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Chromosome and its structure - class-XI

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During cell division, spindle fibers attach to which part of chromosomes?

  1. Primary constriction

  2. Secondary constriction

  3. Chromomere

  4. Chromatid


Correct Option: A
Explanation:

During cell division, spindle fibers attach to primary constriction of the chromosomes. Spindle fibres are mainly composed of microtubules which contract and relax to align the chromosomes at a particular orientation.

So, the correct answer is option A.

Bead like thickened portions of leptotene chromosomes are 

  1. Centromeres

  2. Chromomeres

  3. Centrioles

  4. Chromocenters


Correct Option: B
Explanation:

Bead-like thickened portions of leptotene chromosomes is chromomeres. During the leptotene stage, those duplicated chromosomes each consisting of two sister chromatids condense from diffuse chromatin into long, thin strands that are more visible within the cytoplasm.

So, the correct answer is option B.

Most of the DNA of living beings is present in the 

  1. Cytosome

  2. Nucleosome

  3. Chromosme

  4. Protosome


Correct Option: C
Explanation:

A chromosome is composed of DNA and proteins. DNA are the hereditary units which mainly carries the information from one generation to the other. The functional segments of the DNA are known as genes. Proteins are mainly present as histones which form a complex structure known as a nucleosome.

So, the correct answer is option C.

Apart from sex chromosome, which is the other type of chromosome?

  1. Autosome

  2. Cytosome

  3. Both A and B

  4. Protosome


Correct Option: A
Explanation:

Chromosomes in humans can be divided into two types, autosomes, and sex chromosome. The sex chromosomes carry the characters linked to a particular trait. The autosomes contain the rest of the genetic hereditary information. Human cells have 23 pairs of chromosomes (22 pairs of autosomes and one pair of sex chromosomes), giving a total of 46 per cell.

So, the correct answer is option A. 

.......... gives chromosome its characteristic shape.

  1. Centrosome

  2. Centromere

  3. Centriole

  4. P-arm


Correct Option: B
Explanation:
A chromosome is composed of DNA and proteins. DNA are the hereditary units which mainly carries the information from one generation to the other. The functional segments of the DNA are known as genes. Proteins are mainly present as histones which form a complex structure known as a nucleosome.
Each chromosome has a point where sister chromatids attached and give shape to the chromosome, called as the centromere, which divides the chromosome into two sections, or arms. It can be used to describe the location of specific genes. 
So, the correct answer is option B.

By which chromosomes are made of?

  1. DNA and RNA

  2. DNA and proteins

  3. DNA only

  4. Proteins only


Correct Option: B
Explanation:
  • Chromosomes are thread-like structures located inside the nucleus of animal and plant cells.
  •  Each chromosome is made of protein and a single molecule of deoxyribonucleic acid (DNA). Passed from parents to offspring, DNA contains the specific instructions that make each type of living creature unique.

Chromosomes contain information for inheritance of features from parents to next generation in the form of 

  1. DNA

  2. RNA

  3. Proteins

  4. Chromatin


Correct Option: A
Explanation:

Chromosomes are composed of DNA and proteins. DNA molecules contain the information necessary for constructing and organizing the cells. Functional segments of DNA are called as genes. In a cell, which is not dividing, this DNA is present as part of a chromatin material. Whenever the cell is about to divide, the chromatin material gets organized into chromosomes and transferred  to the next generation.

So, the correct answer is option A.

Chromosome carry .......... which helps in the inheritance or transfer of characters from the parents to the offspring.

  1. Genes

  2. Enzymes

  3. RNA

  4. None of the above


Correct Option: A
Explanation:

The nucleus of a cell contains chromosomes, which carry genetic information in a long molecule called as DNA. Genes are regions of DNA that carry the code to control a particular cell activity or the production of a particular protein.

So, the correct answer is option A.

The sex chromosomes of plants were first discovered in

  1. Algae

  2. Fungi

  3. Pteridophyta

  4. Flowering plants


Correct Option: D
Explanation:

Sex determination method is well understood in animals but not in plants. Plants may be monoecious or dioecious but the mechanism of sex differentiation was not well understood. It now appears that at least higher or flowering plants may be having sex determination mechanism based on sex chromosomes like animals, as humans which have XX and XY system of sex determination.

So, the correct answer is option D.

Eukaryotic chromosomes always exist

  1. In pairs

  2. In association with mitochondria

  3. Singly

  4. None of the above


Correct Option: D
Explanation:

Let's take Human somatic cell as an example for the typical eukaryotic cell.

The Human somatic cell is diploid that means the chromosomes exists in double number. 
And these chromosomes in the eukaryotic cell are located in the nucleus and no where associated with mitochondria.
The human somatic cell has 23 pairs of chromosomes but there are 24 types of chromosomes because X and Y chromosomes which are called as sex chromosomes were structurally not similar. 
The remaining 22 types of chromosomes exists in pairs which are homologous (structurally relative) with their pairs.
Hence, all the chromosomes doesn't exist in pairs.
And during the cell division process the homologous chromosomes were separated to opposite poles and therefore doesn't always exists in pairs.
And they also don't exist always in single.

