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Addiction and dependence - class-XII

Description: addiction and dependence
Number of Questions: 76
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Tags: community health and hygiene human health and disease adolescence evs - i heredity and variation biology cell biology and biotechnology health and disease
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Organ which is most affected by alcohol is

  1. Heart

  2. Cerebrum

  3. Liver

  4. Cerebellum


Correct Option: C
Explanation:

Alcohol can cause inflammation in the liver. Over time, scarring and cirrhosis can occur. Alcoholic liver disease occurs after years of heavy drinking.
Thus, the correct answer is option (C), 'Liver'.

A factor responsible for cirrhosis of liver is

  1. Vitamins

  2. Fats and oils

  3. Alcoholism

  4. Sugar


Correct Option: C
Explanation:

Alcohol can cause inflammation in the liver. Over time, scarring and cirrhosis can occur. Alcoholic liver disease occurs after years of heavy drinking. Cirrhosis is the last step of liver damage
So, the correct answer is 'Alcoholism'

Addiction is

  1. Intake of drugs

  2. Intake of tobacco or alcohol 

  3. Physiological and psychological dependence

  4. Both A and B


Correct Option: D
Explanation:
Addiction is a condition in which a person becomes habitual or dependent for a particular substance or activities in which he finds pleasure. Substances like alcohol, drugs, nicotine (tobacco) cause the person to get addicted. With every dose, the body demands for more intake. Gambling activities also engage the person in such a way that he becomes addicted and in no such circumstances he can leave these activities even if social and personal life is being affected.
So, the correct answer is 'Both A and B'.

Excessive consumption of alcohol is

  1. Alcoholism

  2. Drug addiction

  3. Hallucination

  4. Intoxication


Correct Option: A
Explanation:
Alcoholism is the addiction of alcohol. It is dependency of a person on regular consumption of alcohol. Generally ethyl alcohol is consumed which can be in form of wine, bear etc. People suffering from alcoholism are obsessed with alcohol. Such people can't resist to drinking alcohol even if it is causing problems in their personal and professional life. Consumption of too much alcohol can cause serious health problems like liver failure.
So, the correct answer is 'Alcoholism'.

Bhang, Ganja and Hashish (Charas) are obtained from

  1. Rauwolfia

  2. Calotropis

  3. Cannabis sativa

  4. Withania


Correct Option: C

The symptoms of drug addiction is

  1. Restlessness

  2. Depression

  3. Anxiety

  4. All of the above


Correct Option: D
Explanation:
  • Drug addiction is a complex neurological disease that requires integrated treatment of the mind, body, and spirit. 
  • It is considered a brain disease because drugs change the brain they change its structure and how it works. Without treatment, these brain changes can be long-lasting. 
  •  Addiction is chronic, it is progressive, and if left untreated, it can be fatal.
Common signs of drug addiction include:
  1.  Loss of control 
  2. Serious changes or deterioration in hygiene or physical appearance
  3. Withdrawal symptoms such as shakiness, trembling, depression, nausea and fatigue are observed.
  •  Hence, The symptoms of drug addiction are restlessness, Depression and Anxiety. 
  • So, the correct answer is 'all of the above'.

Withdrawal symptom of alcohol/drug include
i) Anxiety        
ii) Shakiness 
iii) Nausea 
iv) Sweating

  1. i and ii

  2. i , ii and iv

  3. ii and iii

  4. i, ii, iii, iv


Correct Option: D
Explanation:

If a person who is having heavy dose of alcohol or drug suddenly stop or cut back on its consumption, it is called as alcohol or drug withdrawal. Mild withdrawal syndrome includes anxiety, shakiness, headache, nausea, vomiting, insomnia, sweating. The severe syndrome includes hallucination, seizures.

Thus, the correct answer is 'i, ii, iii, iv.'

Abrupt discotinuation of regular dose of drugs/ alcohol generates 

  1. Withdrawal syndrome

  2. Euphoria

  3. Mental stability

  4. Permanent feeling of well being


Correct Option: A
Explanation:

Abrupt discontinuation of regular does of drugs/ alcohol generates withdrawal syndrome. These are the set of symptoms which occurs due to abrupt discontinuation or dosage reduction of drug or alcohol. Withdrawal syndrome includes tremors, hallucination, vomiting, anxiety, sweating, irritability, insomnia.

Thus, the correct answer is 'Withdrawal syndrome.'

THC (tetra hydro cannabinol) is the active ingredient of all the following, except.

  1. Hashish

  2. Ganja

  3. Mescaline

  4. Marijuana


Correct Option: C
Explanation:
  • Hashish, ganja, and marijuana all three of this psychoactive drug obtained from the same plant ie Hemp ( Cannabis sativa).
  • Marijuana is the dried flower and the leaves of the female plant of cannabis. 
Hashish is also obtained from the cannabis plant but it is a more concentrated version of it. The Cannabis flower and leaves that fall off the plant are made into a ball and pressed with a knife and dried and then can be consumed orally or smoked.
  • Ganja is simply the leaves of the cannabis plants that are smoked.
All of the above three drugs have tetra hydro cannabinol as their active ingredients.
  • Mescaline is a hallucinogenic drug obtained from the plants of peyote cactus ( Lophophora Williams) with 3,4,5-trimethoxyphenethylamine as the active ingredient.

