: A
Explanation:

2-3% solution of iodine in alcohol-water mixture is known as tincture of iodine. It is a powerful antiseptic.

Which of the following statements is not correct?

  1. Antiseptics can be safely applied to the living tissues.

  2. Antiseptics can be incorporated into deodorants, face powders and soaps.

  3. Disinfectants can also be applied to the skin safely.

  4. A very dilute solution of a few disinfectants can be used as antiseptics.


Correct Option: C
Explanation:

Disinfectants are harmful to the living tissues hence they are not applied to the skin.

Antiseptic chloroxylenol is:

  1. $4$ - chloro $3, 5 $ - dimethylphenol

  2. $3$ - chloro $3, 5 $ - dimethylphenol

  3. $4$ - chloro $2, 5 $ - dimethylphenol

  4. $5$ - chloro $3, 4 $ - dimethylphenol


Correct Option: A
Explanation:

Chloroxylenol also known as para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and cleaning surgical instruments. Its chemical names are given as 4-Chloro-3,5-dimethylphenol.

The formulation of dettol contains:

  1. chloroxylenol

  2. terpineol

  3. Isopropyl alcohol

  4. all of these.


Correct Option: D
Explanation:

Dettol contains Chloroxylenol (comprises of 4.8% of dettol's total admixture) which is an antiseptic and disinfectant used for skin disinfection and cleaning surgical instruments, Terpineol which is a monoterpene alcohol that has been isolated from variety of sources such as cajuput oil, pine oil, and petotgrain oil. and isopropyl alcohol.

A drug which is effective in curing malaria is:

  1. aspirin.

  2. quinine.

  3. morphine.

  4. analgin.


Correct Option: B
Explanation:
  • An antimicrobial tends to destroy/prevent development or inhibit the pathogenic action of microbes such as bacteria (antibacterial drugs), fungi (antifungal agents), virus (antiviral agents), or other parasites (antiparasitic drugs) selectively.
  • Malaria is a viral disease and caused by female anopheles mosquito. The drugs which are used to cure malaria are quinine,,Hydroxychloroquine Mefloquine etc.

Which of the following can be used as an analgesic without causing addiction?

  1. Morphine

  2. Aspirin

  3. Heroin

  4. Codeine


Correct Option: B
Explanation:
Analgesics reduce or abolish pain without causing impairment of
consciousness, mental confusion, incoordination or paralysis or some
other disturbances of nervous system
Aspirin and paracetamol belong to the class of non-narcotic (non-addictive) analgesics. Aspirin inhibits the synthesis of chemicals known as prostaglandins which stimulate inflammation in the tissue and cause pain. These drugs are effective in relieving skeletal pain such as that due to arthritis. These drugs have many other effects such as reducing fever (antipyretic) and preventing platelet coagulation. Because of its anti blood clotting action, aspirin finds use in prevention of heart attacks.
Morphine,Heroin,Codeine belongs to narcotic(addictive) analgesics.

Which of the following antibiotics is bactericidal?

  1. Erythromycin

  2. Tetracycline

  3. Penicillin

  4. Chloramphenicol


Correct Option: C
Explanation:
  • An antibiotic refers to a substance produced wholly or partly by chemical synthesis, which in low concentrations inhibits the growth or destroys microorganisms by intervening in their metabolic processes.
  • Antibiotics have either cidal (killing) effect or a static (inhibitory) effect on microbes.
  • Bactericidal-Penicillin,Aminoglycosides,Ofloxacin
  • Bacteriostatic-Erythromycin,Tetracycline,Chloramphenicol
  • Ampicillin and Amoxycillin are synthetic modifications of penicillins. These have broad spectrum. It is absolutely essential to test the patients for sensitivity (allergy) to penicillin before it is administered

Antiseptic are the chemical which either ___orthe growth of microorganisms and are applied to the ___.

  1. kill, prevent, living tissues

  2. kill, prevent, non-living objects

  3. increase, decrease, living tissues

  4. kill, increase, non-living tissues


Correct Option: A
Explanation:
  • Antiseptics are applied to the living tissues such as wounds, cuts, ulcers and diseased skin surfaces.
  • Antiseptics helps to kill or prevent the growth of microorganisms.
  • Examples are furacine, soframicine, etc. 
  • Commonly used antiseptic, dettol is a mixture of chloroxylenol and terpineol. Bithionol (the compound is also called bithional) is added to soaps to impart antiseptic properties. Iodine is a powerful antiseptic. 
  • Its 2-3 per cent solution in alcoholwater mixture is known as tincture of iodine. It is applied on wounds. 
  • Iodoform is also used as an antiseptic for wounds. 
  • Boric acid in dilute aqueous solution is weak antiseptic for eyes.

Which of the following is not true about antifertility drugs? 

  1. Birth control pills contain a mixture of synthetic estrogen and progesterone derivatives.

  2. Both compounds i.e.estrogen and progesterone are vitamins.

  3. Progesterone is supposed to suppress ovulation.

  4. Norethindrone is an example of synthetic progesterone derivative.


Correct Option: B
Explanation:

Estrogen and progesterone are hormones.