The structure present over chromosome

  1. Nucleolus

  2. Centromere

  3. Centrochrome

  4. Golgi bodies


Correct Option: B
Explanation:

Centromere is a region of chromosomes which holds sister chromatids together and the area where chromosome are attached to spindle fibres during cell division.

In man the normal number of

chromosomes is

  1. 42

  2. 44

  3. 46

  4. 48


Correct Option: C
Explanation:

At first time Tizo and Levan in 1956 enabled the human geneticists to as certain the correct chromosome number (46 pairs).

Chromatid is

  1. One half of chromosome

  2. Haploid chromosome

  3. Complete chromosome

  4. Duplicate chromosome


Correct Option: A
Explanation:
1) A chromatid is one-half of two identical copies of a replicated chromosome. During cell division, the identical copies are joined together at centromere. Joined chromatids are known as sister chromatids. Once the joined sister chromatids separate from one another in anaphase of mitosis, each is known as a daughter chromosome.

2) In gamete cells, the cell contains half the number of chromosomes as body cells, are called Haploid chromosomes.

3) Body cells such as muscle,skinblood etc. These cells contains a complete set of chromosomes (46 in humans),are called Diploid or complete chromosomes.

So, the correct answer is 'One half of chromosome'.

The nuclear component that contains genes which are responsible for heredity or transfer of characteristics from parents to children is/are

  1. the Chromosomes

  2. the Cytoplasm

  3. the Nucleolus

  4. All of the above


Correct Option: A
Explanation:

The chromosomes are thread-like structures which can be seen enclosed in a cell nucleus. These chromosomes contain genes which are responsible for the transfer of characteristics from parents to the children.

Choose the correct statement.

  1. Genes are located in the chromosomes

  2. Cell is locked in the nucleus

  3. Chromosomes are located in the nucleolus

  4. Cell membrane surrounds the nucleus


Correct Option: A
Explanation:

The chromosomes are the condensed chromatin. They are made up of DNA and proteins Those sequences of DNA that code for proteins are called the genes. 

A. Genes are the segment of DNA that is located in the chromosome. The location of a gene on a chromosome is called the locus.
B. Nucleus is an organelle present inside the cell.
C. Nucleolus is the region on chromosomes that forms the ribosomal RNA.
D. Nuclear membrane surrounds the nucleus. Cell membrane surrounds the cell.
Hence, the correct answer is 'Genes are located in the chromosomes'

Chemical composition of chromosome : 

  1. DNA and lipids

  2. DNA and carbohydrates

  3. Proteins and lipids

  4. DNA and proteins


Correct Option: D
Explanation:

The chemical composition of a chromosome is DNA and proteins(histone). Because chromosome is a supercoiled structure made up by coiling of DNA on the proteins like histone

So the correct option is"DNA and Proteins".

How many sets are represented in the species with 156 chromosomes ?

  1. 12

  2. 78

  3. 39

  4. 19


Correct Option: B
Explanation:

The single set of chromosome consists of half the total number of chromosomes, also called a haploid set. Here, a total of 156 chromosomes is there so one set will have 78 chromosomes.


So, the correct answer is ' B '

Chromosome have an ability of?

  1. Autophagosis

  2. Self-replication

  3. Self-destruction

  4. None of these


Correct Option: A

Study of _________ helps in the determination of phylogeny and taxonomy.

  1. Chromosomes

  2. Cytoplasm

  3. Nucleoplasm

  4. Sarcoplasm


Correct Option: A

Who proposed that chromosomes carried a different set of heritable elements?

  1. Walther Flemming

  2. Wilhelm Roux

  3. Robert Remark

  4. Virchow


Correct Option: A

Who hypothesised that individuals of the same species have the same number of chromosomes?

  1. Augustus Weisemann

  2. Theodor Boveri

  3. Wilhelm Roux

  4. Robert Remark


Correct Option: A

Sometimes a few chromosomes have non staining secondary constriction at a constant location. This gives the appearance of a small fragment, called : 

  1. NOR

  2. Satellite

  3. Telomere

  4. kinetochore


Correct Option: A

Which of the following statements is incorrect?

  1. Every chromosomes essentially has a secondary constriction

  2. The interphase nucleus has a loose and indistinct network of nucleoprotein fibres called chromatin

  3. A single human cell has approximately $2.2$ metre long thread of DNA distributed among its forty six chromosomes

  4. Chromatin contains DNA and some basic proteins called histone, some non histone proteins and also RNA


Correct Option: A

What would be the number of chromosomes of the aleurone cells of a plant with $42$ chromosomes in its root tip cells?

  1. $21$

  2. $42$

  3. $63$

  4. $84$


Correct Option: A

Chromosome consists of

  1. DNA only

  2. DNA and histone protein

  3. DNA, histone proteins and non-histones proteins

  4. DNA and non-histones protein


Correct Option: C
Explanation:

Chromosomes are made up of DNA and protein. Histone and non-histones proteins are associated with chromosomal DNA. Histone participate as structural components and provide strength and stability and protect DNA from shearing and breakage while the non-histones act as functional or regulatory components either in activation or repression of genes.

So, the correct answer is option C.

