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Regulation of respiration - class-XII

Description: regulation of respiration
Number of Questions: 26
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Tags: zoology cell membrane respiration biology option d: human physiology bio-chemistry
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Forced deep breathing for a few minutes by a person sitting at rest may be
followed by a temporary cessation of breathing. This is due to

  1. Too much $O _2$ in the blood

  2. Too much $CO _2$ in the blood

  3. Very little $CO _2$ in the blood

  4. Both too much $O _2$ and very little $CO _2$ in the blood


Correct Option: D
Explanation:

Deep breathing rises the $O _2$ level of the blood. By excess formation of oxyhaemoglobin the acidity of blood increases. To control it, more of free $CO _2$ changes into bicarbonates and the free $CO _2$ level in the blood decreases. So due to lack of stimulant for inspiratory centre cessation of breathing takes place, after some time $O _2$ is consumed by the tissues and rise in $CO _2$ stimulates breathing again. So, the correct answer is 'Both too much O$ _2$ and very little CO$ _2$ in the blood'.

When carbon dioxide concentration in blood increases, breathing becomes ............ and ...........

  1. Shallower and slow

  2. Slow and deep

  3. Faster and deeper

  4. None of the above


Correct Option: C
Explanation:

When the concentration of carbon dioxide increases in blood that results in decreasing the affinity of hemoglobin towards oxygen or amount of oxygen is less in blood. To compensate the oxygen amount breathing goes faster and deeper and is known as hyperventilation which is controlled by the medullary respiratory center.

So the correct option is 'Faster and deeper'.

Pneumotaxis and inhibitory centers are associated with _______________.

  1. breathing

  2. respiration

  3. digestion

  4. sleeping


Correct Option: A
Explanation:

  • Regulation of Respiration is done by the nervous mechanism.
  • A specialised centre present in the medulla region of the brain called the respiratory rhythm centre is primarily responsible for this regulation.
  • Another centre is present in the Pons region in the brain called pneumotaxis centre can moderate the function of Respiratory Rhythm Centre.
Hence, the correct answer is 'Breathing'

Respiratory rhythm centre is present:-

  1. Cerebrum

  2. Cerebellum

  3. Medulla

  4. Pons


Correct Option: C,D
Explanation:
  • The respiratory center is located in the medulla oblongata and pons, in the brainstem.
  • The respiratory center is made up of three major respiratory groups of neurons, two in the medulla and one in the pons. It is responsible for generating and maintaining the rhythm of respiration.
  • Hence Respiratory rhythm center is present Medulla and pons.
  • So, the correct answer is 'Medulla and Pons.

Pneumotaxic centre present in ____ and responsible for _______ :

  1. Limbic system , voluntary movement

  2. Hypothalamus, peristalsis

  3. Medulla oblongata , respiratory centre

  4. Pons varolii , respiratory rhythm centre


Correct Option: A

The respiratory centre of the brain is located in 

  1. Medulla oblongata

  2. Pons

  3. Cerebellum

  4. Cerebrum


Correct Option: A,B
Explanation:

Respiratory centres generate rhythmic pattern of breathing and are present in brain stem. The medullary respiratory centres constitute the primary respiratory centre and include two aggregates of neuronal cell bodies namely dorsal respiratory group and ventral respiratory group. They serve to provide output to respiratory muscles. Pontine respiratory centres are present in higher in brain stem in pons and are namely pneumotaxic centre and apneustic centre. Pontine respiratory centres modify the output from medullary centres.

Cerebellum serves to coordinate the voluntary movements of skeletal muscles as well as posture, balance and equilibrium. Cerebrum is the largest and uppermost division of brain.
It is the centre for higher thought processes required for learning, memory, language and speech. 
Therefore, the correct answer is option A and B.

A condition of over breathing is called as

  1. Hyperventilation

  2. Hypoventilation

  3. Hypoxia

  4. None of the above


Correct Option: A
Explanation:
Hyperventilation is a process of quick and deep breathing in which there is more exhalation than inhalation. This leads to reduced concentration of carbon dioxide dissolved in the blood also called hypocapnia.
So, the correct answer is 'Hyperventilation'.

Which of the following is the peripheral chemoreceptor?

  1. Aoritic body

  2. Carotid body

  3. Both A and B

  4. Spinal nerve


Correct Option: C
Explanation:
Peripheral chemoreceptors are made up of aortic and carotid bodies. Aortic body control the changes in blood oxygen and carbon dioxide. But carotid body detects changes in pH along with O$ _2$ and CO$ _2$.
So the correct answer is 'Both A and B'.