Therefore the correct answer is option C

Which of the following combination of drugs has a dramatic rapid increase in sedative effect?

  1. Alcohol $+$ Antihistamines

  2. Alcohol $+$ Benzodiazepines

  3. Alcohol $+$ Aspirin

  4. Amphetamine $+$ Insulin


Correct Option: B
Explanation:
Mixing drugs can have numerous detrimental effects. A common method of drug abuse involves mixing benzodiazepines with alcohol. They are abused together because both sedatives like benzodiazepines and alcohol are central nervous system depressants, using them together can cause excessive sedation.
So, the correct option is 'Alcohol + Benzodiazepines'.

Cannabinoid receptors present principally in the

  1. Heart

  2. Brain

  3. Liver

  4. Kidney


Correct Option: B
Explanation:

Cannabinoid receptors are those receptors which are mainly present in the brain but are also present in nearly all the organs of the body. They are the receptors that are responsible for the physiological functions as well as the functioning of the body. They are primarily found in the nervous system and brain region.

So, the correct option is 'Brain'.

In an epileptic patient,doctor administer a $GABA$ facilitatory  drug. After considerable time fits are absent in the patient.What would be the probable mechanism of that drug 

  1. It cause blocking of neurotransmitter at synaps and forms a complex

  2. It desensitize post synaptic membrane for neurotransmitter

  3. It inhibits $Na^+-K^+AT$ pase pump

  4. It cause hyperpolarisation of post synaptic membrane and generate IPSP


Correct Option: A
Explanation:
A GABA receptor agonist is a drug that is an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other effects such as anxiolytic, anticonvulsant, and muscle relaxant effects. 
So the correct option is 'It causes blocking of neurotransmitter at synapses and forms a complex'.

Drug that increases cardiovascular effects is?

  1. Nicotine $+$ Cocaine

  2. Benzodiazepine $+$ Barbitunate

  3. Barbiturates $+$ Novacaine

  4. Insulin $+$ amphetamine


Correct Option: A

Withdrawal symptoms of drug addiction are _________________.

  1. Showed during epilepsy

  2. Unpleasent symptoms shown due to non availability of addicted drugs

  3. Unpleasent symptoms showed due to alcoholism

  4. Unpleasent symptoms showed due to narcotic drugs


Correct Option: B
Explanation:
  • Addiction is a psychological and physical inability to stop consuming a chemical, drug, activity, or substance.
  • When a person has an addiction, and they stop taking the substance or engaging in the behaviour, they may experience symptoms. These symptoms include anxiety, irritability, tremors and shaking, nausea and vomiting, fatigue and a loss of appetite. 
  • Hence, Withdrawal symptoms of drug addiction are Unpleasant symptoms shown due to non-availability of addicted drugs. 
  • So, the correct answer is 'Unpleasant symptoms shown due to non-availability of addicted drugs'.

Anaemia in alcoholics may be due to deficiency of

  1. Vitamin A

  2. Vitamin D

  3. Folic acid and vitamin B$ _{12}$

  4. Vitamin C


Correct Option: C

The term 'Hot shot' is often used with respect to drug abuse through

  1. Injection

  2. Inhalation

  3. Drinking

  4. Shooting


Correct Option: A
Explanation:

Sometimes, an addict can get a sample of heroin, which is adulterated with a dangerous poison, strychnine. Its injection is known as 'hot shot', which can cause quick death. 'hot shot' can also occur, when an addict, used to injecting heroin 3-5% purity, gets a purer blend of the  drug.
Thus, the correct answer is option (A), 'Injection'.

In an alcohol addict

  1. The blood sugar level is low

  2. The blood sugar level is high

  3. The blood sugar level is normal

  4. The sugar absorption is impaired


Correct Option: B
Explanation:

Excessive alcohol consumption causes chronic inflammation of the pancreas i.e. pancreatitis, which impairs its ability to secrete insulin. Insulin is a hormone necessary for maintaining the normal concentration of glucose in the blood. It promotes the conversion of glucose to glycogen i.e. glycogenesis for storage in liver and muscle cells. Deficiency of insulin raises the blood sugar glucose and may lead to insulin-dependent diabetes mellitus. Thus the correct answer is option B.

The average cup of tea contains ........ mg of caffeine.

  1. 40

  2. 100

  3. 30

  4. 60


Correct Option: C
Explanation:

An average cup of tea contains approximately 20 - 30 mg of caffeine.

Initial stage of drug addiction is referred to as

  1. Tolerance

  2. Habituation

  3. Sleep

  4. Dependence


Correct Option: B
Explanation:

Habituation is becoming accustomed to any behaviors or condition, including psychoactive substance use. It is a desire but not a compulsion to continue taking the drug for the sense of improved well-being it engenders. This habituation is the initial stage of drug addiction,
Thus, the correct answer is option (B), 'Habituation'.