The first person to observe chromosome was

  1. Waldayer

  2. Hofmeister

  3. F. Meischer

  4. G. Cuvier


Correct Option: B
Explanation:

Chromosomes were discovered by Hofmeister (1848), studied by Strasburger (1875) and given the present name by Waldeyer (1888) after their staining by dyes like Janus Green. Chromosomes are a thread like structure. It is composed of DNA and protein and it is considered as a carrier of genetic characters from parents to offspring.

So, the correct answer is option B.

Chromosomes are composed of

  1. DNA, RNA, histones, non-histones

  2. DNA and histones

  3. DNA and RNA

  4. DNA, RNA and histones


Correct Option: A
Explanation:

Chromosomes are composed of DNA, RNA, histones, non-histones. A chromosome is a packaged and organized chromatin, a complex of macromolecules found in cells, consisting of DNA and protein. The functional segments of DNA are known as genes. The DNA-bound macromolecules are proteins, which serve to package the DNA and control its functions.

So, the correct answer is option A.

The non-sticky chromosomal ends are known as

  1. Chromatids

  2. Centromere

  3. Chromomere

  4. Telomere


Correct Option: D
Explanation:

The telomeres do not have any overhanging ends of nucleotides so it is known as non sticky chromosome ends called telomere. A telomere is a region of repetitive nucleotide sequences at each end of a chromatid, which protects the end of the chromosome from deterioration or from fusion with neighboring chromosomes. 

So, the correct answer is option D.

Chromonemata are embedded in a

  1. Stroma

  2. Matrix

  3. Sugar

  4. Mucilage


Correct Option: B
Explanation:

Chromonemata are embedded in the matrix. Chromonemata are the spirally coiled central filament of a chromatid along which the chromomeres are aligned. A chromomere is one of the serially aligned beads or granules of a eukaryotic chromosome, resulting from local coiling of a continuous DNA thread. It is visible on a chromosome during the prophase of meiosis and mitosis. 

So, the correct answer is option B.

Bead like structure found on chromosome are called as

  1. Chromomeres

  2. Chromonemata

  3. Chromonema

  4. Centriole


Correct Option: A
Explanation:

A chromomere  is one of the serially aligned beads or granules of a eukaryotic chromosome, resulting from local coiling of a continuous DNA thread. It is visible on a chromosome during the prophase of meiosis and mitosis. The chromomeres are present during leptotene phase of prophase I during meiosis. During zygotene phase of prophase I, the chromomeres of homologs align with each other to form a homologous rough pairing. These chromomeres help provide a unique identity for each homologous pairs.

So, the correct answer is option A.

Exceptionally, large chromosome is

  1. Lampbrush chromosome

  2. Polytene chromosome

  3. Megachromosomes

  4. All of the above


Correct Option: D
Explanation:

All chromosomes mentioned are large chromosomes. These chromosomes are producing large amounts of RNA for the oocyte, and most of the genes present in the DNA loops are being actively expressed. Each lateral loop contains one or several transcription units with polarized RNP-matrix coating the DNA axis of the loop.The majority of the DNA, however, is not in loops but remains highly condensed in the chromomeres on the axis, where genes are generally not expressed. This is about lampbrush chromosomes, the polytene and mega chromosomes are also larger than the other normal chromosomes.

So, the correct answer is option D.

A thread like structure in the nucleus of a cell formed of DNA which carries the genes is

  1. DNA

  2. Genes

  3. Chromosomes

  4. Ribosomes


Correct Option: C
Explanation:

Deoxyribonucleic acid (DNA) is the information-carrying molecule found in all living organisms. In most animal, plant and fungal cells, DNA is stored in the nucleus coiled up in thread-like structures called chromosomes.

So, the correct answer is option C.

Nucleus contains ________ which are rod shaped structures.

  1. Cytoplasm

  2. Chromosomes

  3. Chromatin

  4. Carbon particles


Correct Option: B
Explanation:

Chromosomes are thread like structures located inside the nucleus of animal and plant cells. Each chromosome is made of deoxyribonucleic acid (DNA). Passed from parents to offspring, DNA contains the specific instructions that make each type of living creature unique.

Which chromosomes are called as supernumerary?

  1. B-chromosome

  2. Sex chromosome

  3. Double minutes chormosome

  4. Lampbrush chromosome


Correct Option: A
Explanation:

B chromosomes are called supernumerary or accessory chromosomes. It is because these chromosomes are not considered as essential for being normal. These are not found in every individual. During alloploids, it suppresses homologous pairing which reduces multiple pairing between homologous chromosomes in allopolyploids.  

So, the correct option is A.

Who used the word "chromosome"

  1. Huxley

  2. Flemming 1888

  3. Kollikar 1888

  4. Waldeyer 1888


Correct Option: D
Explanation:
Johannsen coined the term phenotype and genotype and conducted his pure line experiment in genetics.
Waldeyer 1888 used the term chromosome to describe certain structures that form during the process of cell division.
Benda coined the term mitochondria to describe their tendency to form long chains.
Flemming coined the term chromatin and mitosis, and also described the threadlike structure in the cell nucleus that was later named chromosome.
So, the correct option is 'Waldeyer 1888'.