Steps of respiration are controlled by

  1. Substrates

  2. Enzymes

  3. Hormone

  4. Bile juice


Correct Option: B
Explanation:

  •  Cellular respiration is the process by which cells convert glucose into carbon dioxide and water. 
  • Cellular respiration takes place in three steps: glycolysis, the citric acid cycle and oxidative phosphorylation.
  • The main role of enzymes during the respiration reaction is to assist in transferring electrons from one molecule to another. e.g. In glycolysis, the enzyme dehydrogenase is used. Hence, the steps of respiration are controlled by enzymes.
So, the correct answer is  'enzymes'.

Breathing is controlled by

  1. Lungs

  2. Trachea

  3. Medulla oblongata

  4. Hypothalamus


Correct Option: C
Explanation:

The medulla oblongata is the lower half of the brainstem, which is continuous with the spinal cord, the upper half being the pons. The medulla contains the cardiac, respiratory, vomiting and vasomotor centres and therefore deals with the autonomic (involuntary) functions of breathing, heart rate, and blood pressure.

Pneumotaxic centre occurs in.

  1. Cerebellum

  2. Cerebrum

  3. Medulla oblongata

  4. Pons varolii


Correct Option: D

The pneumotoxic and respiratory rhythm centres are respectively present in.

  1. Pons and medulla oblongata

  2. Corpus callosum and pons

  3. Medulla oblongata and hypothalamus

  4. Diencephalon and pons


Correct Option: A

Each $100$ml of human arterial blood carries 'P' ml of $O _2$ and 'Q' ml of $CO _2$ whereas each $100$ml of venous blood carries 'R' ml of $O _2$ and 'S' ml of $CO _2$. Choose the correct values of P, Q, R and S.

  1. P-$48$ml, Q-$19$ to $20$ml, R-$52$ml, S-$14$ to $15$ml

  2. P-$19$ to $20$ml, Q-$48$ml, R-$14$ to $15$ml, S-$52$ml

  3. P-$14$ to $15$ml, Q-$52$ml, R-$19$ml to $20$ml, S-$48$ml

  4. P-$52$ml, Q-$14$ to $15$ml, R-$48$ml, S-$19$ to $20$ml


Correct Option: B

What is $pO _2$ and $pCO _2$ in synthematic arteries?

  1. $pO _2$ $40$mm Hg, $pCO _2$ $45$mm Hg

  2. $pO _2$ $95$mm Hg, $pCO _2$ $104$mm Hg

  3. $pO _2$ $95$mm Hg, $pCO _2$ $40$mm Hg

  4. $pO _2$ $45$mm Hg, $pCO _2$ $40$mm Hg

  5. $pO _2$ $104$mm Hg, $pCO _2$ $159$mm Hg


Correct Option: C

Assertion :

Inspiration occurs due to muscular relaxation.



Reason : During

inspiration, ihe diaphragm and external iniercostal muscle contract

simultaneously






  1. If both the assertion and the reason are true and the reason is a correct explanation of the assertion

  2. If both the assertion and reason are true but the reason is not a correct explanation of the assertion

  3. If the assertion is true but the reason is false

  4. If both the assertion and reason are false

  5. If the assertion is false but reason is true


Correct Option: E
Explanation:

(e) Inspiration is the result of muscular contraction. The diaphragm and external intercostal muscle contracts simultaneously. The lateral thoracic wall moves outward and upward.





In response to $CO {2}$ and $H^{+}$ concentration, the chemosensitive area and, receptors associated with aortic arch and carotic artery, send necessary signals for remedial action to ______________.

  1. Pneumotaxic centre

  2. Apneustic centre

  3. Respiratory rhythm centre

  4. Both A and B


Correct Option: A

Listed below are four respiratory capacities (i-iv) and four jumbled respiratory volumes of a normal human adult.

Respiratory volumes and capacities Volume of air
(i)    Residual volume  2500 mL
(ii)   Vital capacity   3500 mL
(iii) Inspiratory reserve volume 1200 mL
 (iv) Inspiratory capacity  4500 mL

Which one of the following is the correct matching of two capacities and volumes?

  1. (ii) 2500 mL, (iii) 4500 mL

  2. (iii) 1200 mL, (iv) 2500 mL

  3. (iv)3500mL, (i) 1200 mL

  4. (i) 4500 mL; (ii) 3500 mL


Correct Option: C
Explanation:

Respiratory volumes and capacities Volume of air

Residual volume 1200 mL Vital capacity 4500 mL
Inspiratory reserve volume 2500 mL Inspiratory capacity 3500 mL.

Rate of breathing is controlled mainly by ________________.

  1. $CO _{2}$ level in blood

  2. pH in blood

  3. $O _{2}$ level in blood

  4. $O _{2}$ level and pH in blood.


