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Allergy and autoimmune diseases - class-XII

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Which of the following causes almost unbearable irritation of the skin?
  1. Lint of Gossypium

  2. Staminal hair of Tradescantia

  3. Prickles of Rosa indica

  4. Stinging hair of Urtica dioca


Correct Option: D
Explanation:

The trichomes of Utrica cover the leaf and the stem surfaces, each trichome has a base attached to the epithelial layer, and a cell filled with irritant/allergent at the tip, that breaks on mechanical damage, touch, or when attempted to be eaten by herbivores. On breaking the chemical substances are injected into the predator causing unbearable irritation.

So, the correct answer is 'Stinging hair of Urtica dioca'

Which of the following stimulation results in increased gastric secretions?

  1. Mast cells

  2. H$ _1$ histamine receptor

  3. H $ _2$ histamine receptor

  4. Both A and C


Correct Option: C

Which of the following is a dangerous allergic reaction?

  1. Asphyxia

  2. Anaphylaxis

  3. Asthma

  4. None of the above


Correct Option: B

Which of the following cells secrete histamine?

  1. Plasma cell

  2. Mast cells

  3. Monocytes

  4. NK-cells


Correct Option: B
Explanation:

Mast cells are the type of white blood cells. They play important role in allergy and inflammatory reactions. They release chemicals like histamine upon exposure to the allergic component.

A noninfectious unnatural and unusual reaction to a substance or condition is 

  1. Immunity

  2. Allergy

  3. Infection

  4. Toxin


Correct Option: B
Explanation:

Allergies, also known as allergic diseases are a number of conditions caused by hypersensitivity of the immune system to typically harmless substances (non-infectious) in the environment.  Symptoms may include red eyes, an itchy rash, sneezing, a runny nose, shortness of breath, or swelling. Hence, Allergy is a noninfectious, unnatural and unusual reaction to a substance or condition.

So, the correct answer is 'Allergy'.

Excessive and inappropriate immune response to an antigen is 

  1. Anaphylaxis

  2. Multiple Sclerosis

  3. Allergy

  4. Immune deficiency


Correct Option: C
Explanation:

Allergies, also known as allergic diseases are a number of conditions caused by hypersensitivity (excessive) of the immune system to typically harmless substances in the environment. Symptoms may include red eyes, an itchy rash, sneezing, a runny nose, shortness of breath. Food, insect stings, and medications are common causes of severe reactions.

So, the correct answer is 'Allergy'.

How many sentences is/are true among the following sentences?
(a) Allergy is due to release of histamine and serotonin from mast cells.
(b) Cell mediated immunity is responsible for rejection of graft.
(c) Principles of vaccination is based on diversity of immune system.
(d) Both bone marrow and thymus provides micro environment for development and maturation of T-lymphocytes.

  1. One

  2. Two

  3. Three

  4. Four


Correct Option: A

Write true or false and correct the incorrect statement.
Allergens are the antibodies which include dust, pollen, certain foods, drugs and fur.

  1. True

  2. False


Correct Option: A

Antihistamine drugs are effective against

  1. Bacterial infection

  2. Viral infection

  3. Paraplegia

  4. Allergy


Correct Option: D
Explanation:

Antihistamines are drugs that inhibit the action of histamine in the body by blocking the receptors of histamine. When the histamine recepotrs are stimulated by histamine, it may produce allergic reactions, such as itching, hay fever and rash or hives. Antihistamines treat the symptoms of such allergic reactions.
Thus, the correct answer is option (D), 'Allergy'.

Which of the following are the symptoms of eczema, a common skin disease?

  1. Skin becomes thickened and reddish brown colour

  2. Skin drops off in the form of small scales

  3. There will be an intense itching

  4. All of the above


Correct Option: D
Explanation:
The classic symptoms of eczema are: itching - this is the worst aspect because it can make the person scratch causing further rawness of the skin and possible infections to develop; redness - caused by extra blood flowing through the blood vessels in the skin in the affected area; a grainy appearance to the skin, caused by tiny fluid filled blisters just under the skin called vesicles; weeping when the blisters burst, either by themselves or because of scratching, and the fluid oozes on to the surface of the skin; crusts or scabs that form when the fluid dries; dry, scaly skin - this may be the result of the disease or it may also be the natural skin type of the family; dry skin can be a predisposing factor to developing eczema; pale patches of skin may appear because eczema can disturb the production of pigment which controls skin colour; lichenification - a leathery, thicker skin area in response to scratching.  
Therefore, the correct answer is option B.

Which of the following is a cause of allergy which is stored in mast cells?

  1. Interferons

  2. Histamine

  3. Immunoglobulins

  4. None of the above


Correct Option: B
Explanation:

Allergies are the reactions or the response given to the antigens which are in the form of particles. Allergy is also termed as hypersensitivity. The cells release IgE antibodies, histamines and other cytokines which manifest the symptoms of the reaction. When the allergen is encountered, the mast cells and basophils undergo degranulation which releases histamine. Histamine is the inflammatory agent. 

Thus, the correct answer is option B. 

Which of the following affects H$ _1$ receptor?

  1. Agglutination

  2. Allergic manifestations

  3. Opsonization

  4. None of the above


Correct Option: B

Specific allergen immunotherapy is also known as

  1. Desensitization.

  2. Immunization.

  3. Agglutination.

  4. Both A and C.


Correct Option: A

Which of the following is a symptom of allergy?