Swellings present over the chromosomes are

  1. Centromeres

  2. Centrosome

  3. Puffs

  4. Chromomeres


Correct Option: A
Explanation:
The centromere is the specialized DNA sequence of a chromosome that links a pair of sister chromatids
During mitosis, spindle fibers attach to the centromere via the kinetochore.
Centromeres were first thought to be genetic loci that directs the behavior of chromosomes
So, the correct answer is 'Centromeres'

Kinetochore is 

  1. Granule within centromere

  2. Surface of centromere

  3. Constriction near chromosome end

  4. End of chromosome


Correct Option: A
Explanation:
The centromere is the lighter staining region on the chromosome of a cell which appears as a constriction.
They are also known as a primary constriction or kinetochore.
The kinetochore is a proteinaceous structure that assembles at the surface of the centromere which forms the site for binding of spindle fibres during cell division.
So, the correct answer is 'Surface of centromere'.

Telomeres

  1. Initiate RNA synthesis

  2. Help chromatids to move towards poles

  3. Seal ends of chromosomes

  4. Identify correct members of homologous pairs of chromosomes.


Correct Option: C
Explanation:
  • A telocentric chromosome is a chromosome in which the centromere is located at the terminal end of the chromosome and their shape is similar to the letter i.
  • These chromosomes have a repetitive nucleotide sequence at each end of chromosomes. 
  • It seals and protects each end of the chromosomes from deterioration or fusion with the neighbouring chromosomes during cell division.
  • So, the correct answer is 'Seal ends of chromosomes'.

A constriction on the chromosome is

  1. Centromere

  2. Centrosome

  3. Centriole

  4. Chromomere.


Correct Option: A
Explanation:
  • The centromere is the lighter staining region on the chromosome of a cell which appears as a constriction.
  • They are also known as a primary constriction or kinetochore.
  • It is a specialized DNA sequence that links a pair of sister chromatids where the spindle fibres are attached during cell division.
  • It is responsible for the transfer of replicated chromosomes into the two daughter cells during the cell division.
  • So, the correct answer is 'Centromere'

Satellite means

  1. Terminal part of the chromosome beyond secondary constriction

  2. Terminal part of the chromosome beyond primary constriction

  3. Terminal part of chromosome beyond tertiary constriction

  4. None of the above


Correct Option: A
Explanation:
  • Satellite chromosomes or SAT chromosomes are those chromosomes which have secondary constrictions other than a centromere.
  • The terminal end of the chromosome present beyond the secondary constriction is called satellite which is attached to the chromosome by a thin thread called chromatin.
  • So, the correct answer is 'Terminal part of the chromosome beyond the secondary constriction'.

Which one is present on chromosome?

  1. Centromere

  2. Centrosome

  3. Nucleus

  4. Golgi body


Correct Option: A
Explanation:
  • The centromere is the lighter staining region present on the chromosome of a cell which appears as a constriction.
  • They are also known as a primary constriction or kinetochore.
  • It is a specialized DNA sequence that links a pair of sister chromatids where the spindle fibres are attached during cell division.
  • So, the correct answer is 'Centromere'.

Sister chromatids are joined at

  1. Chromocentre

  2. Metacentre

  3. Centromere

  4. Telomere


Correct Option: C
Explanation:
  • The specialized DNA sequence that links a pair of sister chromatids where the spindle fibres are attached during cell division is known as a centromere.
  • It is the lighter staining region on the chromosome of a cell which appears as a constriction.
  • They are also known as a primary constriction or kinetochore.
  • So, the correct answer is 'Centromere'.

A duplicated chromosome has how many chromatids

  1. One

  2. Two

  3. Three

  4. Four


Correct Option: B

Kinetochore is

  1. Granule within centromere

  2. Surface of centromere

  3. Constriction near chromosome end

  4. End of chromosome


Correct Option: B
Explanation:
  • The centromere is the lighter staining region on the chromosome of a cell which appears as a constriction.
  • They are also known as a primary constriction or kinetochore.
  • The kinetochore is a proteinaceous structure that assembles at the surface of the centromere which forms the site for binding of spindle fibres during cell division.
  • So, the correct answer is 'Surface of centromere'.

Which statement is not correct

  1. Histones rich in arginine are $H _3$ and $H _4$

  2. Nucleolar organiser is found in the secondary constriction of a chromosome

  3. Polytene chromosomes are found in Chironomus

  4. B-chromosomes are genetically active.


Correct Option: B

The term chromosome was coined by

  1. Hofmeister

  2. Strasburger

  3. Waldeyer

  4. Laemli


Correct Option: C
Explanation:
  • Chromosomes can be defined as thread-like structure which contains DNA and proteins which are found in the nucleus of most living cells.
  • They carry the genetic information in the form of genes.
  • The word chromosome is derived from the Greek word chroma meaning "colour" and soma meaning "body".
  • The term was coined by von Waldeyer-Hartz in relation to the term chromatin which was introduced by Walther Flemming.
  • So, the correct answer is 'Waldeyer'.

Term chromosome was coined by

  1. Hofmeister

  2. Sutton

  3. Boveri

  4. Waldeyer


Correct Option: D
Explanation:

The term "chromosome" (comes from the Greek word "chroma" meaning colour and "soma" meaning "body", describing their strong staining by particular dyes) was first suggested in 1888 by the German anatomist Heinrich Wilhelm Gottfried von Waldeyer-Hartz.


