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Allergy - class-XII

Description: allergy
Number of Questions: 46
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Tags: immune system biology animal physiology cell biology and biotechnology allergy zoology
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Which one of the following, diseases is due to an allergic reaction?

  1. Enteric fever

  2. Hay fever

  3. Skin cancer

  4. Goitre


Correct Option: B
Explanation:

Hay fever or allergic rhinitis is the allergic response caused by the hypersensitivity of dust, mites, animal fur or hairs. It is characterized by the running nose, sneezing and watery, itchy eyes. Whereas enteric fever is caused by the bacteria, Skin cancer is caused by harmful radiation i.e., UV rays and Goiter is the metabolic disorder. Thus, the correct answer is option B.

Shock organ of allergy is?

  1. Spleen

  2. Heart

  3. Lungs

  4. Kidney


Correct Option: A

The primary treatment of anaphylaxis is the application of

  1. Epinephrine injection.

  2. Glucagon injection.

  3. Insulin injection.

  4. Both B and C.


Correct Option: A
Explanation:

A- Anaphylaxis is a rapid, severe and generalized allergic reaction which may lead to death. Prompt administration of epinephrine injection can be life-saving. Timely administration of epinephrine injection decreases hospitalizations and mortality. 

Anaphylactic shock is caused due to the release of which of the following hormone?

  1. Adrenalin

  2. Histamine

  3. Glucagon

  4. Somatostatin


Correct Option: B
Explanation:

Histamines are the inflammatory substances which are released by the mast cells and basophils during the allergic reactions. The excessive release of histamine may result in anaphylactic shock. Anaphylaxis is a type of severe allergic reaction which can result in the death of the person. Antihistamines are used for the treatment and cure of the allergic reactions.

Thus, the correct answer is option B. 

Which of the following is required for the cure of anaphylactic shock?

  1. Adrenalin

  2. Antihistamine

  3. Monoclonal antibodies

  4. None of the above


Correct Option: B
Explanation:

Anaphylaxis is a type of severe allergic reaction which can result in the death of the person. The first or the primary treatment which is provided, is that the person is injected with epinephrine which reduces the basic symptoms. Antihistamines are used for the treatment and cure of the allergic reactions. The antihistamines are molecules which are similar in structure to histamine and block the H1 receptors which prevent the release and action of histamines. 

Thus, the correct answer is option B. 

The immunoglobulin involved in the type II hypersensitivity reactions is

  1. IgA.

  2. IgM.

  3. IgG.

  4. Both B and C.


Correct Option: D

Patch test can be related to 

  1. Hypersensitivity I.

  2. Hypersensitivity II.

  3. Hypersensitivity III.

  4. Hypersensitivity IV.


Correct Option: D

Cytotoxic type II reactions are also known as

  1. Hypersensitivity IV.

  2. Hypersensitivity III.

  3. Hypersensitivity II.

  4. Hypersensitivity I.


Correct Option: C

The major type of delayed type hypersensitivity is (are)

  1. Arthus Reaction.

  2. Tuberculin.

  3. Contact dermatitis.

  4. Both B and C.


Correct Option: D

IgE antibodies are known as cytotropic antibodies because

  1. They are fixed on mast cell and basophils.

  2. They are fixed on eosinophils.

  3. They are fixed on neutrophils.

  4. None of the above.


Correct Option: A

Arrange the given statement in the correct order according to type II hypersensitivity reactions.
a) IgG or IgM antibodies react with the antigen on the surface of cells.
b) Opsonization and phagocytosis. 
c) Activation of the complement cascade.
d) Cell death and lysis.

  1. a,b,c,d

  2. a,c,b,d

  3. a,d,c,b

  4. None of the above


Correct Option: B

Tuberculin, a type of hypersensitivity IV was given by ____________

  1. Louis Pasteur.

  2. Alexender Flemming.

  3. Robert Koch.

  4. None of the above.


Correct Option: C

Which of the following cell releases a hydrolytic enzyme during type IV hypersensitivity reaction?