Correct Option: A
Explanation:

Rate of breathing is mainly controlled by $CO _2$ level in the blood. Excess $CO _2$ decrease the pH of the blood and it mainly stimulate the respiratory centre of the brain (i.e., Medulla oblongata) and increase the inspiratory and expiratory signals to the respiratory muscles.

Rate of breathing is controlled mainly by

  1. $CO _2$ level in blood

  2. pH in blood

  3. $O _2$ level in blood

  4. $O _2$ level and pH in blood


Correct Option: A
Explanation:

The rate of breathing is controlled mainly by CO$ _2$ level in blood. The partial pressure of carbon dioxide (PCO$ _2$) controls the respiratory rate. The respiratory centre measures the levels of carbon dioxide, oxygen and acidosis in the arterial blood and sends message accordingly. If the carbon dioxide levels in the blood increases, the rate and depth of breathing increases.

Thus, the correct answer is 'CO$ _2$ level in blood.'

Which of the following is not a stimulus for breathing?

  1. Rising $CO _2$ levels

  2. Rising blood pressure

  3. Arterial $pO _2$ below $60$mm of Hg

  4. Change in pH of arterial blood


Correct Option: A
Explanation:

An increased concentration of carbon dioxide is the strongest stimulus to breathe more deeply and more frequently. When the carbon dioxide concentration in the blood is low, the brain decreases the frequency and depth of breath.

So the correct answer is 'Rising CO2 levels'.

Types of chemoreceptors involved in respiration regulation is

  1. Central chemoreceptors

  2. Peripheral chemoreceptors

  3. Spinal chemoreceptors

  4. Both A and B


Correct Option: D
Explanation:
Central and peripheral chemoreceptors involve in the regulation of respiration. They detect reduction and elevation in the concentration level of oxygen, carbon dioxide and pH in the body.
So the correct answer is 'Both A and B'.

In response to a decrease in blood pH, the respiratory center sends nervous impulses to

  1. Increase breathing rate

  2. Decrease breathing rate

  3. Increase heart beat

  4. None of th above


Correct Option: A
Explanation:
Respiratory centre is located in the medulla oblongata and pons. They control the rate and depth of respiratory movements of the diaphragm. The increase in CO$ _2$ level in the blood lowers the pH of the blood which in response cause respiratory center to send impulses to breath fast and increase breathing rate.
So the correct answer is 'Increase breathing rate'.

Central chemoreceptors are found in

  1. Pons

  2. Medulla

  3. Spinal cord

  4. Cerebrum


Correct Option: B
Explanation:
Central chemoreceptors are located on the ventrolateral medullary surface in the central nervous system. There receptors act to detect the changes in pH of their environment by detecting alteration in the concentration of O$ _2$ and CO$ _2$ of nearby cerebrospinal fluid. The decrease in CO$ _2$ causes the blood to become more acidic while it's increase makes the blood alkaline
So, the correct answer is 'Medulla'.

Central chemoreceptors are sensitive to the

  1. pH of their environment

  2. Level of oxygen

  3. High blood pressure

  4. Level of sugar in blood


Correct Option: A
Explanation:
Central chemoreceptors are located on the ventrolateral medullary surface in the central nervous system. There receptors act to detect the changes in pH of their environment by detecting alteration in the concentration of O$ _2$ and CO$ _2$ of nearby cerebrospinal fluid. The decrease in CO$ _2$ causes the blood to become more acidic while it's increase makes the blood alkaline.
So, the correct answer is 'pH of their environment'.

In a $PCR$, which of the following components is not required?

  1. Nucleotide precursors

  2. A primer containing $3'-OH'$

  3. DNA helicase to separate the strands

  4. DNA polymerase to catalyse the reaction


Correct Option: A
Explanation:

A common laboratory technique used to make many copies (millions or billions) of a particular region of DNA is called Polymerase Chain Reaction(PCR). It requires a primer, DNA helicases, DNA polymerases, etc.,

So, the correct option is ‘ Nucleotide precursors’.

Receptors associated with aortic arch and carotid artery can recognise changes in (i) and (ii) concentration and send necessary signals to (iii) for remedial actions.

  1. (i) $O _{2}$ (ii) $CO _{2}$ (iii)pneumotaxic centre

  2. (i) $CO _{2}$ (ii) $H^+$ (iii) rhythm centre

  3. (i) $CO _{2}$ (ii) $H^+$ (iii) apneustic centre

  4. (i) $O _{2}$ (ii) $H^+$ (iii)pneumotaxic centre


Correct Option: B
Explanation:

Receptors associated with aortic arch and carotid artery can recognise a change in $CO _{2}$ and $H^+$ concentration and send necessary signals to the rhythm centre (medulla oblongata) that controls the rate of breathing.

So, the correct answer is (B).

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