So, the correct answer is 'Waldeyer'

Chromosome theory of inheritance was proposed by

  1. Sutton $(1902)$

  2. Boveri $(1902)$

  3. Both Sutton $(1902)$ and Boveri $(1902)$

  4. Correns $(1909)$


Correct Option: C
Explanation:

Chromosome theory of inheritance or Boveri–Sutton chromosome theory is a fundamental unifying theory of genetics which identifies chromosomes as the carriers of genetic material

So, the correct answer is 'Both Sutton (1902) and Boveri (1902)'.

More than $200$ chromosomes occur in

  1. Chicken

  2. Dog

  3. Amoeba

  4. Gorilla


Correct Option: C
Explanation:

1) Chicken has a diploid number of 78 (2n = 78).

2) Dog has a diploid number of 78 (2n=78).
3) The genome for Amoeba proteus is very large containing over 290 billion base pairs in its genome. The Amoeba proteus has more than 500 chromosomes in a single nucleus.
4) Gorilla has a diploid number of 48 (2n=48).
So, the correct answer is 'Amoeba'.

Chromosomes were first seen by

  1. Hofmeister

  2. Waldeyer

  3. Strasburger

  4. Flemming


Correct Option: A
Explanation:

Wilhelm Friedrich Benedikt Hofmeister observed chromosomes in a dividing cell nucleus in 1848.


So, the correct answer is 'Hofmeister'

In a chromosome the protein content is?

  1. Nil

  2. Trace

  3. Half of DNA

  4. Same as DNA


Correct Option: D

Kinetochore is?

  1. Surface of centromere

  2. Trilaminar plate over centromere

  3. End of chromosome

  4. Constriction near chromosome end


Correct Option: A
Explanation:
The centromere is the lighter staining region on the chromosome of a cell which appears as a constriction.
They are also known as a primary constriction or kinetochore.
The kinetochore is a proteinaceous structure that assembles at the surface of the centromere which forms the site for binding of spindle fibres during cell division.
So, the correct answer is 'Surface of centromere'.

Is chromosome are the chromosomes with _____________.

  1. Identical sizes

  2. Identical arms

  3. Identical gene content

  4. Identical shapes


Correct Option: A

Somatic chromosome number is 40.What shall be chromosome number in the cells seminiferous tubule ?

  1. 40

  2. 20

  3. 10

  4. 40 and 20


Correct Option: B
Explanation:
Somatic cell is diploid (2n) in nature. It is given that the number of somatic chromosomes is 40. Seminiferous tubules contain haploid (n) spermatozoa. These spermatozoa are haploid in nature.
Hence, the number of chromosomes in the cells of seminiferous tubules will be 20.
Thus, the correct answer is '20.'

Separate identical copies of chromosomes are formed at the _______________.

  1. End of metaphase

  2. End of anaphase

  3. End of prophase

  4. End of zygotene


Correct Option: A

A pericentric inversion in chromosome involves _______________.

  1. One arm of a chromosome

  2. Both the arms of a chromosome

  3. Two different chromosomes

  4. More than two chromosomes


Correct Option: A

Is chromosomes are formed by.

  1. Pairing of identical chromosomes

  2. Longitudinal splitting of Centromere

  3. Transverse division of Centromere

  4. Disjunction of bivalents


Correct Option: A

Lamp brush chromosomes found in certain organisms are directly related to metamorphosis. Which one of the following statements in this regard is incorrect?

  1. These are very large chromosomes

  2. These are actively engaged in RNA and protein synthesis and accumulation

  3. Lamp brush loops recede and these become normal looking chromosomal parts looking chromosomal parts

  4. They are compactly packed and have very high DNA content


Correct Option: A

$6$p $23$ in chromosome nomenclature indicates band number.

  1. $6$ in short arm of chromosome $23$

  2. $3$ in region $2$ of short arm of chromosome $6$

  3. $3$ in region $2$ of long arm of chromosome $6$

  4. $6$ in long arm of chromosome $23$


Correct Option: A

Diagrammatic representations of a chromosome is known as ____________.

  1. Homotype

  2. Idiotype

  3. Merotype

  4. Karyotype


Correct Option: B
Explanation:
An ideogram is a diagrammatic representation of the karyotype that shows all of the pairs of homologous chromosomes in the nucleus. The pairs of chromosomes are lined up in order of size, so that the centromeres are aligned and the short arm is uppermost. An ideogram is a useful point of reference for analyzing mutations.
So the correct option is 'Idiotype'.

Match List I(Chromosome aberrations) with List II(consequences) and select the correct a answer using the codes given the lists.

List-I List-II
a. Intercalary deficiency $1$. chromosome ring formation at metaphase
b. Duplication $2$. Bridge and fragment formation
c. Para centric inversion $3$. Change in gene order
d. Translocation $4$. Two breaks followed by reunion and deletion
  1. A-$4$, B-$3$, C-$2$, D-$1$

  2. A-$4$, B-$3$, C-$1$, D-$2$

  3. A-$3$, B-$4$, C-$1$, D-$2$

  4. A-$3$, B-$4$, C-$2$, D-$1$


Correct Option: A

Is chromosome refers to the ______________________.

