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Blood group - class-XII

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Which of the following cells play an important role in failure of transplanted organ?

  1. $CD _4$ cells and $CD _8$ cells

  2. Natural killer cells

  3. Plasma cells

  4. Mast cells


Correct Option: A

The possible blood groups of children born to parents having A and AB blood groups are?

  1. O, A

  2. O, A, B

  3. A, B, AB

  4. O, A, B, AB


Correct Option: A

Antibody common to blood group $O^-$ and individual with blood group $B^+$ is /are 

  1. Anti -B

  2. Anti A

  3. Both Anti B and Anti A

  4. Anti -RH


Correct Option: A

Persons with blood group A possess

  1. Antigen A and antibodies b

  2. Antigen A and antibodies a

  3. No antigen but antibodies a and b

  4. Antigens A and B but no antibodies.


Correct Option: A

A man with blood group AB' marries a woman withO' blood group. In this situation

  1. The blood groups of their children will be the same as that of the mother

  2. The blood group of the children differs from both the parents

  3. While 50% of children will have father's blood group, the remaining will have mother's blood group

  4. None of the above


Correct Option: B
Explanation:

When a man with blood group "AB" marries a woman with "0" blood group then blood group of children will be A' orB' which is differ from parental blood group. 

Parents belong to blood group A and B. Blood group of their child would be

  1. A or B

  2. O

  3. AB

  4. All the above.


Correct Option: D

A child of blood group O cannot have parents of blood groups

  1. AB and AB/O

  2. A and B

  3. B and B

  4. O and O.


Correct Option: A

Blood transfusion is possible between groups

  1. Donor A and recipient O

  2. Donor B and recipient A

  3. Donor AB and recipient O

  4. Donor AB and recipient AB


Correct Option: D

What cannot be the blood groups of the parents of a baby having blood group A?

  1. O and O

  2. O and A

  3. A and O

  4. A and A.


Correct Option: A

A woman with blood group O marries a man of AB blood group. The blood group of their child would be

  1. AB and O

  2. A or B

  3. AB

  4. O.


Correct Option: B

Which of the following genotypes have blood group B?

  1. A/B, +/+

  2. A/A, +/A

  3. +/+, +/+

  4. B/B, +/B.


Correct Option: D

O blood group is universal donor because the blood has

  1. Antigen A

  2. Antigen B

  3. Both antigens A and B

  4. No antigens.


Correct Option: D

A blood group does not have any antigen but possesses both a and b antibodies. It is

  1. A

  2. O

  3. B

  4. AB.


Correct Option: B

Blood group A has

  1. Antibody a on RBC

  2. Antibody a in plasma

  3. Antigen A on RBC

  4. Antigen A in plasma.


Correct Option: C

A child has blood group B. Mother has blood group A. The blood group of the father would be

  1. O

  2. O or A

  3. B or AB

  4. A.


Correct Option: C

In ABO system of blood grouping, transfusion is not possible from

  1. A to AB

  2. B to AB

  3. O to AB

  4. A to O.


Correct Option: D

The genotype of B-group father of an O-group child is

  1. $I^O I^O$

  2. $I^B I^B$

  3. $I^A I^B$

  4. $I^O I^B$.


Correct Option: D

Which of the following chemicals can be used as anticoagulant?

  1. Sodium chloride

  2. Sodium citrate

  3. Sodium nitrate

  4. Ammonium chloride.


Correct Option: B

Husband and wife should know their Rh factors because the situation can be serious due to biological incompatibility in one of the following cases

  1. $Rh^+$ husband and $Rh^+$ wife

  2. $Rh^-$ husband and $Rh^-$ wife

  3. $Rh^-$ husband and $Rh^+$ wife

  4. $Rh^+$ husband and $Rh^-$ wife.


Correct Option: D

In case of emergency (e.g., serious accident with great blood loss) which blood group could be safely transfused

  1. AB $Rh^-$

  2. O $Rh^+$

  3. AB $Rh^+$

  4. O $Rh^-$.


Correct Option: D

A man with blood group A marries AB blood group woman. Which type of progeny indicate that the man is not homozygous?

  1. AB

  2. B

  3. A

  4. O.


Correct Option: B

Person with AB blood group can

  1. Not receive universally

  2. Universally donate

  3. Universally receive

  4. Receive only from O.


Correct Option: C

Parents with blood groups O and AB cannot have AB child as

  1. Gene for O is dominant over gene for B

  2. Gene for O is dominant over gene for A

  3. Genes for A and B are absent in one of the parents

  4. Gene for A or B is absent in one of the parents.


Correct Option: C

Which one is the common anticoagulant used for preserving blood?

