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Organic Chemistry Test

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Cytokinesis is the process of splitting the daughter cells apart.The protein participating in cell division and cytokinesis is

  1. Nectins

  2. Desmogleins

  3. T-cadherin

  4. Actin


Correct Option: D
Explanation:

Actin participates in many important cellular processes including muscle contraction, cell motility, cell division and cytokinesis, vesicle and organelle movement, cell signaling, and the establishment and maintenance of cell junctions and cell shape.

The protein molecule, permanently attached to the biological membrane, is

  1. transmembrane protein

  2. peripheral membrane proteins

  3. integral membrane protein

  4. membrane glycoproteins


Correct Option: C
Explanation:

An integral membrane protein (IMP) is a protein molecule that is permanently attached to the biological membrane. Proteins that cross the membrane are surrounded by annular lipids, which are defined as lipids that are in direct contact with a membrane protein.

Which of the following lipids is a 18-carbon amino alcohol?

  1. Sphingosine

  2. Cerebrosides

  3. Ceramides

  4. Sphingomyelin


Correct Option: A
Explanation:

Sphingosine is an 18-carbon amino alcohol with an unsaturated hydrocarbon chain, which forms a primary part of sphingolipids, a class of cell membrane lipids that include sphingomyelin, an important phospholipid.

Which of the following drugs slows bone loss in the body?

  1. Abilify

  2. Accutane

  3. Actiq

  4. Actonel


Correct Option: D
Explanation:

Actonel is in a group of medicines called bisphosphonates. Risedronate alters the cycle of bone formation and breakdown in the body. Actonel slows bone loss while increasing bone mass, which may prevent bone fractures.

The lipids which play significant role in signal transmission and cell recognition are

  1. phospholipids

  2. lipoprotein

  3. sphingolipids

  4. sterols


Correct Option: C
Explanation:

Sphingolipids are a class of lipids derived from the aliphatic amino alcohol sphingosine. These compounds play an important role in signal transmission and cell recognition.

The lipoprotein enabling the movement of fats and cholesterol, within the water-based solution of the bloodstream, is

  1. very-low-density lipoprotein

  2. intermediate-density lipoprotein

  3. low-density lipoprotein

  4. high-density lipoprotein


Correct Option: B
Explanation:

Intermediate-density lipoprotein belongs to the lipoprotein particle family and is formed from the degradation of very low-density lipoproteins. IDL is one of the five major groups of lipoproteins (chylomicrons, VLDL, IDL, LDL and HDL) that enable fats and cholesterol to move within the water-based solution of the bloodstream.

Which of the following lipids is a biological precursor to vitamin D2?

  1. Cholesterol

  2. Phytosterols

  3. Ergosterol

  4. Hopanoids


Correct Option: C
Explanation:

Ergosterol is a biological precursor (a provitamin) to vitamin D2. It is turned into viosterol by ultraviolet light, and is then converted into ergocalciferol, which is a form of vitamin D.

Which of the following enzymes cleaves amyloid precursor protein in its transmembrane region?

  1. Alpha secretases

  2. Amino acid permeases

  3. Carnitine-acylcarnitine translocases

  4. Ornithine translocase


Correct Option: A
Explanation:

Alpha secretases are a family of proteolytic enzymes that cleave amyloid precursor protein (APP) in its transmembrane region. Specifically, alpha secretases cleave within the fragment that gives rise to the Alzheimer's disease-associated peptide amyloid beta when APP is instead processed by beta secretase and gamma secretase.

Among the following, ___________ is an appetite suppressant.

  1. adderall

  2. adipex-P

  3. advair

  4. allegra


Correct Option: B
Explanation:

Adipex-P (phentermine) is a stimulant that is similar to an amphetamine. Adipex-P is an appetite suppressant that affects the central nervous system.

Male impotence is treated by

  1. byetta

  2. celexa

  3. chantix

  4. cialis


Correct Option: D
Explanation:

Cialis relaxes muscles and increases blood flow to particular areas of the body. Cialis is used to treat erectile dysfunction (impotence) in men.

The chloride channel activators lead to the opening of membrane chloride channels. Among the following, ____________ is a chloride channel activator.

  1. Ambien

  2. Amitiza

  3. Aricept

  4. Avandia


Correct Option: B
Explanation:

Amitiza is a chloride channel activator. It increases fluid secretion in the intestines which increases intestinal muscle movement and helps make it easier to pass stools (bowel movements). Amitiza is used to treat chronic constipation in adults.

The dyes used to stain cartilage in bone specimens is

  1. alizarin

  2. red 2G

  3. bismarck brown Y

  4. congo red


Correct Option: C
Explanation:

Bismarck brown Y is a diazo dye. It is used in histology for staining tissues. It stains acid mucins to yellow colour. It can be used with live cells. It is also used to stain cartilage in bone specimens.

The dye used to stain mitochondria is

  1. crystal violet

  2. fuchsine

  3. janus Green B

  4. yellow 2G


Correct Option: C
Explanation:

Janus Green B is a basic dye and vital stain used in histology. It is also used to stain mitochondria supravitally.