Cardiomyopathy is associated with

  1. Occassional alcohol consumption

  2. Moderate alcohol consumption

  3. Chronic alcohol consumption

  4. Insufficient alcohol consumption


Correct Option: C
Explanation:

Cardiomyopathy is a disease of abnormal heart muscle. The heart becomes enlarged ann it is harder for the heart to pump and deliver blood to the rest of the body. The excessive consumption of alcohol is one of the causes of cardiomyopathy.
So, the correct answer is option C.

Consumption of methanol can result in blindness; Since it

  1. Inhibits neurotransuitter GABA

  2. Is released from retina

  3. Generally damages optic nerve

  4. Is stored in cornea and tear glands


Correct Option: C
Explanation:

The consumption of methanol causes 'Toxic Optic Neuropathy' (TON). It is caused when the optic nerve is damaged by toxin which leads to visual impairment. This condition often presents as a painless, progressive, bilateral, symmetrical visual decline with variable optic nerve head damage. So, the correct answer is option C.

Continuous and excessive intake of alcohol causes

  1. Wernicke-Korsakoff syndrome

  2. Fatty liver 

  3. Cirrhosis and hypertension

  4. All of the above


Correct Option: D
Explanation:

Laenec syndrome is Laennec cirrhosis which is a disease of the liver in which the normal lobular architecture is lost.
Fatty liver syndrome is a reversible condition wherein large vacuoles of triglyceride fat accumulate in liver cells via the process of steatosis.
Cirrhosis is a stage of scarring/fibrosis of the liver caused by many liver diseases.
Thus, the correct answer is option (D), 'All of the above'.

Addiction to tobacco is mainly due to presence of

  1. Amphetamines

  2. Nicotine

  3. Tar

  4. None of the above


Correct Option: B
Explanation:

Nicotine is the primary addictive agent in cigarettes, chewing tobacco, cigars. Tobacco leads to nicotine dependence.
Thus, the correct answer is option (B), 'Nicotine.

Diacetylmorphine hydrochloride is 

  1. Heroin

  2. Brown sugar

  3. Methadone

  4. Both A and B


Correct Option: B
Explanation:
Diamorphine hydrochloride binds to opioid receptors in the central nervous system. It is a type of analgesic agent and a type of opiate. Also called diacetylmorphine hydrochloride and heroin. diacetylmorphine hydrochloride is also known as brown sugar.
So the correct option is B.

Impaired memory, lethargy, passivity, acute anxiety, depression and profuse sweating are symptoms associated with

  1. Alcoholism

  2. Drug addiction

  3. Mental illness

  4. All of the above


Correct Option: B
Explanation:

Drug addiction psychological symptoms include:

  • Unexplained change in personality or attitude
  • Sudden mood swings, irritability, or angry outbursts
  • Periods of hyperactivity, agitation or giddiness
  • Lack of motivation, appears lethargic
  • Appears fearful, anxious, or paranoid with no reason.
Thus, the correct answer is option B.

Peripheral vascular disease is most common in smokers which can lead to

  1. Gangrene

  2. Thrombosis

  3. Embolism

  4. All of the above


Correct Option: D
Explanation:

Peripheral vascular disease is commonly used to refer to peripheral artery disease, meaning narrowing or occlusion by atherosclerotic plaques of arteries outside of the heart and brain.
Risk factors for peripheral artery disease include elevated blood cholesterol, diabetes, hypertension and smoking. Complications of peripheral artery disease include sores that do not heal, ulcers, gangrene or infections in the extremities. A peripheral vascular disease that affects the veins include deep vein thrombosis, varicose veins. Pulmonary embolism is also caused by the blood clot due to peripheral vascular disease.
So, the correct answer is option D.

A person's reduced/diminished response to a drug is called

  1. Withdrawal

  2. Addiction

  3. Rebound effect

  4. Tolerance


Correct Option: D
Explanation:

Tolerance is the resistance of a person when addicted to a drug and can withstand even in higher doses. Hence, the correct option is D.

Assertion- Codeine causes addiction.
Reason- Codeine is an opium-derivative.

  1. Both Assertion and Reason are true and Reason is the correct explanation of Assertion.

  2. Both Assertion and Reason are true but Reason is not the correct explanation of Assertion.

  3. Assertion is true but Reason is false.

  4. Both Assertion and Reason are false.

  5. Assertion is false but Reason is true.


Correct Option: B
Explanation:

Codeine is a moderately strong opiate drug that is used in pain relief and for the suppression of coughs. But strong or weak, it is still an addictive drug with many symptoms of use in common with other opiates. The road to addiction to codeine usually starts with an increasing tolerance to the drug.
Therefore, the correct answer is option B.

Alcoholism leads to

  1. Amnesia

  2. Lung-damage

  3. Cancer

  4. None of the above


Correct Option: A
Explanation:

Alcoholism causes amnesia. The person drinks, does things and cannot remember them afterwards.

Essentially, amnesia is loss of memory. The memory can be either wholly or partially lost due to the extent of damage that was caused. There are two main types of amnesia, retrograde amnesia and anterograde amnesia.
Therefore, the correct answer is option A.