The main constituents of dettol are:

  1. chloramphenicol and  glycerol

  2. 2-3% solution of iodine in alcohol

  3. 0.2% solution of phenol

  4. chloroxylenol and terpineol


Correct Option: D
Explanation:
Antiseptics are applied to the living tissues such as wounds, cuts, ulcers and diseased skin surfaces. Examples are furacine, soframicine etc. These are not ingested like antibiotics. Commonly used antiseptic, dettol is a mixture of chloroxylenol and terpineol.

Which of the following statements is not correct about penicillin?

  1. Penicillin G has a narrow spectrum.

  2. It is extracted from antibacterial fungus Penicillium.

  3. Ampicillin and amoxycillin are synthetic modifications of penicillins.

  4. It has bacteriostatic effect.


Correct Option: D
Explanation:
  • The real revolution in antibacterial therapy began with the discovery of Alexander Fleming in 1929, of the antibacterial properties of a Penicillium fungus. It is extracted from antibacterial fungus Penicillium.
  • Penicillin G has a narrow spectrum. Ampicillin and Amoxycillin are synthetic modifications of penicillins. These have broad spectrum. It is absolutely essential to test the patients for sensitivity (allergy) to penicillin before it is administered.
  • Antibiotics have either cidal (killing) effect or a static (inhibitory) effect on microbes. Penicillin has Bactericidal effect.

Which statement about aspirin is not true?

  1. Aspirin belongs to narcotic analgesics.

  2. It is effective in relieving pain.

  3. It has antiblood clotting action.

  4. It is neurologically active drug.


Correct Option: A
Explanation:
Aspirin belong to the class of non-narcotic analgesics. Aspirin inhibits the synthesis of chemicals known as prostaglandins which stimulate inflammation in the tissue and cause pain. It is effective in relieving skeletal pain such as that due to arthritis. It has many other effects such as reducing fever (antipyretic) and preventing platelet coagulation. Because of its anti blood clotting action, aspirin finds use in prevention of heart attacks. Aspirin is a neurologically active drug.

Which of the following statements is not correct?

  1. Some antiseptics can be added to soaps.

  2. Dilute solutions of some disinfectants can be used as antiseptic.

  3. Disinfectants are antimicrobial drugs.

  4. Antiseptic medicines can be ingested.


Correct Option: D
Explanation:
  • Antiseptics are applied to the living tissues such as wounds, cuts, ulcers and diseased skin surfaces. These are not ingested like antibiotics.
  • Bithionol (also called bithional) is added to soaps to impart antiseptic properties.
  • Disinfectants are antimicrobial drugs which are applied to inanimate objects such as floors, drainage system, instruments, etc.
  • Same substances can act as an antiseptic as well as a disinfectant by varying the concentration. For example, 0.2 per cent solution of phenol is an antiseptic while its one per cent solution is disinfectant.
  • Hence, option D is the wrong option.

    Which of the following is an example of a broad spectrum antibiotic?

    1. Penicillin G

    2. Chloramphenicol

    3. Streptomycin

    4. Ampicillin


    Correct Option: B,C,D
    Explanation:

    Since, Chloramphenicol functions by inhibiting bacterial protein synthesis, the drug chloramphenicol has a very broad spectrum of activity. It is active against gram-positive bacteria (including most strains of MRSA), gram-negative bacteria and anaerobes.

    Which of the following is an insecticide?

    1. Aspirin

    2. Lindane

    3. DDT

    4. Both B and C


    Correct Option: D
    Explanation:

    DDT (dichlorodiphenyltrichloroethane) is an organo chlorine insecticide, which is a colourless, crystalline solid, tasteless and almost odorless chemical compound. 

    Lindane is an organochlorine chemical variant of hexachlorocyclohexane, used as agricultural insecticide. 

    Among the following statements, which one is not correct?

    1. Aspirin is both an analgesic and an antipyretic.

    2. Ampicillin is a natural antibiotic.

    3. Sulphadiazine is a synthetic antibacterial.

    4. Some disinfectants can be used as antiseptics

      at low concentration.


    Correct Option: B
    Explanation:

    Ampicillin is a beta-lactum antibiotic that is part of the amino penicillin family and is roughly equivalent to its successor, amoxicillin in terms of spectrum and level of activity. It is not a natural antibiotic.

    The class of drugs used for the treatment of cut or wound is:

    1. tranquilizers

    2. antiseptics

    3. antihistamins

    4. antipyretic


    Correct Option: B
    Explanation:

    Antiseptics are applied to the living tissues such as wounds, cuts, ulcers and diseased skin surfaces.

    Which of the following are synthetic antimicrobial chemicals, consumed by humans?

    1. Insulin

    2. Sulphadiazine

    3. Hydrochloric acid

    4. Penicillin


    Correct Option: B,D
    Explanation:

    Sulphadiazine and penicillin are the synthetic antimicrobial chemicals consumed by humans. Insulin and hydrochloric acid are produced by the body.

    It is found in such as which cause cholera and typhoid ?

    1. Nutrients

    2. Bacteria

    3. Inorganic impurities

    4. Other microbes


    Correct Option: B
    Explanation:

    Cholera is caused by vibriocholerae bacteria and typhoid is caused by salmonella typhi bacteria.

    So, diseases like cholera and typhoid is caused by bacteria.

    Which of the following is used as antiseptic?