  1. Macrophages

  2. T killer cells

  3. T helper cells

  4. All of the above


Correct Option: A
Explanation:
Type IV hypersensitivity Is a type of cell-mediated response. CD4+ helper T cells recognize antigen in a complex with major histocompatibility complex  Class II. The antigen-presenting cells are macrophages that secrete IL-12, which stimulates the proliferation of further CD4+ Th cells which secrete IL-2 and interferon gamma. This further inducing the release of other Th cytokines, thus mediating the immune response. Activated CD8+ T cells kill target cells on contact, whereas activated macrophages produce hydrolytic enzymes. Thus the correct answer is option A. 

Which of the following step is not a part of hypersensitivity type IV reaction?

  1. Sensitization

  2. Antigen presentation

  3. Phagocytosis

  4. All of the above


Correct Option: D

Hypersensitivity type IV reaction does not involve 

  1. Phagocytosis.

  2. Antibodies.

  3. Lymphokines.

  4. None of the above.


Correct Option: B

Which of the following is released by T cell to activate lymphocytes and phagocytic cells?

  1. Cytokines

  2. Antibodies

  3. Histamine

  4. None of the above


Correct Option: A
Explanation:

The T helper cells also known as CD$ _4^+$ release cytokines and trigger the activity of other immune cells.

So, the correct answer is 'Cytokines'

Which of the following cell first move to the site in type Iv hypersensitivity reaction?

  1. T helper

  2. T killer cell

  3. Monocytes

  4. None of the above


Correct Option: A

The skin prick test generally test the allergy by 

  1. Skin response

  2. Inflammatory reaction

  3. Composition of blood

  4. None of these


Correct Option: B

Which one is allergic disease?

  1. Bronchitis

  2. Bronchial asthma

  3. Emphysema

  4. Pneumonia


Correct Option: B

The skin prick test is used to diagnose

  1. Allergy

  2. Skin response

  3. Skin texture

  4. None of these


Correct Option: A

Which of the following statement can be related to anaphylaxis?

  1. It is also known as a systemic allergic response.

  2. It affects the whole body.

  3. It causes abdominal pain, nausea and vomiting.

  4. All of the above


Correct Option: D

Anaphylactic shock is 

  1. Mild local reaction to an allergen

  2. Severe local reaction

  3. Mild general reaction to an allergen

  4. Severe reaction of the whole body


Correct Option: D
Explanation:

Anaphylaxis, also known as anaphylactic shock is a serious allergic reaction that is rapid in onset and may cause death. It typically causes an itchy rash, throat or tongue swelling, shortness of breath, vomiting, lightheadedness, and low blood pressure. Common causes include insect bites and stings, foods, and medications.  The mechanism involves the release of mediators from certain types of white blood cells triggered by either immunologic or non-immunologic mechanisms.

So, the correct answer is 'Severe reaction of the whole body'.

The chemicals which can subdue the inflammatory reaction in the skin prick test is

  1. Histamine

  2. Melanin

  3. Haemoglobin

  4. None of the above


Correct Option: A
Explanation:

Histamine causes a skin response. If you dont react to histamine, your allergy skin test may not reveal the allergy.

The blood test for the allergy is used to detect 

  1. Cross reactivity

  2. Disease development

  3. Concentration of antibodies in the blood

  4. All of the above


Correct Option: D

Hay fever is due to

  1. Insect transmitted pollen

  2. Water borne pollen and pathogens

  3. Wind borne pollen

  4. Virus infected pollen


Correct Option: C

Hypersensitivity to an allergen is due to 

  1. Increase in temperature

  2. Food habits

  3. Age

  4. Aberrent functioning of immune system


Correct Option: D
Explanation:

Hypersensitivity refers to undesirable reactions produced by the immune system including allergies and autoimmunity. They are usually referred to as an abnormal (aberrant) functioning of the immune system and these reactions may be damaging, uncomfortable, or occasionally fatal. Hence, hypersensitivity to an allergen is due to the aberrant functioning of the immune system.

So, the correct answer is 'Aberrant functioning of the immune system'.