In alcoholics, liver gets damaged as it

  1. Accumulates excess of fats

  2. Stores excess of glycogen

  3. Secretes more bile

  4. Has to detoxify alcohol


Correct Option: A
Explanation:

Excessive alcohol causes fatty liver or steatosis. It describes the buildup of fats in the liver. It occurs when the body creates too much fat or cannot metabolize fat fast enough. As a result, the left over is stored in the liver cells where it accumulates to become fatty liver disease.
Therefore, the correct answer is option A.

Liver-cirrhosis is caused by

  1. Excess alcoholism

  2. No alcohol

  3. Due to bacterial infection

  4. Due to viral infection


Correct Option: A
Explanation:

Cirrhosis is an abnormal liver condition in which there is irreversible scarring of the liver. The main causes are sustained excessive alcohol consumption and fatty liver disease. Symptoms include loss of appetite, yellowing of the skin, fluid retention (oedema) and swelling in ankles, legs and abdomen. So, the correct answer is option A.

In the liver, alcohol is converted into which toxic substance?

  1. Formic acid

  2. Acetaldehyde

  3. Nicotine

  4. Urea


Correct Option: B
Explanation:

There are 2 ways that alcohol can be processed by your liver. Most alcohol is broken down, or metabolised, by an enzyme in your liver cells known as alcohol dehydrogenase (ADH). ADH breaks down alcohol into acetaldehyde and then another enzyme, aldehyde dehydrogenase (ALDH), rapidly breaks down acetaldehyde into acetate. The acetate is further metabolised and eventually leaves your body as carbon dioxide and water.

Acetaldehyde is a toxic substance that can cause an unpleasant reaction when it builds up. Symptoms you might experience if your ALDH enzyme does not function properly include flushing of the face, hot sensations, nausea and palpitations (an awareness of your heart beating faster than normal).
Therefore, the correct answer is option B.

Which of the following drug taken with alcohol may have dangerous effects?

  1. Morphin

  2. Opium

  3. Asprin

  4. None of the above


Correct Option: C
Explanation:

It is advised not to drink alcohol while taking aspirin. Alcohol can increase the risk of stomach bleeding caused by aspirin.
Therefore, the correct answer is option C.

Scopolamine or "truth drug" of world war II was obtained from

  1. Rauvolfia serpentina

  2. Atropa belladonna

  3. Digitalis purpurea

  4. Papaver somniferum


Correct Option: B
Explanation:

Scopolamine is an anticholinergic medicine. Scopolamine has many effects in the body including decreasing the secretion of fluids, slowing the stomach and intestines, and dilation of the pupils. Scopolamine is used to relieve nausea, vomiting, and dizziness associated with motion sickness and recovery from anesthesia and surgery. Scopolamine may also be used in the treatment of parkinsonism, spastic muscle states, irritable bowel syndrome, diverticulitis and other conditions. Scopolamine is also called as hyoscine. It is alkaloid drug obtained from a number of plants of the family Solenaceae, including nightshade (Atropa belladona), henbane and jimsonweed. 

Scopolamine is an effective remedy for motion sickness, probably because of its ability to depress the central nervous system. It is also known as a truth drug. Thus, option B is correct. 

In alchoholics, liver gets damaged as it

  1. Accumulates excess of fats

  2. Stores excess of glycogen

  3. Secretes more bile

  4. Has to detoxify alchohol


Correct Option: A
Explanation:

Abuse of alcohol may cause three types of liver damage, which often develop in the following order: Accumulation of fat (fatty liver, or steatosis): This type is the least serious and can sometimes be reversed. It occurs in more than 90% of people who drink too much alcohol

So the correct option is A.

Effects of alcohol on human body includes

  1. Increased blood sugar level

  2. Fatty liver syndrome

  3. Amnesia

  4. All of the above


Correct Option: D
Explanation:

Alcoholism causes amnesia. The person drinks, does things and cannot remember them afterwards.
Alcohol can cause blood glucose levels to rise or fall, depending on how much you drink.
Fatty liver syndrome results from the deposition of fats in liver cells resulting from the consumption of alcohol.
Therefore, the correct answer is option D.

Alcohol addiction is harmful because it causes

  1. Protein deposition in liver

  2. Deposition of extra fat in liver

  3. Rise in blood sugar level

  4. Cancer

  5. Both B and D


Correct Option: E
Explanation:

Alcoholism is a condition of taking excess alcohol at a time or frequently. This addiction can lead to damage to brain (like the mood change), heart ( strokes and high blood pressure), liver ( steatosis means excessive deposition of fat in the liver and causes fatty liver), and also causes cancer like throat, mouth and liver. Thus, the correct answer is option E.

Which of the following statements does not tell us about protecting ourselves from drug abuse?

  1. Avoid company of friends who take drugs.

  2. Acquire knowledge from parents and peers about drugs.

  3. Devote your time and energy to other extra curricular activities.

  4. Experiment with alcohol for fun and curiosity.


Correct Option: D
Explanation:

Friends can influence one to take drugs and alcohols. A person can protect himself against drug abuse by increasing ones will power to stay away from alcohol and drugs. One should not experiment with alcohol or drugs for curiosity and fun.