    1. Tincture of iodine

    2. Equanil

    3. Heroin

    4. Histamine


    Correct Option: A
    Explanation:

    Antiseptics are antimicrobials applied to the living tissues such as wounds, cuts, ulcers and diseased skin surfaces.
    Tincture of iodine is used as antiseptic on wounds.
    Equanil is a tranquilizer.
    Histamine is a antacid.
    Heroin is a analgesic.

    The first anti-microbial to be discovered is:

    1. Soframicin

    2. Pencillin

    3. Oflaxacin

    4. Terpineol


    Correct Option: B
    Explanation:

    An antimicrobial tends to destroy/prevent development of microbes such as bacteria, fungi, virus, or other parasites selectively, and inhibit their pathogenic actions. 
    Alexander Fleming was the first to discover a natural antimicrobial fungus known as Penicillium rubens. The substance he extracted from the fungus was named Penicillin. 

    Which of the following is an antiseptic?

    1. Penicillin

    2. Aminoglycosides

    3. Ofloxacin

    4. Soframicin


    Correct Option: D
    Explanation:

    Anti-microbials are classified as:
    1. Anti-biotics
    2. Antiseptics
    3. Disinfectants
    Antiseptics are anti-microbials which are applied to the living tissues such as wounds, cuts, ulcers and diseased skin surfaces.
    Soframicin is an antiseptic.
    All the other compounds given are antibiotics.

    What was the idea of Paul Ehrlich?

    1. Chemicals which would adversely affect the invading bacteria but not the host, can be used for the treatment of diseases caused by the bacteria.

    2. Chemicals which would adversely affect the invading bacteria but not the host, cannot be used for the treatment of diseases caused by the bacteria.

    3. Chemicals which would adversely affect the invading bacteria but not the guest, can be used for the treatment of diseases caused by the bacteria.

    4. Chemicals which would adversely affect the invading bacteria also the guest, can be used for the treatment of diseases caused by the bacteria.


    Correct Option: A
    Explanation:

    Following was the idea of Paul Ehrlich.
    Chemicals which would adversely affect the invading bacteria but not the host, can be used for the treatment of diseases caused by the bacteria.
    Paul Ehrlich was a German Bacteriologist. He prepared compounds containing arsenic for treating syphilis. In 1908, he got the Nobel Prize for discovering arsphenamine (salvarsan) to kill syphilis bacteria.
    He also worked on azo dyes containing $-N=N-$ linkage similar to $-As=As-$ linkage in salvarsan, and prepared antibiotic protonsil.

    The drug which is used to cure diseases caused by microbes or microorganisms is called as an:

    1. antibiotic

    2. antimicrobial

    3. antifungal

    4. none of these


    Correct Option: B
    Explanation:

    The drug which is used to cure diseases caused by microbes or microorganisms is called as an antimicrobial. Microorganisms like fungi, bacteria and virus cause variety of diseases in human beings. Antimicrobials kill or stop the growth of these microorganisms.

    Salvarsan is the medicine used for which disease?

    1. Maleria

    2. Syphilis

    3. Acidity

    4. all of these


    Correct Option: B
    Explanation:

    Salvarsan is the medicine used for Syphilis. It is also called arsphenamine.
    It was the first antibacterial, discovered by Paul Ehrlich (a German Bacteriologist). In 1908, he got the Nobel Prize for discovering arsphenamine (Salvarsan).

    Antimicrobials are effective on which kind of organisms?

    1. Bacteria

    2. Viruses

    3. Fungi

    4. all of these


    Correct Option: D
    Explanation:

    Antimicrobials are effective on all bacteria, viruses and fungi.
    Microorganisms like fungi, bacteria and virus causes variety of diseases in human beings. Antimicrobials kill or stop the growth of these microorganisms.

    In which year Paul Ehrlich got the Noble Prize for medicine?

    1. 1980

    2. 1908

    3. 1907

    4. 1478


    Correct Option: B
    Explanation:

    In the year 1908, Paul Ehrlich (a German Bacteriologist) got the Noble Prize for medicine for discovering arsphenamine (Salvarsan). It was the first antibacterial discovered by Paul Ehrlich, used for the cure of Syphilis.

    Paul Ehrlich promoted which activity in chemists?

    1. Studying the relationship between structure and metabolism.

    2. Studying the relationship between structure and reaction.

    3. Studying the relationship between structure and mechanism.

    4. Studying the relationship between structure and activity.


    Correct Option: D
    Explanation:

    Paul Ehrlich promoted chemists "to study the relationship between structure and activity".
    He himself worked on azo dyes, containing $-N=N-$ linkage similar to $-As=As-$ linkage in Salvarsan.

    Which was the first antibacterial discovered by Paul Ehrlich?

    1. Salvarsan

    2. Syphilis

    3. Codeine

    4. None of these


    Correct Option: A
    Explanation:

    The first antibacterial discovered by Paul Ehrlich (a german bacteriologist) was Salvarsan (also called arsphenamine).
    In 1908, he got Nobel prize for discovering arsphenamine (salvarsan) to kill syphilis bacteria.

    In 1932, which medicine was prepared by Paul Ehrlich?