  1. Chromosome which has been isolated from the rest of the complement

  2. Chromosome which has reached the equatorial plane earlier than the other chromosomes

  3. Tran located chromosome having identical arms

  4. Lagging chromosome which has not moved to either of the pole


Correct Option: A

How are chromatin, chromatid and chromosomes related to each other?

  1. Chromosomes are made up of chromatin

  2. Chromatin is made up of chromosomes

  3. Chromatin is made up of chromatids

  4. Chromosomes are made up of chromatids and chromatids are made up of chromatin


Correct Option: D
Explanation:

Chromatin fibers are made from coiling of a long polynucleotide strand of a DNA to fit into the cell. Chromatids are made up of chromatin. The two sister chromatids are present in a chromosome.

So, the correct answer is option D. 

Choose the correct answer from the alternatives given:
In which part of the cell is DNA concentrated?

  1. Chromosomes

  2. Cell wall

  3. Ribosomes

  4. Golgi body


Correct Option: A
Explanation:

The chromosomes are the threadlike structures of nucleic acids found in the nucleus of most of the living organisms, carrying the genetic material in the form of genes. Thus DNA is concentrated in the chromosomes.

B. The cell wall is the structural component of the cell that gives shape to the cell.
C. Ribosomes and the Golgi body are the organelles present in the cell. Ribosomes help ion protein synthesis.
D. Golgi apparatus helps to process and bundle macromolecules like proteins and lipids that are synthesized in the cell.
Hence, the correct answer is 'Chromosomes'.

Choose the correct answers from the alternatives given :
The thread like structures that begin to radiate from each centromere by the end of prophase are

  1. aster microtubules

  2. spindle microtubules

  3. kinetochore microtubules

  4. polar microtubules


Correct Option: C
Explanation:

  • Prophase is the third stage of the mitosis where the chromosomes which were lined up at the metaphase plate in the metaphase are to be pulled towards the pole of the dividing cells.
  • The centrioles which are present at the pole of the dividing cells produce spindle fibers which are will help pull the chromosomes towards the pole .
  • These spindle fiber will attach to the kinetochore which is present with the centromere in the middle of the chromosome,
  • The kinetochore also produces microtubles which will attach will the incoming spindle fibers forming a bond so that they can be pulled towards the pole.
  • After reaching the pole the fibers will distangle from the kinetochore and disappear leaving the chromosomes to decondense and formation of the nuclear membrane around them .
  • Therefore the answer option 'kinetochore microtubules' is correct.

















Choose the correct answers from the alternatives given :
The centromere or primary constriction of the chromosome contains rings of protein that are intimately associated with a spindle fibre. These rings are called

  1. asters

  2. secondary constrictions

  3. centrioles

  4. kinetochores


Correct Option: D
Explanation:
  • The kinetochore is the region which is present in the center of the chromosome near the centromere or the primary constriction.
  • The spindle fibers which are formed from the centrioles are required to pulled the chromosome towards the poles of the dividing daughter cells.
  • The spindle fiber of the centrioles are attached to the kinetochore which is a protein ring or made up of protein which forms bonds with tubulin protein of the spindle fiber, so that the chromosomes can be pulled apart towards the poles. 
  • Therefore the answer option 'kinetochores' is correct.

Which is not a major function of the genetic material?

  1. Store information

  2. Catalyse chemical reactions

  3. Replicate itself

  4. Undergo mutation


Correct Option: B
Explanation:

Enzymes are present inside cells for catalyzing chemical reactions. While genetic material is present inside the nucleus as storage of information for all the cellular activities in the form of genes. Genetic material replicates during cell division. It can also undergo mutation during replication. 

So, the correct option is 'Catalyse chemical reactions'.

Select the correct option:

Which of the following stains is not used for staining chromosomes?

  1. Basic Fuchsin

  2. Safranin

  3. Methylene green

  4. Carmine


Correct Option: B
Explanation:

Chromosomes are heavily coiled DNA, a DNA molecule is negatively charged and has to be therefore stained with basic dyes like Basic fuchsin, Methylene green and carmine.while safranin is used to stain cell walls of plants and bacteria (counter stain)

So, the correct answer is 'Safranin'

According to most recent studies, each chromosome consists of
  1. Single double helical DNA which is highly coiled and folded

  2. Variable number of DNA helices, depending upon the length of chromosome

  3. Many small DNA helices, which are joined by peptide linkages

  4. Small DNA helices, wrapped around each other like a rope


Correct Option: A
Explanation:

There is a single, long, double-stranded, linear DNA molecule in a chromosome. The DNA contains biological and genetic information. It is highly coiled and folded, however this packing varies during the cell cycle.

So, the correct answer is 'Single double-helical DNA which is highly coiled and folded'.

Mark the correct option w.r.t. chromosomes.

  1. mRNA + ribosomes

  2. mRNA + protein

  3. DNA + Protein

  4. Polyribosomes


Correct Option: C
Explanation:

The nucleus of each cell, the DNA molecule is packaged into thread-like structures called chromosomes. Each chromosome is made up of DNA tightly coiled many times around proteins called histones that support its structure.

