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Digestive system of human - class-XII

Description: digestive system of human
Number of Questions: 40
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Tags: digestive system of human digestion and absorption biology
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Digestion of protein takes place in

  1. Duodenum and stomach

  2. Stomach and oesophagus

  3. Small and large intestine

  4. Intestine and rectum


Correct Option: A

Which of the following is incorrect regarding the given digestion and absorption of protein?

  1. The breakdown of proteins to peptides is catalyzed by pepsin in the stomach and by the pancreatic enzymes trypsin and chymotrypsin in the small intestine.

  2. Peptides are broken down into amino acids by pancreatic carboxypeptidase and intestinal aminopeptidase.

  3. Small peptides consisting of two or three amino acids can diffuse through the epithelial cell and broken down into carbon dioxide and ammonia which are released into the blood.

  4. None of these


Correct Option: B
Explanation:

  • Digestion of protein is initiated in the stomach by the enzyme pepsin.
  • In the small intestine, further digestion is done by trypsin, chymotrypsin, and carboxypeptidase into dipeptidase that releases from the pancreas.
  • Dipeptidase are broken into amino acids by intestinal dipeptidase.
  • These amino acids are absorbed actively by walls of intestine and release in the bloodstream.
  • These are utilized by tissues and broken down into carbon dioxide and ammonia.
  • Proteins require maximum energy to digest.

So the correct option is 'Peptides are broken down into amino acids by pancreatic carboxypeptidase and intestinal aminopeptidase.'

How does pepsinogen change into its active form?

  1. In the presence of hydrochloric acid

  2. In the presence of trypsin

  3. In the presence of  bile

  4. In the presence of carboxypeptidae


Correct Option: A
Explanation:

 Parietal cells of stomach secrets hydrochloric acid which convert inactive pepsinogen to partially active pepsinogen, partially activates pepsinogen then cleaves the peptide from other pepsinogen molecules to form active pepsin which converts protein into proteases and peptides.

So, the correct answer is 'In the presence of hydrochloric acid'.

Which of the following is the correct matching of the site of action on the given substrate, the enzyme acting upon it and the end product?
(i) Small intestine: Protein $\xrightarrow{Pepsin}$ Amino acid
(ii) Stomach : Fat $\xrightarrow{Lipase}$ Micelles
(iii) Duodenum : Triglycerides $\xrightarrow{Trypsin}$ Monoglyceride 
(iv) Buccal cavity : Starch $\xrightarrow{Amylase}$ Disaccharide
(v) Jejunum: Peptones $\xrightarrow{Pepsin}$ Amino acid
(vi) Buccal cavity : Starch $\xrightarrow{Amyloglycerate}$ Maltose

  1. (i),(ii) and (iii) are correct

  2. (iv) only 

  3. (iv) and (v) are correct

  4. All are correct


Correct Option: B
Explanation:

(i) Pepsin digest protein in the stomach.

(ii)Lipase digest emulsified fat in the intestine.
(iii)In duodenum trypsin digest protein or dipeptides.
(iv) Starch is digested into maltose by salivary amylase in the buccal cavity.
(v)Pepsin digest protein in the stomach.
(vi) Starch is digested into maltose by salivary amylase in the buccal cavity.
So the correct option is '(iv) only '

Read the given statements and select the option that correctly identifies them as true or false
1) Insulin has no effect on absorption of glucose from gastrointestinal tract
2) Fat absorption is greatest in the upper part of the small intestine
3) most vitamins are absorbed in the ileum

  1. True

  2. False


Correct Option: A
Explanation:
1) Insulin has no effect on the absorption of glucose from the gastrointestinal tract as it increases the amount of glucose absorption when its concentration increase in blood.
2) Fat absorption is greatest in the upper part of the small intestine because in duodenum bile emulsifies it and form micelles which are absorbed form.
3) Most vitamins are absorbed in the ileum.
So the correct option is 'True'.

What is common among amylase, renin and trypsin?

  1. They are proteins

  2. All these are proteolytic enzymes

  3. These are produced in stomach

  4. These act at the pH of less than 7


Correct Option: A
Explanation:

A) Amylase is produced by buccal cavity, pancreas and intestine and digest starch.