    1. Sulpha drug

    2. Prontosil

    3. azodye

    4. none of these


    Correct Option: B
    Explanation:

    In 1932, Paul Ehrlich prepared antibiotic Prontosil.
    Prontosil contains $-N=N-$ linkage similar to $-As=As-$ linkage in Salvarsan. In human body, the sulpha drug prontosil gets converted into sulphanilamide.

    Which hormone suppresses ovulation in women?

    1. Progesterone

    2. Estrogen

    3. Chloroxylenol

    4. Prontosils


    Correct Option: A
    Explanation:

    Women commonly take progesterone to help start menstrual periods that unexpectedly stopped, treat abnormal uterine bleeding associated with hormonal imbalance, and treat severe symptoms of premenstrual syndrome (PMS). Progesterone is also used in combination with the hormone estrogen to "oppose estrogen" as part of hormone replacement therapy. If estrogen is given without progesterone, estrogen increases the risk of uterine cancer.

    Antimicrobials affect on which type of microorganisms?

    1. Bacteria

    2. Viruses

    3. Fungi

    4. all of these


    Correct Option: D
    Explanation:

    The chemical substances used to cure diseases caused by microbes or microorganism such as bacteria, viruses, fungi, etc., are called antimicrobials.

    Antimicrobial drugs that are derived from the natural processes of some microorganisms and that can inhibit or destroy other microorganisms, are specifically known as:

    1. synthetic drugs

    2. chemotherapeutic drugs

    3. antibiotics

    4. prophylactic drugs


    Correct Option: C
    Explanation:

    Antimicrobial drugs are derived from the natural process of some micro organism that can inhibit or destroy other micro organism are known as antibiotics.

    Example of antibiotics are Paracetamol.

    During sewage treatment, biogases are produced which include :

    1. methane, hydrogensulphide, carbon dioxide

    2. methane, oxygen, hydrogensulphide

    3. hydrogensulphide, methane, sulphur dioxide

    4. hydrogensulphide, nitrogen, methane


    Correct Option: A
    Explanation:

    During sewage treatment in secondary treatment the biogas is produced in anaerotric sludge digestor have anaerobic bacteria which produce gases like $CO _2$, $H _2S$, $CH _4$

    The chemical name of 'Aspirin' is :

    1. benzyl salicylate

    2. acetyl salicyclic acid

    3. acetyl cynamide

    4. tartaric acid


    Correct Option: B
    Explanation:

    The chemical name of 'Aspirin' is-Acetyl salicylic acid or 2-Acetoxybenzoic acid or 2-(Acetyloxy)benzoic acid.

    Chloramines$-T$ is a:

    1. Disinfectant

    2. Antiseptic

    3. Analgesic

    4. Antipyretic


    Correct Option: A
    Explanation:

    Chloramines-T is a N-chlorinated and N-deprotonated sulfonamide used as a biocide and a mild disinfectant. It is a white powder that gives unstable solutions with water.

    Hence, answer is option A.

    Aspirin is administered in the from of a salt or in the presence of $NaHCO _3$. This is to avoid the side effect of a compound $X$ obtained during hydrolysis. Here $X$ is

    1. Sulphuric acid

    2. Acetic acid

    3. Phenol

    4. 2-hydroxy benzoic acid


    Correct Option: A

    The antiseptic action of $CHI _3$ is due to 

    1. Liberation of free iodine

    2. Iodoform

    3. Partially due to iodine and partically due to $CHI _3$ itself

    4. None of these


    Correct Option: B

    Which of the following statements is/are not correct?

    1. Antipyretics are substances which are used to reduce the body temperature.

    2. Analgesics are substance which are used to relieve pain.

    3. Antiseptics and disinfectants can be used for the same purposes.

    4. Antiseptics can be safely applied on living tissues.


    Correct Option: C
    Explanation:

    Antiseptics and disinfectants cannot be used for the same purposes. Antiseptics are applied to living tissues whereas disinfectants are applied to non living tissues. However, both antiseptics and disinfectants kill micro organisms.

    Most contraceptive pills contain:

    1. norethindrone

    2. ethynylestradiol

    3. both A and B

    4. equanil


    Correct Option: C
    Explanation:
    Norethindrone is an example of a synthetic progesterone derivative, most widely used as an anti-fertility drug. The estrogen derivative which is used in combination with progesterone derivative is ethynylestradiol (novestrol). So, both are anti-fertility drugs.

    1% Phenol is used as

    1. Disinfectant

    2. Antiseptic

    3. Antifertility drug

    4. Artificial sweetener


    Correct Option: A
    Explanation:

    One per cent solution of phenol is used as a disinfectant and $0.2$ per cent solution of phenol is an antiseptic so a higher concentration of the same compound is harmful to the body but can be used as a disinfectant to kill microorganisms on the non-living thing.

    Which of the following is an insecticide?

    1. Bakelite

    2. Aspirin

    3. DDT

    4. TNT


    Correct Option: C
    Explanation:

    DDT (dichlorodiphenyltrichloroethane) is an organochlorine insecticide which is a colorless, crystalline solid, tasteless and almost odourless chemical compound.

    Trinitrotoluene (2,4,6-trintrotoluene, TNT) is an extensively used explosive, which has been detected in soil and water at military sites and at munitions manufacturing and training operations.

    Option C is correct.