Serum is the clear liquid, separated from clotted blood. Which of the following proteins is found in serum?

  1. Fibronectin

  2. Vitronectin

  3. Collagen

  4. Laminins


Correct Option: B
Explanation:

Vitronectin is an abundant glycoprotein found in serum and the extracellular matrix

The erythrocytes are also called red blood cells.The dye used to stain erythrocytes is

  1. martius yellow

  2. methyl orange

  3. methyl red

  4. naphthol green B


Correct Option: A
Explanation:

Martius yellow is  a dye. It has been used to stain erythrocytes yellow, so they contrast well with red fibrin, in trichrome methods such as Lendrum's Picro Mallory and Slidder's Martius, Scarlet and Blue (MSB).

Which of the following mediates attachment between a cell and the tissues surrounding it?

  1. Selectins

  2. Neural Cell Adhesion Molecule

  3. Cadherins

  4. Integrins


Correct Option: D
Explanation:

Integrins are receptors that mediate attachment between a cell and the tissues surrounding it, which may be other cells or the ECM. They also play a role in cell signaling and thereby regulate cellular shape, motility, and the cell cycle.

Ovulation is the release of a mature egg ( ovum) from the ovarian follicle.Which of the following stimulates ovulation in females?

  1. Ciprofloxacin

  2. Claritin

  3. Clomid

  4. Cymbalta


Correct Option: C
Explanation:

Clomid stimulates the release of hormones necessary for ovulation to occur. It is mainly used for treating female infertility.

A lysochrome is a soluble dye used for biochemical staining. Among the following, ____________ is a chloride

  1. orange G

  2. rose Bengal

  3. sudan II

  4. titan yellow


Correct Option: C
Explanation:

Sudan II is a lysochrome (fat-soluble dye) azo dye used for staining of triglycerides in frozen sections, and some protein bound lipids and lipoproteins on paraffin sections.

The first, commercially used, successful synthetic polymer was

  1. bakelite

  2. neoprene

  3. nylon

  4. polyvinyl chloride


Correct Option: C
Explanation:

Nylon is a thermoplastic silky material, first used commercially in a nylon-bristled toothbrush. It is made of repeating units linked by amide bonds and is frequently referred to as polyamide (PA). Nylon was the first commercially successful synthetic polymer.

Oligodendrocytes is a type of brain cell. Which of the following lipids is synthesized in the oligodendrocytes in the CNS?

  1. Phosphocholine

  2. Ganglioside

  3. Globoside

  4. Sulfatides


Correct Option: D
Explanation:

Sulfatides are a class of sulfated galactosylceramides synthesized primarily in the oligodendrocytes in the central nervous system. Sulfatides are a type of sulfolipid.

Which of the following is an acyclic sesquiterpene alcohol ?

  1. Farnesol

  2. Dolichol

  3. Asparagine

  4. Cytosol


Correct Option: A
Explanation:

Farnesol is a natural organic compound which is an acyclic sesquiterpene alcohol found as a colourless liquid. It is insoluble in water, but miscible with oils. It is the building block of most, and possibly all, acyclic sesquiterpenoids and is an important starting compound for organic synthesis.

The dyes used in biomedical imaging belong to

  1. chrysoine resorcinol

  2. xylene cyanol

  3. cyanine

  4. SYBR Green I


Correct Option: C
Explanation:

Cyanine is a non-systematic name of a synthetic dye family belonging to polymethine group. Cyanines have many uses as fluorescent dyes, particularly in biomedical imaging. Depending on the structure, they cover the spectrum from IR to UV.

The polymer used in making missiles, solid propellant, rocket motors etc. is

  1. polystyrene

  2. polyethylene

  3. polypropylene

  4. polyacrylonitrile


Correct Option: D
Explanation:

Polyacrylonitrile (PAN) is a resinous, fibrous, or rubbery organic polymer. Almost all polyacrylonitrile resins are copolymers made from mixtures of monomers with acrylonitrile as the main component. It is chemically modified to make the carbon fibers found in plenty of both high-tech and common daily applications such as civil and military aircraft primary and secondary structures, missiles, solid propellant, rocket motors, pressure vessels, fishing rods, tennis rackets, badminton rackets and high-tech bicycles.

The drug belonging to angiotensin II receptor antagonists group is

  1. dilaudid

  2. diovan

  3. effexor

  4. enbrel


Correct Option: B
Explanation:

Diovan is in a group of drugs called angiotensin II receptor antagonists. It keeps blood vessels away from narrowing, which lowers blood pressure and improves blood flow.

Cholesterol is carried to body tissues by

  1. apolipoprotein B

  2. apolipoprotein E

  3. cholesteryl ester

  4. a triglyceride


Correct Option: A
Explanation:

Apolipoprotein B is the primary apolipoprotein of low-density lipoproteins which is responsible for carrying cholesterol to tissues.

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