B) Renin is produced by the stomach and helps in the digestion of milk in infants.
C) Trypsin is produced by the pancreas and helps in the digestion of protein.
But one thing is common in all the above three is that they are made up of proteins.
So, the correct option is 'They are proteins'.

If PH of stomach is made 7, which component of the food would be affected?

  1. Starch

  2. Proteins

  3. Fat

  4. Sucrose


Correct Option: B
Explanation:

If pH of the stomach is made 7 protein digestion will affect as pepsin works ar pH of 2 to 3 and enzymes are highly precise about there function so it does not activate.

So the correct option is 'proteins'.

Chief function of HCl is ________

  1. To maintain a low pH to promote growth of microorganism

  2. To facilitate absorption

  3. To maintain low pH to activate pepsinogen to form pepsin

  4. To dissolve enzyme secreted in stomach


Correct Option: C
Explanation:

The chief function of HCl in the stomatch is to maintain low pH to activate pepsinogen to form pepsin. HCl converts inactive pepsinogen into the active pepsin enzyme. The pepsin helps in the breaking down proteins in the stomach. HCl also kills bacteria that enter the stomach. It also helps in digestion of  other foods in the stomach.

Thus, the correct answer is 'To maintain low pH to activate pepsinogen to form pepsin.'

Which of the following statements are correct about the function of the acidic environment of the stomach?
(i) Provides defence against bacteria entering the digestive system
(ii) Converts pepsinogen to pepsin
(iii) Assists the breakdown of cells in animal and plant food stuffs

  1. ii only

  2. i and ii only

  3. ii and iii only

  4. i, ii, and iii


Correct Option: B
Explanation:

The HCl is secreted by the oxyntic cells in the stomach. The HCl provides the acidic medium in the stomach that is responsible for converting the inactive pepsinogen to the active pepsin. Pepsin is required for protein digestion. The acidic medium provides defence against bacteria entering the digestive system.

Hence, the correct answer is 'i and ii only'

Which of the following enzymes is not useful in the digestion of proteins?

  1. Chymotrypsin

  2. Pepsin

  3. Trypsin

  4. Lipase


Correct Option: D
Explanation:
  • Protein digestion occurs in the stomach and duodenum in which 3 main enzymes: Pepsin, trypsin and chymotrypsin.
  •  pepsin secreted by the stomach and trypsin and chymotrypsin secreted by the pancreas, break down food proteins into polypeptides that are then broken down by various exopeptidases and dipeptidases into amino acids. 
  • Hence, Lipase enzymes are not useful in the digestion of proteins.
  • So, the correct answer is 'Lipase'.

Where are proteins first digested in the alimentary canal?

  1. Small intestine

  2. Oesophagus

  3. Mouth

  4. Stomach


Correct Option: D
Explanation:

The digestion of the food starts at the mouth where the enzyme amylase is secreted which digests the start that is present in the food and converts it into maltose. From there through the esophagus the food arrives in the stomach where it is stored for 4 hours and mixed with acid. The food when arrives at the stomach where the wall of the stomach secrets HCl with a pH of 1.8. This acid activates the inactive pepsinogen enzyme and forms active pepsin which digests proteins and converts them into proteases and peptides. From here the food moves to the small intestine where secretion from the liver and pancreas reach through a hepatopancreatic duct which is alkaline in nature and neutralizes the acidic food that comes from the stomach. Here majority of the digestion of protein to amino acids, fat to fat droplets, polysaccharides to monosaccharides etc takes place.


Therefore the correct answer is option D 

In the stomach proteins are hydrolysed by enzyme pepsin and $H^+$ to give-

  1. Peptones

  2. Proteoses

  3. Polypeptides

  4. $\alpha-$amino acids


Correct Option: A
Explanation:

In the stomach, proteins are hydrolysed by enzyme pepsin. It begins the digestion of proteins by splitting them into peptones (see peptidase). It is produced by the action of $HCl\left( { H }^{ + } \right) $ on pepsinogen, which is secreted by the stomach in gastric glands.

Which of these will leave the stomach first in man?