    Smallpox vaccine contains:

    1. chemical medicines

    2. enzymes

    3. killed or dead microorganisms

    4. living microorganisms


    Correct Option: C
    Explanation:
    Smallpox vaccine contains killed or dead microorganisms. The smallpox vaccine helps the body develop immunity to smallpox disease. The vaccine is made from a virus called 'vaccinia' which is a pox-type virus related to smallpox.

    The $pK _{a}$ of acetylsalicylic acid (aspirin) is $3.5$. The $pH$ of gastric juice in human stomach is about $2$ to $3$ and the $pH$ in the small intestine is about $8$. Aspirin will be

    1. unionized in the small intestine as well as in the stomach.

    2. completely ionized in the small intestine as well as in the stomach.

    3. ionized in the stomach and almost unionized in the small intestine.

    4. ionized in the small intestine and almost unionized in the stomach.


    Correct Option: D

    Salvarsan is an arsenic containing drug, which was first used for the treatment of:

    1. Syphilis

    2. Typhoid

    3. Meningitis

    4. Dysentery


    Correct Option: A
    Explanation:

    Salvarsan was first used in the treatment of Syphilis. It was also used to treat trypanosomiasis. 

    Chloroquin is a drug which is used to control:

    1. Pneumonia

    2. Malaria

    3. Pain

    4. Ordinary fever


    Correct Option: B
    Explanation:

    Chloroquine is a drug which is used in the treatment and prevention of Malaria. It is an aminoquinoline.

    Which of the following represents a biliquid propellant?

    1. Nitroglycerin + Nitrocellulose

    2. $N _2O _4 +$ acrylic rubber

    3. $N _2O _4 +$ Unsymmetrical dimethylhydrazine

    4. Polybutadiene + Ammonium perchlorate

    5. None of the above


    Correct Option: C
    Explanation:
    Nitroglycerin is combined with nitrocellulose to form gunpowders.

    $N _2O _4$ is added to acrylic rubber to increase its tensile strength.

    Unsymmetrical dimethylhydrazine with $N _2O _4$ is used as a hypergolic liquid rocket propellant.

    Ammonium perchlorate in combination with polybutadiene is used as a solid composite propellant. 

    Hence, option C is correct.

    Compound which is added to soap to impart antiseptic properties is:

    1. sodium lauryl sulphate.

    2. sodium dodecylbenzenesulfonate.

    3. rosin.

    4. bithionol.


    Correct Option: D
    Explanation:

    A) Sodium lauryl sulphate - Used in detergents. Common component of cleansing products.

    B) Sodium dodecylbenzenesulfonate - Major component of detergent.

    C) Rosin - A solid form of resin obtained from pines.

    D) Bithionol - Antiseptic added to soap. Used to treat tapeworms and liver flukes.

    Compound with antiseptic properties are:

    1. $CHCl _3$

    2. $CHI _3$

    3.  $ Boric$  $acid $

    4. $0.3$  $ppm $ $Cl _2$


    Correct Option: B,C
    Explanation:
    Antiseptics are anti microbial substances that are applied to living tissue or skin to reduce the possibility of infection.
    $CHI _3$ and Boric acid $($chemically known as orthoboric acid $(H _3BO _3))$ are used as antiseptics.

    Which of the following are sulpha drugs?

    1. Sulphapyridine

    2. Prontosil

    3. Salvarsan

    4. Nardil


    Correct Option: A,B
    Explanation:
    Sulfonamide is the basis of several groups of drugs. The original antibacterial sulfonamides (sometimes called sulfa drugs or sulpha drugs) are synthetic antimicrobial agents that contain the Sulfonamide group. 
    Sulfapyridine is a sulfonamide antibacterial.
    Prontosil: Also known as Sulphamidochrysoidine, it was the first sulfa drug to be discovered. 
    Salvarsan: Also known as Arsphenamine, it was the first modern chemotherapeutic agent.
    Nardil is a monoamine oxidase inhibitor (MAOI).
    So, sulphapyridine and prontosil are the only sulfa drugs here.

    Chloramine-T is a

    1. disinfectant

    2. antiseptic

    3. analgesic

    4. antipyretics


    Correct Option: A
    Explanation:

    Chloramine –T is a disinfectant and an allergen. It is an organic sodium salt derivative of toluene-4-sulfonamide with a chloro substituent in place of an amino hydrogen.


    Hence, option A is correct.

    Difluorodiphenyl trichloroethane (DDFT) is a/an:

    1. refrigerant

    2. fungicide

    3. plastic

    4. antiseptic


    Correct Option: B
    Explanation:

    Difluorodiphenyl trichloroethane (DDFT), similar to DDT, is used as a fungicide.

    Which one of the following is used as a disinfectant in water treatment?

    1. Alum

    2. Charcoal

    3. Kieselguhr

    4. Potassium permanganate


    Correct Option: D
    Explanation:

    Water disinfection means removal, deactivation or killing of pathogenic microorganisms. Microorganisms are destroyed or deactivated resulting in termination of growth and reproduction.

    Potassium permanganate is a weak disinfectant, hence, used in water. 

    What are used to kill or prevent the growth of bacteria?