Identify the prominent adolescence disorder.

  1. Anxiety

  2. Dizzyness

  3. Depression

  4. Both A and C


Correct Option: D
Explanation:

Adolescence is marked by accelerated physical growth, development of reproductive organs and changes in functioning of the neuroendocrine system. It is observed that during adolescence, there is generally lack of sleep due to mood swings. Lack of sleep due to mood irregulation leads to Anxiety and Depression.

Thus, the correct answer is option D.

An adolescent is greatly influenced by __________ during this phase. 

  1. Parents

  2. Teachers

  3. Peer group

  4. None of the above


Correct Option: C

The study of the action of drugs is known as 

  1. Pharmacognosy

  2. Pharmacology

  3. Physiology

  4. Pharmaceutical chemistry


Correct Option: B
Explanation:

Pharmacology is the branch of the study of drug action, in which considers the site of action of drug, toxicity, side effects on plasma half life concentration, excretory by products, etc.

Drugs which induce dreamy state of consciousness is ______________.

  1. Sedative

  2. Stimulant

  3. Depressant

  4. Hallucinogen


Correct Option: D
Explanation:

 Hallucinogens cause optical illusion. Person loses all feelings of earthly existence of space and time.

So, the correct answer is 'Hallucinogen'

Dilation of blood vessels, increase in fat synthesis, low blood sugar and inflammation of stomach are due to the consumption of

  1. Tobacco

  2. Drug addiction

  3. Alcohol

  4. Tobacco and drug addiction


Correct Option: C
Explanation:

Long-term alcohol abuse poses great dangers to an alcoholic's physical, mental, emotional, social and spiritual health. In addition to serious ramifications for the user's career, family and friends, alcoholism can cause irreversible damage to critical organs and body systems such as dilation of blood vessels, an increase in fat synthesis, low blood sugar and inflammation of the stomach. So, the correct answer is option C.

The drug useful to increase cardiovascular effects in human beings is

  1. Cocaine

  2. Barbiturate

  3. Benzodiazepine

  4. Insulin


Correct Option: A
Explanation:

Cocaine is a powerful CNS( central nervous system) stimulant, which induces a sense of well-being and pleasure and delays fatigue. It causes lack of sleep, loss of appetite, headache, convulsions, insomnia, respiratory or cardiac failure and may lead to mental disorder.

Opium, morphine, heroin, pethidine and methadone are collectively called 

  1. Tranquillizers

  2. Stimulants

  3. Hallucinogens

  4. Opiate narcotics


Correct Option: D
Explanation:

Opiates are powerful painkillers and are made of opium, a white liquid in the poppy plant. Opiates produce a quick, intense feeling of pleasure followed by a sense of well-being and calm.
These include heroin, morphine, codeine, methadone, oxycontin etc.
Thus, the correct answer is option D.

Hallucinogens

  1. Are nerve depressants

  2. Are nerve stimulants

  3. Alter thoughts, feelings and perceptions

  4. Are pain relievers


Correct Option: C
Explanation:

Hallucinogens are drugs that generally produce dream-like state with disorientation and loss of contact with reality without any true sensory stimulus. These drugs change mood, behaviour, thoughts and perception in a manner like that of seen in psychosis. So, the correct answer is option C.

Marijuana is extracted from

  1. Dried leaves and flowers of hemp plant

  2. Ergot fungus

  3. Cocoa plant

  4. None of the above


Correct Option: A
Explanation:

The products of hemp plant, cannabis sativa like Marijuana, Bhang, Ganja, Charas (also called as 'Hashish' in some countries like America) etc., Tetrahydrocannabinol (THC) is present in hemp plant.

Cyclosporin A, an immunosuppressive drug is produced by

  1. Aspergillus niger

  2. Monascus purpureus

  3. Penicillium notatum

  4. Trichoderma polysporum


Correct Option: D
Explanation:

Cyclosporin is used as immuno depressant, this drug is derived from a fungus Trichoderma polysporum and inhibit the activity of helper - T cells, thus help to prevent rejection of organ transplant.

Which one is not a symptom of opium addiction?

  1. Slurred speech

  2. Slow respiration

  3. Dilation of pupil

  4. Drowsiness


Correct Option: C
Explanation:
Opiates are derived from opium which is dried latex of unripen capsular fruits of Papaver somniferum (poppy plant). It has bitter taste and heavy smell. It is eaten and smoked. The effects of opiates are analgesic, narcotic and sedative. They slow down respiration, impair digestion, cause constriction of pupil of eye, cause nausea and vomiting, poor pronunciation of words (slurred speech) and drowsiness or feeling of sleep.
Hence, dilation of pupil is not a symptom of opium addiction.
So, the correct answer is 'Dilation of pupil'.

Drugs that cause malformation in embryo during pregnancy are called as

  1. Tranquillizers

  2. Teratogens

  3. Alcoholic beverages

  4. Nicotin


Correct Option: B
Explanation:

Some drugs cause foetal abnormalities, when given to a pregnant women. These are called teratogens. The most well-known synthetic teratogen is thalidomide.