  1. Beer

  2. Proteins

  3. Fats

  4. Carbohydrates


Correct Option: A
Explanation:

Only some chemicals medicines and alcohol are absorbed in oro pharyngeal cavity. In the stomach, absorption of water, some salts, alcohol and glucose takes place, complete absorption of alcohol takes place in the stomach. Thus, carbohydrates, proteins and fats will remain in alimentary canal for complete digestion and when broken down completely in small intestine then only they will be absorbed in the intestine but beer will not be digested in alimentary canal and directly absorbed in the stomach.

The type of food which starts digesting in stomach is

  1. Fats

  2. Carbohydrate

  3. Protein

  4. All of the above


Correct Option: C
Explanation:

Carbohydrate digestion starts in the mouth as salivary amylase is present there. Protein digestion starts in the stomach as protein digesting enzymes is present in stomach and fat digestion occurs in the small intestine.

Rennin is found in  

  1. Liver

  2. Kidney

  3. Pancreatic juice

  4. Gastric juice in stomach


Correct Option: D
Explanation:

Rennin is a milk-curdling enzyme, that occurs in the gastric juices of infants and is also contained in the rennet produced in the stomach of calves and other ruminants. It is an endopeptidase, that converts casein to paracasein and was formerly used extensively as a curdling agent by the cheese industry. 

Main function of HCl in stomach is to

  1. Activates amylase enzyme

  2. Facilitate absorption of food

  3. Dissolve enzymes

  4. Activate pepsinogen to pepsin


Correct Option: D
Explanation:

Stomach in vertebrates is the main site for digestion of proteins. Pepsin is the chief proteolytic enzyme of stomach secreted in the inactive form called as pepsinogen. The pepsinogen is activated to pepsin in presence of hydrochloric acid secreted in stomach by oxyntic or parietal cells. The optimum pH for activity of pepsin is 1.8.

Therefore, the correct answer is option D.

If the stomach did not produce any hydrochloric acid, which enzyme will not function?

  1. Ptyalin

  2. Trypsin

  3. Pepsin

  4. Collagenase


Correct Option: C
Explanation:

Hydrochloric acid (HCl) converts pepsinogen to pepsin which breaks down proteins to peptides. HCl maintains a pH in the stomach of approximately 2.0. It also dissolves food and kills microorganisms. Without enough HCl, pepsinogen is no converted to pepsin which do not allow the breakdown of proteins

So, the correct answer is 'Pepsin'

Stomach in vertebrates is the main site for digestion of 

  1. Proteins

  2. Carbohydrates

  3. Fats

  4. Nucleic acids


Correct Option: A
Explanation:

Stomach in vertebrates is the main site for digestion of proteins. Pepsin is the chief proteolytic enzyme of stomach secreted in the inactive form called as pepsinogen. The pepsinogen is activated to pepsin in presence of hydrochloric acid secreted in stomach by oxyntic or parietal cells. The optimum pH for activity of pepsin is 1.8.

A man sits down to eat a large steak. Concerned about heartburn, he takes several antacid tablets before eating so as to neutralize his stomach acid.
Which of the following may result from this action?

  1. Increased chemical digestion of the protein in the steak by the stomach.

  2. Decreased absorption of the protein in the steak by the small intestines.

  3. An increase in the peristaltic actions of the mans digestive tract.

  4. Increased urine production by the man's kidneys.


Correct Option: B
Explanation:
  • Digestion typically begins in the stomach when pepsinogen is converted to pepsin by the action of hydrochloric acid. And continued by trypsin and chymotrypsin in the small intestine. 
  • Before the absorption in the small intestine, most proteins are already reduced to single amino acid or peptides of several amino acids. Hence, he takes several antacid tablets before eating so as to neutralize his stomach acid.
So, the correct answer is 'Decreased absorption of the protein in the steak by the small intestines'.

One of the- following is needed for the conversion of trypsinogen into trypsin  _____________.

  1. HCI

  2. Enterokinase

  3. Lipase

  4. Zymase


Correct Option: B
Explanation:

In the presence of enterokinase, inactive trypsinogen is converted into active trypsin.

So, the correct answer is 'Enterokinase'

Secretion of gastric juice is stopped by _________.