So, the correct option is 'DNA + protein.

which of the following is typically not found in normal somatic cells of human male?

  1. the entire genetic information possesed by the original zygote

  2. an inactivated X chromosome

  3. forty four autosomes

  4. a diploid nucleus

  5. A Y chromosomes


Correct Option: B
Explanation:

An inactivated X-chromosomes : female have XX chromosomes and male have XY chromosomes ,for balance Xlinked gene between male and female,one X chromosome undergo inactivated during the female embryo development this is termed as X chromosomes inactivation

Which of the following dyes is best suited for staining chromosomes ?

  1. Basic Fuchsin

  2. Safranin

  3. Methylene blue

  4. Carmine


Correct Option: D
Explanation:

(a) Basic Fuchsin-  It is a green crystalline dye. It includes staining of tissues sections.

(b) Safranin- It is used to stain gram-negative bacteria, mucin, etc.
(c) Methylene blue- It is used to examine DNA or RNA under the microscope.
(d) Carmine -  It is a type of stain used to stain chromosomes, nuclei etc.
So, the correct option is 'Carmine'.

Which of the following does not occur during condensation of chromosomes?

  1. Unfolding of protein molecules

  2. Coiling of DNA

  3. Dehydration

  4. Hydration


Correct Option: D
Explanation:

Chromosome condensation is the dramatic re-organization of the long thin chromatin strands into the compact short chromosomes that occur in mitosis and meiosis. Here, the unfolding of proteins takes place, the DNA coils, dehydration takes place. However, there is no addition of water molecule or hydration that takes place during condensation.

So, the correct answer is option D.

Structure which provide shape to chromosome is called as

  1. Telomere

  2. Satellite

  3. Centromere

  4. Chromomere


Correct Option: C
Explanation:

Centromere provides structure to the cell. The sister chromatids are linked together at the centromere. During mitosis, spindle fibers attach to the centromere via kinetochore. Their physical role is to act as the site of assembly of the kinetochore, a highly complex multiprotein structure that is responsible for the actual events of chromosome segregation, i.e., binding microtubules and send signals to the cell cycle machinery.

So, the correct answer is option C.

Part of chromosome after secondary constriction is called as

  1. Chromomere

  2. Telomere

  3. Satellite

  4. Nucleolar organiser


Correct Option: C
Explanation:

Chromosomes are the carrier of genetic information in form of DNA. The secondary constrictions are used as a point of identification of chromosomes. These are always constant in their positions and hence, can be used as markers that identify particular chromosomes. A satellite chromosome or SAT chromosome has a chromosome segment that is separated from the main body of the chromosome by such a secondary constriction.

So, the correct answer is option C.

General length of chromosome is

  1. 5$\mu$m - 10$\mu$m

  2. 0.2$\mu$m - 2$\mu$m

  3. 0.1$\mu$m - 30$\mu$m

  4. 0.1$\mu$m - 4$\mu$m


Correct Option: C
Explanation:

Chromosomes are the genetic material present in the nucleus of a cell. It is composed of DNA and protein. The functional segment of DNA is known as a gene. The size of chromosomes varies from as small as 0.1$\mu$m to as big as 15$\mu$m in length.

So, the correct answer is option C.

The chromosome that lacks a centromere is called as

  1. Telocentric

  2. Acentric

  3. Metacentric

  4. Acrocentric


Correct Option: B
Explanation:
In acrocentric chromosome, the centromere is present close to the end of the chromosome. Due to this one arm is very short and another arm is longer. 
In metacentric, the centromere is in the middle of the chromosome and the two arms are of equal length. 
In telocentric, the centromere is present at the end of a chromosome.
In acentric the chromosome that lacks a centromere. So, the correct answer is option C.

The largest normal metaphasic chromosome has a size of

  1. $1\mu m$

  2. $10\mu m$

  3. $20\mu m$

  4. $30\mu m$


Correct Option: D
Explanation:

The largest normal metaphasic chromosome has the size of 30nm with the base of the nucleosome core particle consists of the 146 base pairs of DNA. During metaphasic state, when a chromosome in its most condensed state can range in size between 130,000 base pairs in the endosymbiotic bacteria, then the chromatin can be further condensed by coiling into 30nm in fibres.
So, the correct answer is option D.

During staining, chromosomes get stained with

  1. Eosine

  2. Borax carmine

  3. Acetocarmine

  4. Safranin.


Correct Option: C
Explanation:

  • Stains are used in the microscopic studies of different components and organelles within a cell.
A. Eosine is stain used to stain the cytoplasm of the cell because these acidic dyes bind to basic proteins in the cytoplasm of the cell.
B. Borax carmine consists of borax, carmine and water which produces a permanent red nuclear stain which stains the nucleus and the cytoplasm.
C. Acetocarmine is a saturated solution of carmine in 45% of acetic acid which is used for staining the unfixed chromosomes within the nucleus of a cell that is used to study different stages of the chromosomes in cell division.
D. Safranin is a basic counterstain dye used in histology and cytology.

So, the correct answer is 'Acetocarmine'.