    1. Antiseptics

    2. Antipyretic

    3. Antidiuretic

    4. Antibiotic


    Correct Option: A,D
    Explanation:
    Antiseptics and antibiotics are the chemical substances which will prevent the growth of bacteria. Antipyretics are the chemical substances which reduce the body temperature. Antidiuretic is an agent that reduces the output of urine.

    Formalin is the other name for:

    1. formic acid

    2. 40% solution of formaldehyde

    3. chloroform

    4. lodoform


    Correct Option: B

    These antiseptics can also be used as disinfectants, which depends on the concentration of the compound.

    1. True

    2. False


    Correct Option: A
    Explanation:

    Disinfectants are antimicrobial agents that are applied to the surface of non-living objects.

    Antiseptic can also be used as disinfectants which depends on the concentration of the compound. So, the statement is true.

    Which of the following are natural antimicrobial chemicals secreted by the body?

    1. Lactic acid

    2. Urea

    3. Hydrochloric acid

    4. Lysozyme


    Correct Option: A,C,D
    Explanation:

    An antimicrobial is an agent that kills micro-organisms or inhibits their growth.

    HCl is secreted by the stomach. 
    Lactic acid is naturally present in humans, as well as in animals. It is well known that it is formed from glycogen by muscle cells when the oxygen supply is inadequate to support energy production.
    Lysozyme is present in the body, abundant in tears, saliva, mucus and milk.
    Urea is a waste from the human body, not an antimicrobial.

    It is found in such as which cause dysentery?

    1. Other microbes

    2. Bacteria

    3. Nutrients

    4. Inorganic impurities


    Correct Option: A
    Explanation:

    Dysentery can be caused by bacteria, virus, or other parasites which cause inflammation of intestines accompanied by bloody diarrhoea.

    Chloramine-T is a:

    1. disinfectant

    2. antiseptic

    3. analgesic

    4. antipyretic


    Correct Option: B
    Explanation:

    Antiseptics drugs cause destruction of micro organisms, which produce septic diseases, eg. dettol, savlon, acriflavin, boric acid, phenol, iodoform, $KMn{O} _{4}$ and some dyes such as chloramine-T, methylene blue.

    Chloramine-T is used as:

    1. antipyretic

    2. analgestic

    3. antiseptic

    4. disinfectant


    Correct Option: C
    Explanation:

    Chloramine-T is antiseptic. Chemically it is sodium salt of p-toluene sulphonamide.

    The oxidant which is used as an antiseptic is.

    1. $PbBr{ O } _{ 3 }$

    2. $KBr{ O } _{ 3 }$

    3. $Cr{ O } _{ 3 }$

    4. $KN{ O } _{ 3 }$


    Correct Option: B
    Explanation:

    $KMn{O} _{4}$ is a powerful oxidising agent in all mediums and it is used as an antiseptic.

    _________ tends to destroy/prevent development or inhibit the pathogenic action of microbes such as bacteria ,fungi, virus, or other parasites selectively.

    1. Histamine

    2. Antibiotic

    3. Antiseptic

    4. Disinfectant


    Correct Option: B,C,D
    Explanation:

    An antimicrobial tends to destroy/prevent development or inhibit the pathogenic action of microbes such as bacteria (antibacterial drugs), fungi (antifungal agents), virus (antiviral agents), or other parasites (antiparasitic drugs) selectively. Antibiotics, antiseptics and disinfectants are antimicrobial drugs.

    Sulphanilamide is a/an:

    1. sulpha drug

    2. antibiotic drug

    3. disinfectant

    4. antacid


    Correct Option: A,B
    Explanation:

    Antibiotics containing chemicals called sulfonamides are called suplha drugs.
    In the body, prontosilis converted to a compound called sulphanilamide, which is the real active compound as antibacterial agent.

    _______ are applied to inanimate objects such as floors, drainage system, instruments, etc.

    1. Disinfectants

    2. Antiseptics

    3. Antacids

    4. Antibiotics


    Correct Option: A
    Explanation:

    Antiseptics and disinfectants are the chemicals which either kill or prevent the growth of microorganisms. Disinfectants are for non-living things while antiseptics are for living tissues.

    Soframicine is a/an:

    1. antiseptic

    2. disinfectant

    3. antifertility drug

    4. anti-histamine


    Correct Option: A
    Explanation:

    Antiseptics are applied to the living tissues such as wounds, cuts, ulcers and diseased skin surfaces. Examples are furacine, soframicine, etc.

    Chlorine in the concentration of 0.2 to 0.4 ppm in aqueous solution, mixed with sulphur dioxide in very low concentrations, form _______.

    1. disinfectants

    2. antibiotics

    3. antiseptics

    4. none of the above


    Correct Option: A
    Explanation:

    Antiseptics acts as disinfectants at low concentration of solution.

    Chlorine in concentration of $0.2$ to $0.4$ $ppm$ in aqueous solution, mixed with $SO _2$ at low concentration is a disinfectant.

    Who was Paul Ehrlich?

    1. Bacteriologist

    2. Chemist

    3. Botanist

    4. None of these


    Correct Option: A
    Explanation:

    Paul Ehrlich was a German Bacteriologist. He prepared compounds containing arsenic for treating syphilis. In 1908, he got the Nobel Prize for discovering arsphenamine (salvarsan) to kill syphilis bacteria. He also worked on azo dyes containing $-N=N-$ linkage similar to $-As=As-$ linkage in salvarsan, and prepared antibiotic protonsil.