  1. Urticaria

  2. Rhintis

  3. Asthma

  4. All of the above


Correct Option: D
Explanation:

Allergies are the reactions or the response given to the antigens which are in the form of particles. Allergy is also termed as hypersensitivity. The cells release IgE antibodies, histamines and other cytokines which manifest the symptoms of the reaction. Allergy may result in urticaria which is the development of skin rash with reddening and swelling of the regions. The allergen results in stimulation of mucus secretion and sneezing which causes rhinitis. The common example of allergy is asthma which results in the constriction of the bronchi and shortness of breath due to the blocking of the airway.  

Thus, the correct answer is option D. 

The immune system which works against self is

  1. Self immune system

  2. Autoimmunity

  3. Specific immunity

  4. None of the above


Correct Option: B
Explanation:

Autoimmunity is the system of immune responses of an organism against its own cells and tissues. It is the abnormal immune response in which immune system attacks healthy cells.
Thus, the correct answer is option B.

Which of the following is an autoimmune disease?

  1. Rheumatoid arthritis

  2. Grave's disease

  3. Hashimoto's disease

  4. All of the above


Correct Option: D
Explanation:

Autoimmune disease is a condition in which our own immune system attacks our own tissues. Rheumatoid arthritis is an autoimmune disease that causes chronic inflammation of the joints.
Grave's disease is an autoimmune disease in which the patient;s own immune system attacks the thyroid gland causing it to produce too much of thyroid hormone.
Hashimoto's disease is an autoimmune condition caused by inflammation of the thyroid gland.
Thus, the correct answer is option D.

.............. is a kind of allergy

  1. Asthma

  2. Yellow eyes

  3. Typhoid

  4. Mumps


Correct Option: A
Explanation:

An allergy is a hypersensitivity disorder of the immune system. Symptoms include red eyes, itchiness, and runny nose, eczema, hives, or an asthma attack. Out of the given options, only asthma is an allergy. Asthma and allergies often go hand-in-hand. Asthma is a disease of the branches of the windpipe (bronchial tubes), which carry air in and out of the lungs. There are several different types of asthma. Allergic asthma is a type of asthma that is triggered by an allergy (for example, pollen or mold spores).

Use of antihistamines and steroid give a quick relief from

  1. Nausea

  2. Headache

  3. Allergy

  4. Cough


Correct Option: C
Explanation:
  • Antihistamines are drugs which are used to treat allergic rhinitis and other allergies. Antihistamines can give relief when a person has nasal congestion, sneezing, or hives because of pollen, dust mites, or animal allergy. Histamine is mostly responsible for allergic reactions. Antihistamines block the action of histamines.
  • A steroid is a biologically active organic compound. Steroids such as corticosteroids are used in the treatment of allergic reactions by reducing inflammation associated with allergies. They prevent and treat nasal stuffiness, sneezing, and itchy, runny nose due to seasonal or year-round allergies. They can also decrease inflammation and swelling from other types of allergic reactions
  • So, the correct answer is 'Allergy'.

In higher vertebrates the immune system can distinguish self cells from nonself ones.If this property is lost due to genetic abnormality and it attacks self cells , it leads to

  1. Active immunity

  2. Allergic response

  3. Graft rejection

  4. Auto immune disease


Correct Option: D
Explanation:

An autoimmune disease is a condition arising from an abnormal immune response to normal body tissue. In an autoimmune disease, the immune system fails to recognize self-cells and produces antibodies against self-cells. Common symptoms include low-grade fever and feeling tired. Autoimmune disease is due to genetic abnormality or other environmental factors. 

So, the correct answer is 'Autoimmune disease'.

Use of anti-histamines and steroids give a quick relief from -

  1. Headache

  2. Allergy

  3. Nausea

  4. Cough


Correct Option: B

Choose the correct answer from the alternatives given.
Hay fever is a sign of

  1. Malnutrition

  2. Allergy

  3. Old age

  4. Over work


Correct Option: B

Hypersensitivity towards any foreign material or particle is known as :

  1. Hypergenital disease

  2. Congenital disease

  3. cancer

  4. Allergy


Correct Option: D
Explanation:

The undesirable responses or reaction to any foreign particles produced by the immune system is known as hypersensitivity. These reactions will result into allergic reaction and auto immunity.

The type of immunity that develops as a result of natural exposure to an antigen in the environment is

  1. Natural innate immunity

  2. Naturally acquired passive immunity

  3. Nonspecific immunity

  4. Naturally acquired active immunity


Correct Option: A
Explanation:

Innate immunity works without concern about how much damage happened but to protect the body and the body exposed to an antigen in an environment develops natural innate immunity.

So the correct option is 'Natural innate immunity.'

When body starts rejecting its own cells, it is called as

  1. Immuno deficiency

  2. Immunosuppression

  3. Autografting

  4. Autoimmunity


Correct Option: D
Explanation:

Autoimmune diseases are disorders in which the bodys immune system attacks the body's own cells and organs with proteins called autoantibodies; this process is called autoimmunity. The bodys immune system normally makes large numbers of proteins called antibodies to help the body fight off infections. In some cases, however, the body makes autoantibodies. Examples include systemic lupus erythematosus (SLE), Sjgren's syndrome, Hashimoto's thyroiditis, Graves' disease, idiopathic thrombocytopenic purpura, Addison's Disease, rheumatoid arthritis (RA), polymyositis (PM).

Therefore, the correct answer is option D.

Which of the following term is used as inherited tendency to develop allergic diseases?

  1. Atopy

  2. Epitope

  3. Virulence

  4. None of the above


Correct Option: A
Explanation:

Atopy is the condition which has been developed due to exposure to allergens in which the person is susceptible to allergic reactions. This is an inherited syndrome. The person is more likely to develop the allergic reactions like rash, rhinitis, asthma, etc when encountered with the allergen. 

Thus, the correct answer is option A. 

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