_______ is a kind of allergy. 

  1. Asthma

  2. Yellow eyes

  3. Mumps

  4. Typohoid


Correct Option: A
Explanation:

Asthma is a chronic inflammation of respiratory tracts due to accumulation of immune cells to destroy dust particles or allergens. Yellow eyes occur in jaundice patient. Jaundice is hepatic disease. Mumps is a contagious disease caused by a virus that primarily effects salivary gland. Typhoid is a bacterial infection caused by Salmonella typhi. So, the correct answer is 'Asthma'.

Histamines or inflammation producing substance are formed by

  1. Macrophages

  2. Sustentacular cells

  3. Mast cells

  4. Collagen fibres


Correct Option: C
Explanation:

A mast cell is a type of white blood cell that contains many granules rich in histamine and heparin. Specifically, it is a type of granulocyte derived from the myeloid stem cell that is a part of the immune and neuroimmune systems. Mast cells are primarily known for their role in allergy and anaphylaxis (shock). Mast cells play a key role in the inflammatory process. When activated, a mast cell can either selectively release mediators or compounds that induce inflammation, from storage granules into the local site.

So, the correct answer is 'Mast cells'.

A person stunt with bee is administrated penicillin.The person dies.Death may be due to

  1. Anaphylactic shock

  2. Prophylactic shock

  3. Autoimmunity

  4. Sedation


Correct Option: A
Explanation:

  • Anaphylaxis or anaphylactic shock is a serious allergic reaction that is rapid in onset and may cause death. It causes an itchy rash, throat or tongue swelling, shortness of breath, vomiting, lightheadedness, and low blood pressure. These symptoms are seen within minutes to hours. Common causes include insect bites and stings, foods, and medications. The primary treatment of anaphylaxis is epinephrine injection into a muscle, intravenous fluids, and positioning the person flat.
  • A person stung with the bee is administered penicillin. The person died because insect stings and medication (penicillin) are the major causes of anaphylactic shock and death.
So, the correct answer is 'Anaphylactic shock'.

A disease due to allergic reaction is 

  1. Goitre

  2. Hay fever

  3. Enteric fever

  4. Skin fever


Correct Option: B
Explanation:

Allergic rhinitis, also known as hay fever is a type of inflammation in the nose which occurs when the immune system hypersensitizes to allergens in the air. Symptoms include a runny or stuffy nose, sneezing, red, itchy, and watery eyes, and swelling around the eyes. Allergic rhinitis is typically triggered by environmental allergens such as pollen, pet hair, dust.

So, the correct answer is 'Hay fever'.

One of the inflammatory reaction induced by histamine is 

  1. Vasoconstriction of blood vessels

  2. Vasodilation of peripheral blood vessels

  3. Decreased vascular permeability

  4. Accelerated blood clotting


Correct Option: B
Explanation:

Histamine is an organic nitrogenous compound involved in the inflammatory response and has a central role as a mediator of itching. Histamine causes vasodilation of peripheral blood vessels due to which there is increased blood flow to the site of inflammation. It mediates the inflammatory reaction by the release of other chemical mediators of inflammation and causes redness, swelling etc at the site of inflammation.

So, the correct answer is 'Vasodilation of peripheral blood vessels'.

Localised inflammatory response at the sight of infection producing redness, swelling, pain and heat is due to 

  1. Histamine and cerumen

  2. Prostaglandins and histamine

  3. Cerumen and prostaglandins

  4. Cerumen and mucus


Correct Option: B
Explanation:

In localized infection, redness and heat are due to increased blood flow at body core temperature to the inflamed site, swelling is caused by accumulation of fluid, pain is due to the release of chemicals such as prostaglandin and histamine that stimulate nerve endings.Histamine are mono-amine produced from mast cells and basophils these are stored in preformed granules, and is released to a number of stimuli these lead to arterial dilation and increased venous permeability. Prostaglandins are eicosaniod produced from mast cells they leads to vasodilation, fever and pain. Hence, localized inflammatory response at the sight of infection producing redness, swelling, pain and heat is due to prostaglandin and histamine.

So, the correct answer is 'Prostaglandin and histamine'.

During inflammation,which of the following is secreted by connective tissue?

