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Enzymes

Description: Mutation Class XI / XIIEnzymes
Number of Questions: 15
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Tags: Mutation Class XI / XII Enzymes
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Which of the following biomolecules constitute enzymes?

  1. Carbohydrates

  2. Fats

  3. Proteins

  4. Nucleic acids

  5. Inorganic compounds

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Correct Option: C
Explanation:

 
 

What is an apoenzyme?

  1. Enzyme + prosthetic group

  2. Enzymes having the same function, but a different molecular configuration are called holoenzymes

  3. Inactive form of enzymes

  4. The protein part of an enzyme

  5. Non-protein part of an enzyme

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Correct Option: D
Explanation:

The protein part of an enzyme is called apoenzyme, to which the coenzyme attaches to form an active enzyme.

 
 

What is the Michaelis-Menten's equation used for?

  1. To study the enzyme kinetics

  2. To determine the quantity of product formed per gram of the enzyme

  3. To study the nature of an enzyme

  4. To determine the optimum temperature required to carry out a reaction

  5. To determine the structure of the enzyme

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Correct Option: A
Explanation:

 
 

What does Michaelis Menten constant Km signifies?

  1. Concentration of substrate

  2. Affinity of an enzyme for its substrate

  3. Both (1) and (2)

  4. It is the t1/2 of the reaction.

  5. The rate at which ES complex dissociates to form the product.

Show answer
Correct Option: C
Explanation:

 
 

According to which theory does the enzyme molecule undergo changes at active site on contact with a substrate?

  1. Fischer's lock and key model

  2. Koshland's induced fit model

  3. Michaelis Menten hypothesis

  4. Lineweaver- Burk equation

  5. Autocatalysis

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Correct Option: B
Explanation:

According to this theory, the enzyme molecule undergoes configurational or geometric changes in the active site on contact with the substrate.

 
 

Which are the main assumptions of Michaelis Menten hypothesis?

  1. A single substrate and a single product are involved.

  2. An intermediate enzyme-substrate complex is formed.

  3. The rate of decomposition of the substrate is proportional to the concentration of enzyme-substrate complex.

  4. All 1, 2 and 3

  5. One enzyme can lead to the formation of many products.

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Correct Option: D
Explanation:

 
 

According to which theory does a substrate fit in the enzyme like a key fits in a lock to yield a enzyme-substrate complex?

  1. Koshland's induced fit model

  2. Michaelis Menten hypothesis

  3. Fischer's lock and key model

  4. Lineweaver-Burk equation

  5. Autocatalysis

Show answer
Correct Option: C
Explanation:

According to this model, the union between the substrate and the enzyme takes place at the active site more or less in a manner in which a key fits a lock and results in the formation of enzyme-substrate complex.

 
 

What is meant by feedback inhibition?

  1. Inhibition of enzyme activity at an active site by an inhibitor which is structurally similar to a substrate

  2. Inhibition of first step of biosynthesis by the end-product of reaction

  3. Inhibition by a structurally different inhibitor at a place other than active site

  4. Denaturation of enzyme

  5. Mixed competitive and non-competitive inhibition

Show answer
Correct Option: B
Explanation:

 
 

If melonic acid inhibits succinic acid dehydrogenase which catalyses the conversion of succinic acid to fumaric acid, which type of process takes place?

  1. Feedback inhibition

  2. Competitive inhibition

  3. Non-competitive inhibition

  4. Zymogen activation

  5. Denaturation of enzyme

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Correct Option: B
Explanation:

 
 

Which of the following class of enzymes would convert glucose-6-phosphate to fructose-6-phosphate?

  1. Synthases

  2. Isomerases

  3. Oxidoreductases

  4. Hydrolases

  5. Transferases

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Correct Option: B
Explanation:

 
 

Which type of inhibition is the sensitivity of urease to various ions of heavy metals?

  1. Feedback inhibition

  2. Competitive inhibition

  3. Non-competitive inhibition

  4. Zymogen activation

  5. Denaturation

Show answer
Correct Option: C
Explanation:

Urease is highly sensitive to these metal ions and these ions non-competitively inhibit urease at some site other than the active site. Therefore, it is non-competitive inhibition.

 
 

In which of the following enzymes, is nickel used as a co-factor?

  1. Catalase

  2. Arginase

  3. Urease

  4. Nitrogenase

  5. Hydrogenase

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Correct Option: C
Explanation:

 
 

Which of the following enzymes fall under the class of hydrolases?

  1. Dehydrogenase, Oxidase

  2. Transaminase, Transphosphatase

  3. Protease, Carbohydrases

  4. Phosphohexose isomerase

  5. Pyruvate carboxylase

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Correct Option: C
Explanation:

These enzymes break down large molecules into smaller ones by the introduction of water and breaking of specific covalent bonds. They are hydrolases.

 
 

What is a complete enzyme known as?

  1. Apoenzyme

  2. Holoenzyme

  3. Pro-enzyme

  4. Isoenzyme

  5. Exoenzyme

Show answer
Correct Option: B
Explanation:

 
 

Who among the following coined the word enzyme?

  1. Edward Buchner

  2. J. B. Sumner

  3. W. Kuhne

  4. Emil Fischer

  5. D.E. Koshland

Show answer
Correct Option: C
Explanation:

 
 

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