  1. Sodium hydroxide

  2. Sodium chloride

  3. Sodium oxalate

  4. Sodium bicarbonate.


Correct Option: C

Donor X and recipient Y belong to same blood group. Transfusion has led to RBC agglutination because

  1. X is $Rh^+$, Y is $Rh^-$

  2. X is $Rh^-$, Y is $Rh^+$

  3. Both are $Rh^+$

  4. Both are $Rh^-$.


Correct Option: A

$Rh^-$ mother carries $Rh^+$ foetus. The foetus is at risk of disease called

  1. Haemophilia

  2. Haemolytic disease

  3. Tuberculosis

  4. Syphilis.


Correct Option: B

Rh factor occurs in

  1. All reptiles

  2. Man and Rhesus Monkey

  3. All mammals

  4. All vertebrates.


Correct Option: B

A sample of blood shows clumping with antiserum A but not with antiserum B. The blood group would be

  1. O

  2. A

  3. B

  4. AB.


Correct Option: B

Blood group B means the person

  1. Can form antibody for B

  2. Cannot form antibody for B

  3. Can receive blood of AB group

  4. Cannot receive blood group O.


Correct Option: B

Problem related to Rh factor arias when $Rh^+$ and $Rh^-$ bloods mix up

  1. In test tube

  2. Through transfusion

  3. Through pregnancy

  4. Both A and C.


Correct Option: B

Person with AB blood group can receive blood from

  1. AB only

  2. O only

  3. Both A and B

  4. All the above.


Correct Option: D

In which of the following situations, there is risk of erythroblastosis foetalis

  1. Mother $Rh^+$, father $Rh^+$

  2. Mother $Rh^-$, father $Rh^-$

  3. Mother $Rh^-$, father $Rh^+$

  4. Mother $Rh^+$, father $Rh^-$.


Correct Option: C

Which one is not a blood group

  1. ABO and Rh

  2. Rh and MN

  3. Buffs and Kips

  4. Lewis and Duffy.


Correct Option: C

Blood corpuscles containing both A and B antigens are mixed with another blood serum. The blood corpuscles agglutinated. Blood serum belongs to blood group

  1. A

  2. B

  3. AB

  4. O.


Correct Option: D

For safe blood transfusion

  1. Donor's RBC should not contain antibodies against recipient's serum

  2. Recipient's serum should not contain antigens against donor's antibodies

  3. Recipient's serum should not contain antibodies against RBC of donors

  4. Recipient's RBC should not contain antibodies against donor's antigens.


Correct Option: C

A mismatch during transfusion of blood causes

  1. Agglutination

  2. Erythroblastosis

  3. Haemopoies

  4. None of the above.


Correct Option: A

Assertion. Blood group 'O' has both anti-A and anti-B antibodies
Reason. It does not have any antigen

  1. A

  2. B

  3. C

  4. D.


Correct Option: B

Rh factor occurs in

  1. All vertebrates

  2. All reptiles

  3. All mammals

  4. Man and Rhesus monkey only.


Correct Option: D

Which blood transfusion is correct?

  1. A $\rightarrow$ B

  2. B $\rightarrow$ A

  3. AB $\rightarrow$ A

  4. O $\rightarrow$ B.


Correct Option: D

Blood group agglutinogen is

  1. Phosphoprotein

  2. Glycoprotein

  3. Haemoprotein

  4. Phospholipid.


Correct Option: B

Haemolytic disease of new born due to Rh incompatibility is

  1. Erythroblastosis foetalis

  2. Hydrops foetalis

  3. Kernicterus

  4. All the above.


Correct Option: A

If the foetus is Rh (+) ve and the mother is Rh (-) ve, then

  1. Foetus will transmit blood toxin to mother

  2. Foetus will transmit antibody to mother's blood

  3. Foetus is attacked by antibodies of mother's blood

  4. Foetus is attacked by antigen of mother's blood


Correct Option: C

What is true of blood group B

  1. The person can form antibody b

  2. The person cannot form antibody b

  3. The person cannot be given blood of 'O' group

  4. The person can receive blood of AB group.


Correct Option: B

The natural antibodies in the plasma of a person with blood group 'O' is

  1. anti-A

  2. anti-B

  3. anti-A and anti-B

  4. anti-B and anti-D

  5. anti-D.


Correct Option: C

Clumping of RBC may occur when blood of one person is mixed with serum or blood of another person. This is due to

  1. Antigen-antibody reaction

  2. Antitoxin-antibody reaction

  3. Antigen-antigen reaction

  4. Antibody-antibody reaction


Correct Option: A
Explanation:

The RBC membrane contains either antigen A or antigen B, or both Antigen A and B or no antigen at all, accordingly the blood is classified as blood group A , B , AB and O respectively. The blood plasma of blood group A will have antibodies for B, that of B will have antibodies for A,  that of AB will have non, while that of O will have both the antibodies. If blood is transfused at random this will lead to antigen-antibody reaction - like if A is the blood group of the recipient while the blood group of the donor happens to be B, this will lead to clumping of the RBCs.