Which of the following, stimulates the heart?

  1. Mescaline

  2. Epinephrine

  3. LSD

  4. Hashish


Correct Option: B
Explanation:

Mescalin, LSD and hashish are hallucinogens and they affect the regions of the brain that are responsible for coordination, thought processes, hearing and sight.
Epinephrine is a hormone and a neurotransmitter. It binds to beta-adrenergic receptors on heart muscle cells. This causes the contraction rate of the heart to increase.
Thus, the correct answer is option B.

Ingestion of marijuana leads to illusions and alters the thoughts, feelings and perceptions of a person. Marijuana is a

  1. Narcotic

  2. Stimulant

  3. Hallucinogen

  4. Sedative


Correct Option: C
Explanation:

Marijuana is a hallucinogen that causes altered perception and feeling. They have powerful mind-altering effects and can affect the regions of the brain that are responsible for co-ordination, thought processes, hearing and sight.
Thus, the correct answer is option C.

Which of the following is an opiate narcotic?

  1. Barbiturates

  2. Morphine

  3. Amphetamines

  4. LSD


Correct Option: B
Explanation:

Opiates e.g., morphine, heroin, pethidine (meperidine), codeine and methadone have narcotic, analgesic, sedative and anti-stringent (that cause contraction of body parts) effects.

Charas of hasish is obtained from

  1. Leaves of Cannabis

  2. Resinuous secretion of flowering tops of female Cannabis

  3. Dried leaves of female Cannabis

  4. Resinuous secretion from bark of male plants of Cannabis


Correct Option: B
Explanation:
Hashish is a hallucinogenic drug prepared from resin secreted from flowering tops of Cannabis sativa (hemp). The resin is dried and pressed to form small blocks which are then smoked. It is a powerful hallucinogen which can change mood, behaviour and thoughts. It cause hallucinations and make false imaginations. It produces a dream like state and can even cause loss of contact with external reality.
So, the correct answer is 'Resinous secretion of flowering tops of female Cannabis'.

Assertion: Charas is a psychoactive drug.

Reason: Charas contains THC of 25 to 60%.

  1. If both assertion and reason are true and the reason is the correct explanation of the assertion.

  2. If both assertion and reason are true but reason is not the correct explanation of the assertion.

  3. If assertion is true but reason is false.

  4. If the assertion and reason both are false.

  5. If assertion is false but reason is true.


Correct Option: A
Explanation:
Answer is option A
Charas contains cannabinoids such as tetrahydrocannabinol (THC) in 25 to 60%. this allows Charas drug to have various psychological and physiological effects on the human body. Psyhological effect include emotional and psychological issues like apathy, a lack of motivation, depression, etc

Enzyme present in limited quantity in Asians for metabolism of alcohol is

  1. Alcohol dehydrogenase

  2. Succinate thiokinase

  3. Acetaldehyde dehydrogenase

  4. Both A and B


Correct Option: C
Explanation:
Acetaldehyde dehydrogenase is the enzyme which converts acetaldehyde into acetate. Acetaldehyde is produced from the metabolism of alcohol by the enzyme alcoholic dehydrogenase. Acetaldehyde is toxic and its accumulation can cause hangover so it needs to be metabolized. It is converted into acetate by aldehyde dehydrogenase. Acetate is then converted into carbon dioxide and water. About 50% people of northeast Asia have a dominant mutation in the gene encoding for enzyme aldehyde dehydrogenase resulteing in decreased activity of this enzyme. So, Asians have this enzyme in limited quantity.
So, the correct answer is 'Acetaldehyde dehydrogenase'.

In alcoholics, liver cells come to accumulate fat. Fat formation is stimulated by

  1. Alcohol

  2. Acetaldehyde

  3. Thiamine deciciency

  4. Folic acid deficiency


Correct Option: B
Explanation:
Alcohol is converted into acetaldehyde by alcoholic dehydrogenase. Consumption of too much alcohol affects liver and also cause hangover in which unpleasant physical and mental effects are seen due to accumulation of acetaldehyde. Acetaldehyde can lead to fatty liver syndrome because it stimulates the deposition of collagen in liver. This is called alcohol induced fibrosis. The cells of liver are replaced by fibrous tissue due to which liver hardens and dries up. This ultimately leads to liver failure.
So, the correct answer is 'Acetaldehyde'.

Hangover is

  1. Increased desire to take alcohol

  2. Feeling of giddiness and nausea in the morning after having taken alcohol

  3. Development of gastritis and peptic ulcers due to alcohol addiction

  4. Feeling of flushing after taking alcohol


Correct Option: B
Explanation:
Hangover is the experience of many unpleasant effects in body (which may be physiological or psychological) after consuming alcohol and occurs due to accumulation of acetaldehyde in the body. Acetaldehyde is formed from alcohol by the action of enzyme alcoholic dehydrogenase (ADH). It causes dizziness, dry mouth, headache weakness, mood changes etc. Other symptoms include anxiety, depression, nausea, vomiting, decreased sleep and sweating. These symptoms even last till morning when person wake up from the dizziness of alcohol consumed at night.
So, the correct answer is 'Feeling of giddiness and nausea in the morning after having taken alcohol'.