  1. Serotonin

  2. Heparin

  3. Glucagon

  4. Histamine


Correct Option: D
Explanation:

Histamine is an organic nitrogenous compound involved in the inflammatory response and has a central role as a mediator of itching. Histamine is produced by basophils and by mast cells found in nearby connective tissues. Histamine is stored in cytoplasmic granules along with other amines and rapidly released upon triggering with a variety of stimuli. It causes the contraction of smooth muscle, dilation of blood vessels etc..

So, the correct answer is 'Histamine'.

Complexes formed during immune complex mediated hypersensitivity are removed by

  1. Eosinophils and T-cells

  2. Monocytes and B-cells

  3. Eosinophills and monocytes

  4. Eosinophills and basophils


Correct Option: C

Inflammation reaction is brought about by 

  1. Mast cells

  2. Macrophages

  3. Plasma cells

  4. Adipose cells


Correct Option: A
Explanation:

A mast cell is a type of white blood cell that contains many granules rich in histamine and heparin. Mast cells play an important protective role in inflammatory and allergic reactions. When mast cells are activated, they release mediators or compounds that induce inflammation from storage granules into the local site and promotes the inflammatory response. In allergic reactions, mast cells remain inactive until an allergen binds to IgE already coated upon the cell.

So, the correct answer is 'Mast cells'.

In anaphylactic shock, the substance which causes the dilation of blood vessels and capillary leakage is 

  1. Adrenaline

  2. Benadryl

  3. Albumin

  4. Histamine


Correct Option: D
Explanation:
  • Anaphylaxis is a severe, whole-body allergic reaction. After initial exposure to a substance such as a wasp sting toxin, the allergic child's immune system becomes sensitized to that allergen. 
  • On subsequent exposure to the specific allergen, an allergic reaction, which can involve a number of different areas of the body occur. Specifically, an immunoglobulin antibody protein, IgE, is produced in response to the presence of the allergen. IgE binds to the mast cells, causing them to suddenly release a number of chemicals, including histamine, heparin, serotonin, and bradykinin. 
  • Shock can occur when the released histamine causes the blood vessels to dilate, which lowers blood pressure; histamine also causes fluids to leak from the bloodstream. Hence, In anaphylactic shock, the substance which causes the dilation of blood vessels and capillary leakage is Histamine.
 So, the correct answer is 'Histamine'.

Which of the following is caused by allergy?

  1. Leprosy

  2. Typhpid

  3. Asthma

  4. Tetanus


Correct Option: C
Explanation:
  • Asthma is a common long-term inflammatory disease of the airways of the lungs.
  • Symptoms include reversible airflow obstruction and easily triggered bronchospasms. 
  • Symptoms include episodes of wheezing, coughing, chest tightness, and shortness of breath. 
  • Asthma can be caused by Environmental factors including allergens, air pollution, and other environmental chemicals.
  •  Hence, Asthma is caused by an allergy.
  • So, the correct answer is 'Asthma'.

Anaphylactic shock is characterized 

  1. Constriction of peripherial blood vessels

  2. Drastic increase in blood pressure

  3. High permeability of capillaries causing loss of fluid from the blood

  4. All of the above


Correct Option: C
Explanation:
  • Shock is a life-threatening situation due to poor tissue perfusion with impaired cellular metabolism, manifested inturns by serious physiological abnormalities.
  • Anaphylactic shock is also called as Type I immunogenic reaction.
  • Anaphylactic shock is characterized High permeability of capillaries causing loss of fluid from the blood.
  • Anaphylaxis symptoms usually occur within minutes of exposure to an allergen. 
  • The most common anaphylactic reactions are to foods, insect stings, medications and latex.
  • So, the correct answer is 'High permeability of capillaries causing loss of fluid from the blood'

Alzheimer disease in humans is associated with the deficiency of :

  1. Gamma aminobutyric acid (GABA)

  2. Dopamine

  3. Glutamic acid

  4. Acetylcholine


Correct Option: D

The symptoms of an allergic reaction develop in response to 

  1. Interferons

  2. Interleukins

  3. Histamine

  4. Complement


Correct Option: C
Explanation:

Allergies, also known as allergic diseases are caused by hypersensitivity of the immune system to typically harmless substances in the environment. The mechanism involves immunoglobulin E antibodies (IgE) binds to an allergen and then to a receptor on mast cells or basophils where it triggers the release of inflammatory chemicals such as histamine. The release of histamine develops symptoms such as red eyes, an itchy rash, sneezing, a runny nose, shortness of breath, or swelling.