So, the correct answer is 'Antigen-antibody reaction'

Anti-A and Anti-B antibodies are not found in which of the following blood group?

  1. AB

  2. A

  3. O

  4. B


Correct Option: A
Explanation:

The cell membrane of RBCs in AB blood group contain both antigen A as well as antigen B therefore the blood plasma does not contain antibody A and Antibody B, to prevent the coagulation of blood cells due to antigen-antibody reactions.

So, the correct answer is 'AB'

A boy has the blood group 0. What is true of the inheritance of this blood group in his case?

  1. His mother should be with AB blood group

  2. Both his parents could be heterozygous A group

  3. His father could be homozygous B group

  4. His mother could be homozygous A group


Correct Option: B
Explanation:

If the boy has blood group o, both his parents could probably be heterozygous A group, $I^AI^O$, in both the parents.

So, the correct option is 'Both his parents could be heterozygous A group'.

Rh factor was discovered by

  1. Landsteiner and Weiner

  2. William Harvey

  3. Malpighi

  4. None of these


Correct Option: A
Explanation:

Rh factor is an independent antigen present on the RBC irrespective of the presence of Antigen A or B. This factor is passed down from genus Rhesus macaque  (monkey) to humans and is regarded as the Rh factor it was discovered by Landsteiner and Weiner.

so, the correct answer is 'Landsteiner and Weiner'

Genotype of human blood group 'O' will be ______________.

  1. $I^A I^A$

  2. $I^A I^B$

  3. ii

  4. $I^A i$


Correct Option: A

A child's blood group is `O'. The parents blood groups cannot be

  1. AB and 0

  2. B and 0

  3. A and B

  4. A and A


Correct Option: A

A woman of blood group O' presented a baby of blood groupO' which she claimed as her child. She brought a suit against a man of 'AB' group as the father of the child. 

Which statement is correct as per your judgement

  1. The father and mother claimed are the true persons

  2. Father is true and mother is not the true person

  3. Both the parentage claims are false

  4. Mother is the true person and father claimed is not true


Correct Option: D

Antigen - A andantibody - B are present in which blood group

  1. B

  2. A

  3. AB

  4. 0


Correct Option: B

In a medico-legal case of accidental interchange between two babies in a hospital, the baby of blood group A could not be rightly given to a people

  1. With both husband and wife of group 0

  2. Husband of group 0 and wife of group A

  3. Husband of group A and wife of group 0

  4. Both husband and wife of group A


Correct Option: A

Which blood group called as universal donar?

  1. $AB$

  2. $A$

  3. $B$

  4. $O$


Correct Option: D
Explanation:

Type O ( specifically O negative ) blood is called the universal donor type because it is compatible with any blood type. O blood group does not contain any antigen hence does not result in transfusion reactions.


So, the correct option is 'O'.

Between persons of which two blood groups is the blood transfusion not possible

  1. 0 and AB (AB recipient)

  2. 0 and A (0 donor)

  3. 0 and B (0 donor)

  4. 0 and AB (AB donor)


Correct Option: D
Explanation:

The people of blood group AB can receive transfusions of blood from people of any of the four blood groups, are called universal recipients.

Which is true of blood group agglutination test?

  1. Blood group AB when coagulation occurs with antiserum A

  2. Blood group B when coagulation occurs with antiserum B

  3. Blood group O when coagulation occurs with antiserum A as well as B

  4. None of the above.


Correct Option: B

One intern calculated the concentration of $O _2$ in blood as 0.0025 ml/ml of blood. Considering atmospheric pressure as 760 mmHg, how much approx. $O _2$ tension could have been in the blood?

  1. 40mmHg

  2. 60mmHg

  3. 80mmHg

  4. 100mmHg


Correct Option: A

Choose the correct answer from the alternatives given.
Which of the following is an example of codominance?

  1. Pink flowers of snapdragon

  2. The ABO blood groups in humans

  3. Sex-linkage in humans

  4. None of these


Correct Option: B
Explanation:
  • Pink flowers of Snapdragon is a heterozygote phenotype and an intermediate phenotype of the two homozygous phenotypes from which it originates. It is an example of incomplete dominance.
  • Codominance is seen when both the alleles are expressed simultaneously and neither of the alleles is dominant over the other. In human ABO blood grouping system both the alleles I$^A$ and I$^B$ are codominant and hence in the AB blood group individuals both the antigens, A and B are seen. So, the human ABO blood grouping is an example of codominance.
  • The expression of the sex chromosomes in humans differ in males and females and hence are said to be sex-linked.
So, the correct option is 'The ABO blood groups in humans'.
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