Use of Cannabis products results in

  1. Alteration in perception, thoughts and feelings

  2. Depressed brain activity and feeling of calmness

  3. Suppressed brain function and relief in pain

  4. Stimulation of nervous system, increased alertness and activity


Correct Option: A
Explanation:
Many hallucinogenic products are obtained from Cannabis plant such as Bhang, Ganja, Charas and Marijuana. These are obtained from different parts of Cannabis plant. For example, bhang is obtained from fresh and dried leaves and flowering shoots of both male and female plants. Hallucinogenic drugs are also called psychedelic drugs. They change thoughts, mood, behaviour and perceptions. 
So, the correct answer is 'Alteration in perception, thoughts and feelings'.

In alcoholics, urine is

  1. Hyperosmotic

  2. Isoosmotic

  3. Hypoosmotic

  4. Alkaline


Correct Option: A
Explanation:
In alcoholic persons, ADH (antidiuretic hormone) levels are decreased. ADH is secreted from posterior lobe of pituitary. It stimulates water reabsorption from kidneys and this results in decreased rate of urine production. Decreased secretion of ADH due to alcohol causes dehydration in body. The urine produced in body due to dehydration is hyperosmotic as its osmolarity is high due to deficiency of water.
So, the correct answer is 'Hyperosmotic'.

Hashish and Ganja are obtained from

  1. Erythroxylon

  2. Nicotiana

  3. Papaver

  4. Cannabis


Correct Option: D
Explanation:
Hashish and Ganja are hallucinogens obtained from Cannabis sativa (Hemp plant). Hashish is obtained from resin (the secreted gum) of Cannabis which is dried and pressed to convert it into a smokable form. Ganja is obtained from unfertilised female inflorescence. Hallucinogens are also known as psychedelic drugs. They change mood, behaviour and thoughts. They cause hallucinations and produce false imaginations.
So, the correct answer is 'Cannabis'.

Dipsomania is

  1. A type of depression

  2. Insanity due to psychosis

  3. Severe addiction to alcohol

  4. Tendency to take much water


Correct Option: C
Explanation:
Dipsomania is a condition in which there is uncontrolled craving for alcohol. Basically, dipsomania is alcoholism. People suffering from alcoholism are obsessed with alcohol. Such people can't resist to drinking alcohol even if it is causing problems in their personal and professional life. It can cause many serious health hazards like liver cirrhosis, loss of muscle coordination, reduced blood sugar level and dehydration.
So, the correct answer is 'Severe addiction to alcohol'.

Consumption of alcohol leads to

  1. Acetaldehyde accumulation in liver

  2. Fat synthesis in liver

  3. Lowering of blood glucose level

  4. All of the above


Correct Option: D
Explanation:
Consumption of alcohol leads to accumulation of acetaldehyde in liver which causes hangover. Unpleasant physical and mental effects occur in body due to hangover.
Alcohol consumption also leads to fatty liver syndrome in which there is build-up of fat in liver. Gradually the liver hardens and dries up. The healthy cells of liver are replaced by fibrous tissue. This leads to build up of scar tissue in liver and leads to cirrhosis.
Alcoholism reduces the level of sugar in blood and cause hypoglycaemia.
Hence, all options are correct. So, the correct answer is 'All of the above'.

With reference to Cannabis which is correct X,Y and Z?
Statement X: Flowers are attractive and produce scent.
Statement Y: Pollen grains are small, dry and light.
Statement Z: Cannabis is wind pollinated plant.

  1. X and Y are wrong, Z is independent of X and Y

  2. X is wrong, Y is correct and Z is correct reason for Y

  3. X is correct, Y is wrong and Z is correct reason for X

  4. Both X and Y are correct, Z is correct reason for Y


Correct Option: B
Explanation:
Cannabis is an annual herb which is indigenous to eastern Asia. Many hallucinogenic drugs like bhang, charas and marijuana are obtained from different parts of Cannabis plant. The flowers of Cannabis plant are wind pollinated so they have small, dry and light pollen grains which can be easily carried by the wind to the stigma of another flower. The flowers are not attractive and do not produce any scent because scented flowers are characteristics of insect pollinated plants.
Hence, statement X is wrong and both Y and Z are correct with Z being the correct reason for Y.
So, the correct answer is 'X is wrong, Y is correct and Z is correct reason for Y'.

Every time when the dosage of drug has to be increased to achieve the same kick, that initially occurred in response to a smaller dose, the condition is known as

  1. Addiction

  2. Tolerance

  3. Withdrawal symptom

  4. Rebound effect


Correct Option: B
Explanation:
Tolerance is the condition in which the body gets used to drugs due to drug addiction and the person's reaction to drugs get reduced. To get the same effect, body needs more dosage of drugs. This happens every time dosage is increased because after taking drugs regularly, at some point of time body gets used to the dosage and produce no reactions. There is uncontrolled craving for taking increased dosage of drugs when the person doesn't get desired effects with the present dose. 
So, the correct answer is 'Tolerance'.