    Which type of organisms are called as pathogens?

    1. The organisms which cause a disease .

    2. The organisms which cause weakness .

    3. The organisms which cause an infection .

    4. none of these


    Correct Option: A
    Explanation:

    Pathogens are the type of organisms which cause diseases, by attacking on the defense mechanism of body.

    Protonsil is converted to a compound called:

    1. sulphapyridine

    2. arsphenamine

    3. salvarsan

    4. sulphanilamide


    Correct Option: D
    Explanation:

    Protonsil also called as sulfamido chrysoine is first synthetic drug used in treatment of general bacterial infections in humans. Protonsil converts into sulfoamide in the body which prevent bacterial infection.

    The greatest number of antimicrobic allergies is reported for which drug?

    1. Sulfonamides

    2. Quinolones

    3. Tetracycline

    4. Penicillin


    Correct Option: D
    Explanation:

    Penicillin, one of the first and still one of the most widely used antibiotic agents, derived from the Penicillium mold.In 1928 Scottish bacteriologist Alexander Fleming first observed that colonies of the bacterium staphylococcus aureus failed to grow in those area of a culture that had been accidentally contaminated by the green mold Penicillium notatum.The greatest number of antimicrobic allergies is also reported for Penicillins 

    Which antibacterial drug does not inhibit protein synthesis?

    1. Tetracycline

    2. Penicillin

    3. Chloramphenicol

    4. Erythromycin


    Correct Option: C
    Explanation:

    Chloramphenicol interact acts with SOS subunit, of ribosome and prevents the formation of peptide bonds when chloramphenicol is around, amino acid beads can't be linked together into polypeptide strings.

    Drugs, that affect the bacterial cell wall, are active only against what type of cells?

    1. Gram negative

    2. Young, actively growing

    3. Dormant

    4. Gram variable


    Correct Option: B
    Explanation:

    Drugs affect the bacterial cell wall which is made of phospholipids. These drugs are active against young and actively growing bacteria.


    Hence, the correct option is $B$

    Which of the following statements is accurate in explaining why Gram negative bacteria are generally more resistant to penicillins than Gram positive bacteria?

    1. Gram negative bacteria have a thicker cell wall

    2. Gram negative bacteria have an outer hydrophilic membrane that acts as an extra barrier

    3. Gram negative bacteria can concentrate $\beta$-lactamase enzymes in the periplasmic space

    4. Gram negative bacteria produce smaller quantities of transpeptidase enzyme


    Correct Option: C
    Explanation:

    Gram negative bacteria can concentrate $\beta$-lactamase enzymes in the perplasmic space between the cell wall and the outer membrane. Some Gram positive bacteria can produce $\beta$-lactamase enzyme, but these enzymes diffuse away from the cell because there is no outer membrane to trap them . Thus, they are less effective than $\beta$-lactamases produced by Gram negative bacteria.

    The golden age of antibiotics began in 1928 with Sir Alexander Fleming's discovery of an antibacterial compound he called:

    1. salvarsan

    2. arsenic

    3. sulfonamide

    4. penicillin


    Correct Option: D
    Explanation:

    Penicillin was discovered in 1928 by Scottish scientist Alexander Fleming. People began using it to treat infections in 1942. There are several enhanced penicillin families which are effective against additional bacteria; these include the antistaphylococcal penicillins, aminopenicillins, and the antipseudomonal penicillins. They are derived from Penicillium fungi.

    Birth control pills as antifertility drugs, essentially contain a mixture of synthetic estrogen and _____________  hormones.

    1. protonsil

    2. progesterone derivative

    3. chloroxylenol

    4. quaternary ammonium salt


    Correct Option: B
    Explanation:

    Estrogen and progesterone are the female hormones that are associated with ovulation and menstruation in females. Besides this, both play important role in pregnancy.

    The birth control pills are the derivative of these estrogens and progesterone.

    The birth control pills are which kind of drug?

    1. analgesics

    2. tranquilizers

    3. sulphapyridine

    4. antifertility


    Correct Option: D
    Explanation:

    Antifertility agents are drugs that control fertility and are also called oral contraceptives. These drugs affect and are involved in the menstrual cycle and ovulation in females. Estrogen and progesterone in combined form are given as birth control pills. The antifertility substance is deemed to be active in females when it prevents fertilization, prevent ovulation, implantation, and destroys the zygote or causes abortion.

    The estrogen derivative which is used in combination with progesterone derivative is __________.

    1. Novestrol

    2. Dysidazirine

    3. Chloramphenicol

    4. Amoxycillin


    Correct Option: A
    Explanation:

    Ethinylestradiol (Novestrol) is an estrogen medication which is used widely in birth control pills in combination with progestins. It is also occasionally used as a component of menopausal hormone therapy for the treatment of menopausal symptoms in combination with progestins.

    Most widely used antifertility drug is:

    1. vancomycin

    2. ranitidine

    3. norethindrone

    4. none of these


    Correct Option: C
    Explanation:

    Norethindrone is a synthetic progesterone most commonly used antifertility drugs. A chemical substance which is used to check pregnancy in women is called antifertility drug.

    Which of the following are the antispasmodics?