So, the correct answer is 'Histamine'.

Hay fever is caused by

  1. Hepatitis

  2. Dengue

  3. Allergy

  4. Helper T-cells


Correct Option: C
Explanation:

Hay fever (allergic rhinitis) is caused by grass pollen mostly but it can also be caused by tree pollen or weed pollen. Pollen is a fine powder enriched in protein released by plants as part of their reproductive cycle which can cause irritation in nose, eyes and throat. Symptoms of hay fever include sneezing, runny nose, itchy eyes etc. It is more common in spring and early fall. Hepatitis and dengue are viral diseases. Helper T-cells are immunity providing cells in the body

So, the correct answer is 'Allergy'

Choose the correct answers from the alternatives given.
Which of the following phyla contains members that are notorious for causing serious diseases in humans?

  1. Cnidarians

  2. Segmented worms

  3. Flatworms

  4. Chordates


Correct Option: C
Explanation:

Flatworms are generally parasitic in nature and feed on the host organism's nutrition often causing disorders as a consequence. When it comes to parasitic infection, flatworms and roundworms are likely culprits. These two types of parasitic worms can be found in a variety of habitats. They aren't always visible to the naked eye. Tapeworms and flukes cause diseases in humans and their livestock, whilst monogeneans can cause serious losses of stocks in fish farms. Schistosomiasis, also known as snail fever, is the second most devastating parasitic disease in tropical countries, behind malaria.

So, the correct option is, 'Flatworms'.

Increased asthmatic attacks in certain seasons are related to 

  1. Eating fruits preserved in tin containers

  2. Inhalation of seasonal pollen

  3. Low temperature

  4. Hot and humid environment


Correct Option: B
Explanation:

Pollens are present in air. Excess of pollen are produced in certain seasons which causes allergic reactions in several human beings. The common allergic reactions are asthma, bronchitis and rhinitis.

The term "anaphylaxis" was coined by

  1. Robert brown.

  2. Charles Richet.

  3. Bence Jones.

  4. All of the above.


Correct Option: B

Hay fever and asthma are

  1. Deficiency diseases

  2. Genetic diseases

  3. Organic diseases

  4. Allergy diseases


Correct Option: D
Explanation:

Hay fever and asthma are the allergic reactions of the body to allergens. Allergy is the hypersensitivity of a person to some foreign substance coming in contact with the body. 

Hay fever is an allergic disease where there is swollen red eyes and running nose. The pollen grains are considered as allergens.
Asthma is the condition where the tissue surrounding the respiratory tube in the lungs swell up and compressors the tube and there is the difficulty in breathing.
Hence, the correct answer is 'Allergy diseases'

Choose the correct answers from the alternatives given.
Which of the following combinations of phyla and characteristics is incorrect?

  1. Nematodaround worms, pseudocoelomate

  2. Cnidariaradial symmetry, polyp and medusa body forms

  3. Platyhelminthesflatworms, gastrovascular cavity, acoelomate

  4. Poriferagastrovascular cavity, mouth from blastopore


Correct Option: D
Explanation:

The nematodes or roundworms constitute the phylum Nematoda and have a pseudocoelom and complete digestive system. The partial, fluid-filled cavity inside the body of some invertebrates. Cnidarians have two different body plans. Both body plans have radial symmetry. A polyp, such as a hydra, sea anemone, or coral, is shaped something like a vase. Platyhelminthes, a group of soft-bodied, usually much flattened invertebrates and have cavity only one opening to the outside which, in most cnidarians, is surrounded by tentacles for capturing prey. But Porifera does not have a gastrovascular cavity as it does not have specialized tissues and phyla with a true coelom and digestive system. The protostomes include the phyla Mollusca, Annelida, and Arthropoda but not porifera. 

So, the correct option is, 'Porifera gastrovascular cavity, mouth from blastopore'.

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