  1. Gastrin

  2. Pancreazymin

  3. Cholecystokinin

  4. Enterogastrone


Correct Option: D

Which enzyme initiates protein digestion?

  1. Pepsin

  2. Trypsin

  3. Aminopeptidase

  4. Carboxypeptidase


Correct Option: A

Rennin acts on ______________________.

  1. Milk changing casein into calcium paracaseinate at 7.2 8.2 pH

  2. Proteins in stomach

  3. Fat in intestine

  4. Milk changing casein into calcium paracaseinate at 1 3 pH


Correct Option: D

Which pair reaches the stomach totally undigested?

  1. Fat, cellulose

  2. Starch, cellulose

  3. Protein, starch

  4. Starch, fat


Correct Option: A

Which gastric secretion is correctly matched with its source

  1. Pepsin Chief cells

  2. Chymotrypsin Parietal cells

  3. HCl Goblet cells

  4. Mucus Oxyntic cells


Correct Option: A

Semi-indispensible amino acids are

  1. Arginine and histidine

  2. Methionine and threonine

  3. Leucine and isoleucine

  4. Arginine and lysine


Correct Option: A

Three major types of cells in stomach are ________________.

  1. Mucous cells, chief cells, oxyntic cells

  2. Mucous cells, chief cells, enteroendocrine cells

  3. Mucous cells, enteroendocrine cells, oxyntic cells

  4. Enteroendocrine cells, chief cells, oxyntic cells


Correct Option: A

Gastric juice contains

  1. HCl and pepsin

  2. pepsin and trypsin

  3. trypsin and HCI

  4. amylopsin and pepsin


Correct Option: A
Explanation:

Gastric juice comprising a mixture of substances, including pepsin and hydrochloric acid, secreted by glands of the stomach. Its principal function is to break down proteins into polypeptides during digestion.

Hence, the correct answer is 'HCl and pepsin'

Enzyme pepsin in the gastric juice helps in the digestion of :-

  1. carbohydrates

  2. fats

  3. nucleic acids

  4. proteins


Correct Option: D
Explanation:

Pepsin is the chief digestive enzyme in the stomach that stomach that breaks down proteins. Cells produce pepsinogen that is produced to act on mucus by epithelial cells of the stomach that helps to protect the lining of the stomach from corrosive hydrochloric acid and pepsin.

So, the correct option is 'Proteins'.

In which of the following structures protein digestion first occurs?

  1. Mouth

  2. Stomach

  3. Large intestine

  4. Small intestine


Correct Option: B
Explanation:

  • Digestion involves the mixing of food, its movement through the digestive tract, and the chemical breakdown of the large molecules of food into smaller molecules.
  •  Digestion begins in the mouth when we chew and swallow, and then it is passed on to the stomach where digestion takes place by gastric juices and enzymes secreted by the stomach and then it is passed to the small intestine where the digestion is completed. 
  • Pepsin is an enzyme which is released by zymogenic cells, the chief cells in the stomach and that degrades food proteins into peptides. Hence, the stomach is the structure where the protein digestion first occurs.
So, the correct answer is 'Stomach'.

A digestive juice with a pH of approximately 2 is found inside the

  1. mouth

  2. stomach

  3. pancreatic duct

  4. small intestine


Correct Option: B
Explanation:
  • The pH of your stomach varies, from 1-2 up to 4-5. When you eat, the stomach releases enzymes called proteases as well as hydrochloric acid to help in digestion.
  • By itself, the acid doesn't really do much for digestion, but the proteases that cleave proteins work best in an acidic environment or low pH, so after a high-protein meal, your stomach pH may drop to as low as 1 or 2. 
  • However, buffers quickly raise the pH back to 3 or 4. After the meal has been digested, your stomach pH returns to a resting level of about 4 or 5. Hence, inside of the stomach, a digestive juice with a pH of approximately 2 is found.
So, the correct answer is 'stomach'.

Choose the correct answers from the alternatives given.
Which of the following enzymes has the lowest pH optimum?