    1. Dicycloverine

    2. Atropine

    3. Propantheline

    4. All the above


    Correct Option: D
    Explanation:

    There are two main types, as follows.

    Antimuscarinics such as:

    Dicycloverine

    Hyoscine

    Atropine

    Propanthaline

    Smooth muscle relaxants such as:

    • Alverine
    • Mebeverine
    • Peppermint oil
    • Hence option D is correct.

    Alverine and Mebeverine drugs belong to which class of antispasmodics?

    1. Antimuscarinics

    2. Smooth muscle relaxants

    3. A,B

    4. None of the above


    Correct Option: B
    Explanation:

    There are two main types of anti plasmodics, as follows. Antimuscarinics such as Dicycloverine, Hyoscine, Atropine and Propantheline

    Smooth muscle relaxants such as Alverine, Mebeverine and Peppermint oil Hence option B is correct

    Lysine is used as:

    1. disinfectant

    2. germ killer

    3. treating eye disease

    4. anti-cancer drug


    Correct Option: B,C,D
    Explanation:

    Lysine is used for treating eye disease and as an anti-cancer drug because it is a nutritional supplement containing the biologically active L-isomer of the essential amino acid lysine, with potential anti-mucositis activity.
    People use it to make medicine, also used for preventing and treating cold sores. 

    Refer to the given paragraph and answer the following question. Plant P is the only source of food for the caterpillars of a butterfly species, Q. Plant P depends on the adults of the butterfly species Q for pollination. Infact, animal Q is the only pollinator of plant P in nature. Animal R feeds exclusively on the caterpillars of the butterfly species, Q. Animal R In turn is the prey of animal S. Which of the following is likely to happen if animal S is hunted to extinction?

    1. Animal R wit continuously feed on animal Q which may lead to coex-tinction of both P and Q with time.

    2. The populations of both animals Q and R will increase, however the population of plant P will decrease with time.

    3. Population of animal R will Increase while population of animal Q will decrease with time.

    4. Both (A) and (C)


    Correct Option: D
    Explanation:

    According to the given paragraph. P and Q show mutual relationship, i.e. if Q will extinct then it will lead to extinction of Pas well and vice versa. If animal S is hunted to extinction, then population of animal R will start increasing abnormally in the absence of its predator. This uncontrolled growing population of R will feed more on Q population which may ultimately lead to Its extinction with time. As both P and Q depend on each other for existence hence, P population will start decreasing and ultimately get extinct with time.

     Formalin is a powerful :

    1. preservative and disinfectant

    2. bleaching and whitening agent

    3. painkiller

    4. deodorant


    Correct Option: A
    Explanation:

    It is used in tanning, preserving, and embalming and as a germicide, fungicide, and insecticide for plants and vegetables, but its largest applications is in the production of certain polymeric materials.

    Aspirin, a drug for curing headaches and pain is:

    1. pyridine

    2. acetylsalicylic acid

    3. anthraquinone

    4. benzaldehyde


    Correct Option: B
    Explanation:

    (B) acetylsalicylic acid

    Aspirin, also known as acetylsalicylic acid is a non-steroidal, non-inflammatory drug. Due to its analgesic, anti-inflammatory, and antipyretic properties, it is used to treat pain, fever or inflammation. It is produced by acetylation of salicylic acid.

    __________ is a disinfectant and is used for the preservation of zoological samples.

    1. Formaldehyde

    2. Acetic acid

    3. Ketone

    4. Alcohol


    Correct Option: A
    Explanation:

    Formaldehyde in its aqueous solution called formalin (40% formaldehyde) is used as a disinfectant and for preserving the samples in labs.

    Which of the following solution is used as washing solution for eyes to free them from microorganisms?

    1. $1\%$ Phenol solution

    2. $2-3\%$ Iodine solution

    3. $0.2\%$ Phenol solution

    4. Dilute aqueous solution of Boric acid


    Correct Option: D
    Explanation:

    Boric acid is the active ingredient contained in some brands of multipurpose contact lens cleaning solutions. Like hydrogen peroxide, boric acid is a disinfectant and anti-fungal agent used in contact lens solutions to prevent the growth of microorganisms on the eye. 

    option D is correct

    Antiseptics are a class of chemotherapeutic drugs.

    1. True

    2. False

    3. Either

    4. Neither


    Correct Option: B
    Explanation:

    Chemotherapeutic agents are drugs, primarily antibiotics, that are taken internally to fight/kill microbes, whereas antiseptics are chemicals that are applied to skin and tissue directly to fight/kill microbes.

    Which of the following is incorrect for benefits of antifertility drugs?

    1. They cause no interference in sexual activities and risk of pregnancy is reduced.

    2. The chance of cancer in uterus is increased if the pills are taken in long term dose.

    3. They can be taken immediately after childbirth.

    4. They might cause reduction in menstrual bleeding.


    Correct Option: B
    Explanation:

    These drugs generally do not have many side effects, weight gain is the only issue know to be reported. These drugs are very useful if taken in the in the proper dose, following are its significant benefits:

    1. They cause no interference in sexual activities and the risk of pregnancy is reduced.
    2. They might cause a reduction in menstrual bleeding.
    3. They can be taken immediately after childbirth.

    - Hide questions