The term chromonema was coined by

  1. Flemming

  2. Strasburger

  3. De Robertis

  4. Vijdovsky


Correct Option: D
Explanation:

Chromonema is spirally coiled central filament that extends the entire length of a chromosome and on which the genes are located. During mitotic prophase, the chromosome material appeared as thin filaments which are known as chromonema. This term is introduced by Vijdovsky in 1912. 

It represents chromatids in the early stages of condensation. Hence option D is correct.

Chromosome end is called

  1. Telomere

  2. Centromere

  3. Satellite

  4. Metamere


Correct Option: A
Explanation:
  • A telomere is the end portion of a chromosome.
  • It is a region of repetitive nucleotide sequences present at each end of a chromosome that helps the chromosome from deterioration or fusion with other chromosomes. 
  • So, the correct answer is 'Telomere'.

Parascaris possesses chromosome

  1. Monocentric

  2. Dicentric

  3. Polycentric

  4. Holocentric


Correct Option: C
Explanation:

Parascaris, first studied by Boveri (1887), has polycentric chromosomes, each of which consists of six segments, each segment having one centrally located centromere. So, the correct answer is option C.

Read the given statements
(i) Centromere is present in the middle of the chromosome and forms two equal arms.
(ii) Chromosome has a terminal centromere
(iii) Centromere lies close to the end of the chromosome forming one extremely short and one very long arm
(iv) Centremere lies slightly away from the middle of the chromosome resulting into one shorter arm and one longer arm.
Select the correct option as per the codes given above-

  1. Meta centric- (i); Submeta centric- (iv); Acro centric- (iii); Telo centric- (ii)

  2. Meta centric- (i); Submeta centric- (ii); Acro centric- (iii); Telo centric- (iv)

  3. Meta centric- (iv); Submeta centric- (iv; Acro centric- (iii); Telo centric- (ii)

  4. Meta centric- (iv); Submeta centric- (ii); Acro centric- (iii); Telo centric- (i)


Correct Option: A
Explanation:

Every chromosome has a primary constriction or the centromere on the sides of which kinetochores are present. Based on the position of centromere, the chromosomes are of 4 types:

  • Metacentric -  Centromere is present in the middle of the chromosome and forms two equal arms.
  • Submetacentric -  Centromere lies slightly away from the middle of the chromosome resulting into one shorter arm and one longer arm.
  • Acrocentric - Centromere lies close to the end of the chromosome forming one extremely short and one very long arm. 
  • Telocentric - Chromosome has a terminal centromere. 
  • So, the correct option is 'Option A' .

When stained with a certain dye, the chromosomes show alternate light and dark bands known as Q-bands under the microscope. Name the dye.

  1. Fluorescent dyes

  2. Haematoxylin

  3. Giemsa stain

  4. Quinacrine mustard


Correct Option: D
Explanation:

Q band is a typical pattern which is obtained by using Quinacrine mustard dye. Nucleus located in the centre of each cell has chromosomes coiled in the form of chromatin network. Chromosomes are gene carriers. They are made up of 2 chromatids, that are joined to each other through a centromere. 

heterochromatic DNA which is firmly packed and coiled is commonly stained by this dye. The pattern is similar to that obtained by light and dark bands obtained by G banding. The regions having rich Adenine Thymine complexes are highlighted with yellow fluorescence as seen in Q banding.
So the correct answer is " Quinacrine mustard ".

Synaptinemal complex was first described by

  1. Moses

  2. Bowmann

  3. Montgomery

  4. Pfitzner


Correct Option: A
Explanation:

The snaptinemal complex was first described by Montrose J. Moses and D. Fawcett in 1956. Moses discovered in primary spermatocyte of crayfish and Fawcett discovered in spermatocytes of pigeon, cat, and man etc. It is protein structure that forms between homologous chromosomes during meiosis and mediates chromosome pairing.
So the correct option is A

Match column I with column II and select the correct option from the given codes

Sr.no  List I   Sr.no  List II
 a.  V-shaped at anaphase  1.  Acrocentric chromosome
 b.  L-shaped at anaphase   2.  Metacentric chromosome
 c.  J-shaped at anaphase  3.  Telocentric chromosome
 d.  I- shaped at anaphase  4.  Sub-metacentric chromosome

.

  1. A-(iv),B-(ii),C-(i),D-(iii)

  2. A-(ii),B-(iv),C-(i),D-(iii)

  3. A-(ii),B-(iv),C-(iii),D-(i)

  4. A-(iv),B-(iii),C-(ii),D-(i)


Correct Option: B
Explanation:

Anaphase is a stage where the chromosomes split from the middle and two chromatin get separate and both the chromatids move toward opposite poles due to a repulsive force which is known as an aphasic moment.

The different shapes of chromosome become evident during chromosome movement that is metacentric, acrocentric et cetera. If the chromosome is V-shaped at anaphase then it would be metacentric because it is from the exact centre of the centromere.
 If it is L shaped at anaphase then it will be submetacentric because one arm would be smaller than the other arm. If it is J shaped then it is acrocentric chromosome because it is on one end of the chromosome and if it is I shaped then it is telocentric
So, the correct option is 'A-(ii),B-(iv),C-(i),D-(iii)'

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