In liver, alcohol is converted into a more toxic substance called

  1. Acetaldehyde

  2. Formaldehyde

  3. Hydrogen cyanide

  4. Methane


Correct Option: A
Explanation:
In liver, alcohol is converted to acetaldehyde by the enzyme alcoholic dehydrogenase. Acetaldehyde is more toxic than alcohol and its accumulation can cause hangover symptoms in which unpleasant mental and physical experiences occur in body. It can alter various functions of liver by binding to different proteins. Formation of adduct of acetaldehyde affects activity of various enzymes. It may also cause dizziness and skin reactions too.
So, the correct answer is 'Acetaldehyde'.

The secondary metabolite obtained from Catharanthus roseus is

  1. Vincristine

  2. Anthocyanin

  3. Menthol

  4. Nicotine.


Correct Option: A

Consider the following plants.
a. Cannabis
b. Leucaena leucocephala
c. Morux albci
d. Cocos nucifera
Among these the one(s) which can be called multipurpose plant(s) would include.

  1. $4$ alone

  2. $1, 2$ and $3$

  3. $1, 2$ and $4$

  4. $1, 2, 3$ and $4$


Correct Option: A

Canabis sativa is the source of

  1. Opium

  2. LSD

  3. Marijuana

  4. Cocaine


Correct Option: C
Explanation:

Cannabis sativa is a species of plant from the family cannabaceae. It is a psychoactive drug that can be used for medicinal or recreational purpose. So, the correct option is 'marijuana'.

The most specific indication in case of cirrhosis of liver cells is the increase in the level of which enzyme?

  1. CoA

  2. SGPT

  3. LDH

  4. CPK


Correct Option: B
Explanation:

Alanine aminotransferase (ALT) or serum glutamate pyruvate aminotransferase (SGPT) is the enzyme produced by liver cells. It helps the body metabolize proteins. Cirrhosis is the disease in which normal liver cells are replaced by scar tissue caused by alcohol and viral hepatitis B and C. If the liver is damaged as in cirrhosis, SGPT is released into the blood and this causes SGPT levels to increase.
Thus, the correct answer is option (B), 'SGPT'.

The tobacco protein induced arteriosclerotic disease is

  1. Aneurysm

  2. Polyarteritis nodosa

  3. Thromboangiitis obliterans

  4. DVT


Correct Option: C
Explanation:

Thromboangiitis obliterans, also called Buerger disease is a rare disease caused by small blood vessels that become inflamed and swollen. The blood vessels, then narrow or become completely blocked by the blood clots (Thrombosis). Blood vessels of the hand and feet are especially affected. This condition mostly affects young men, ages, 20-40, who are heavy smokers or chew tobacco.
Thus, the correct answer is option (A), 'Thromboangiitis obliterans'

The organ which is most affected by alcohol, is

  1. Liver

  2. Cerebrum

  3. Cerebellum

  4. Heart


Correct Option: A
Explanation:

The liver is the organ that is the most affected due to alcohol as the alcohol is processed in the liver and affects it adversely.

So the correct option is A.

Which cell organelle plays an important role in detroxification of many poisons and drugs in a cell ?

  1. mitochondria

  2. vacuoles

  3. Iysosomes

  4. smooth endoplasmic reticulum


Correct Option: D
Explanation:

The endoplasmic reticulum functions as a cytoplasmic framework providing a surface for some of the biochemical activities of the for some of the biochemical activities of the cell. In the liver cells of vertegrates, smooth endoplasmic reticulum (SEF) plsys a crucial role in detoxifying many poisons and drugs.

Drug addict shows symptoms of depressed brain activity, feeling of calmness, relaxation, drowsiness. Possible the addiction is of

  1. Valium

  2. Amphetamine

  3. Morphine/pethidine

  4. Marijuana/hashish


Correct Option: A
Explanation:
Valium (diazepam) is a benzodiazepine prescribed for the treatment of anxiety, seizures, muscle spasms, and symptoms of alcohol withdrawal. Valium is available as a generic drug. Common side effects of Valium include:
drowsiness, tired feeling, dizziness, spinning sensation, fatigue, constipation,
ataxia (loss of balance), memory problems, restlessness, irritability, muscle weakness, nausea, drooling, dry mouth, slurred speech, blurred or double vision, skin rash, itching, or loss of interest in sex.
So the correct answer is 'Valium'.

Antihistamines interact with alcohol and cause marked drowsiness.

  1. True

  2. False


Correct Option: A
Explanation:
Antihistamines interact with alcohol and cause marked drowsiness. It’s best to avoid mixing alcohol and antihistamines, as they both depress the central nervous system, thereby impairing the ability to coordinate physical motor movements and remain awake and conscious. 
So, the correct option is 'True'

Which of the following options are CORRECT?

$1$. Heroin Stimulant
$2$. Marijuana Cardiovascular
$3$. Cocaine Hallucinations
$4$. Morphine Sedative


  1. $1, 2$ and $3$

  2. $1, 3$ and $4$

  3. $2, 3$ and $4$

  4. $1, 2$ and $4$


Correct Option: C
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