  1. Pepsin

  2. Trypsin

  3. Salivary amylase

  4. Pancreatic amylase


Correct Option: A
Explanation:
  • In humans and other mammals pepsin produced in the stomach by chief cells in an inactive form called pepsinogen. 
  •  Once the pepsinogen is released into the stomach, the low pH from the gastric acid helps in the conversion of pepsinogen into pepsin, the active enzyme.
  •  Many proteins are denatured at low pH, and most enzymes whether or not they denature require a higher pH for activity. Hence, pepsin is the enzymes has the lowest pH optimum.
So, the correct answer is 'pepsin'.

Pepsin is an enzyme which acts in

  1. acidic medium in the stomach

  2. alkaline medium in the stomach

  3. alkaline medium in the duodenum

  4. acidic medium in the duodenum


Correct Option: A
Explanation:

  • Pepsin is an enzyme which is released by zymogenic cells, the chief cells in the stomach and that degrades food proteins into peptides.
  •  It is most active in acidic environments.
  •  It exhibits maximal activity at pH 2.0 and is inactive at pH 6.5. Hence, Pepsin is an enzyme which acts in an acidic medium in the stomach.
So, the correct answer is 'acidic medium in the stomach'.

Pepsin acts in

  1. basis medium

  2. acidic medium

  3. neutral medium

  4. all types of medium.


Correct Option: B
Explanation:

Pepsin acts in 'acidic medium'.

So the correct option is B.

If pH of stomach is 1.6, then which enzyme will digest protein? 

  1. Amylase

  2. Trypsin

  3. Erypsin

  4. Pepsin


Correct Option: D
Explanation:

If the pH of the stomach is 1.6, then 'pepsin' will digest protein.

So the correct option is D.

Digestion of which component of food will be affected if the pH of stomach is made 7?

  1. Fat

  2. Protein

  3. Sucrose

  4. Vitamins


Correct Option: B
Explanation:

Digestion of 'proteins' will be affected if the pH of the stomach is made 7.

So the correct option is B.

Which of the following molecules is incorrectly paired with its source?

  1. Lysozyme-gastric juices

  2. Histamine-injured cells

  3. lnterferons-virus infected cells

  4. Immunoglobulins-plasma cells


Correct Option: A
Explanation:

Histamine is an organic nitrogenous compound involved in local immune responses, as well as regulating physiological function in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus. Histamine is involved in the inflammatory response and has a central role as a mediator of itching. 

Interferons (IFNs) are a group of signaling proteins made and released by host cells in response to the presence of several viruses. In a typical scenario, a virus-infected cell will release interferons causing nearby cells to heighten their anti-viral defenses.
Immunoglobulins, also known as antibodies, are glycoprotein molecules produced by plasma cells (white blood cells). 
Lysozyme is a special enzyme found in tears, saliva, sweat, and other body fluids. Other mucosal linings, such as the nasal cavity, also contain lysozyme. It destroys bacteria that attempt to enter our body through these passageways. In the case of tears, they protect our eyes from bacterial invaders.

So, the correct option is 'Option A'.

Partially digested semisolid food formed in stomach is ...........

  1. Chyle

  2. Chyme

  3. Bolus

  4. Chylomicron


Correct Option: B
Explanation:

Chyme is the name given to the partially digested food, formed in the stomach and enters into the small intestine(duodenum) via the pyloric valve. Chyme, also known as chymus has the consistency of oatmeal(semisolid). Chyme is a thick semisolid mass of partially digested food and digestive secretions during the digestion process. Hence, partially digested semisolid food in the stomach is chyme.

So, the correct answer is 'Chyme'.

Pepsin digests .............. .

  1. Proteins in stomach

  2. Carbohydrates in duodenum

  3. Proteins in duodenum

  4. Carbohydrates in stomach


Correct Option: A
Explanation:

Pepsin is produced in the stomach and is one of the main digestive enzymes in the digestive systems of humans and many other animals, where it helps digest the proteins in food. Zymogenic cell or peptic cell is a cell in the stomach that releases pepsinogen and chymosin.

The proenzyme pepsinogen(inactive), on exposure to hydrochloric acid, gets converted to the active enzyme pepsin. Pepsin hydrolyses proteins to polypeptide chains and initiates protein digestion in the digestion process in humans. Hence, the pepsin digests protein in the stomach.

So, the correct option is 'proteins in the stomach'.

 

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