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Human Physiology

Description: This test will help the students to revise the topic human physiology thoroughly.
Number of Questions: 100
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Tags: human physiology biology test Coordination & control in Animals Nutrition in Plants and Animals Respiration in Animals Transportation in Animals Excretion in animals & Plants Reproduction in Animals
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Which among the following statements regarding the human digestion process is INCORRECT?

  1. Digestion begins from the mouth of an organism.

  2. Gastric acid is about 0.5% hydrochloric acid.

  3. The gastric phase is stimulated by distension of the stomach.

  4. The gastric phase occurs at the sight, thought and smell of food.

  5. The human gastrointestinal tract is around 9 m long.


Correct Option: D
Explanation:

Different phases of digestion take place including the cephalic phase, gastric phase and intestinal phase. The cephalic phase occurs at the sight, thought and smell of food, which stimulate the cerebral cortex. Taste and smell stimuli are sent to the hypothalamus and medulla oblongata.

Absorption of the most of the nutrients present in the diet occurs in the small intestine. Which of the following nutrients is/are absorbed by passive diffusion in small intestine?

  1. Fructose

  2. Sodium bicarbonate

  3. Lipids

  4. Iron

  5. Vitamin B12


Correct Option: C
Explanation:

Water and lipids are absorbed by passive diffusion throughout the small intestine.

Carbohydrates are one of the main types of nutrients and the most important source of energy for our body. Which among the following statements regarding the digestion of carbohydrates in human gut is FALSE?

  1. The ileum enzymes attached to the epithelial cells complete the digestion of disaccharides to monosaccharides.

  2. Pancreatic amylase digests all the remaining starch in the oesophagus.

  3. The monsaccharides are absorbed by active transport.

  4. The plant fibres are passed through the digestive system as fibre.

  5. Salivary amylase starts the digestion of starch.


Correct Option: B
Explanation:

Pancreatic amylase digests all the remaining starch in the duodenum. Amylase digests starch molecules from the ends of the chains in two-glucose units, forming the disaccharide maltose. Glycogen is also digested here.

Which among the following can be excluded from the functions of the lungs?

  1. The lungs serve as a reservoir of blood in the body.

  2. They form defence system against air-borne infection.

  3. They filter small blood clots formed in arteries.

  4. They maintain sterility of the body.

  5. They secrete immunoglobulin A.


Correct Option: C
Explanation:

Lungs filter gas micro-bubbles occurring in the venous blood stream such as those created during decompression after underwater diving. They also filter out small blood clots formed in veins.

Which of the following is/are not found in the upper respiratory tract?

  1. Fauces

  2. Paranasal sinuses

  3. Oropharynx

  4. Nasal cavity

  5. Lungs


Correct Option: E
Explanation:

The lower respiratory tract or lower airway, consists of the trachea, bronchi (primary, secondary and tertiary), bronchioles (including terminal and respiratory) and lungs.

The eye is the organ of vision. Which among the following parts of the mammalian eye governs the total amount of light entering into the eye?

  1. Cornea

  2. Eye lens

  3. Retina

  4. Iris

  5. Blind spot


Correct Option: D
Explanation:

Just behind the cornea is a dark coloured muscular diaphragm which has a small circular opening in the middle. The iris regulates the amount of light entering the eye. It regulates the light by adjusting the size of the pupil.

Which among the following structures forms a complete ring of cartilage around the trachea in human beings?

  1. Corniculate cartilage

  2. Cricoid cartilage

  3. Thyroid cartilage

  4. Cuneiform cartilages

  5. Arytenoid cartilage


Correct Option: B
Explanation:

The cricoid cartilage is the only complete ring of cartilage around the trachea.

In human beings, the pitch and the volume are manipulated in which of the following parts of the respiratory tract?

  1. Carina

  2. Trachea

  3. Laryngopharynx

  4. Uvula

  5. Larynx


Correct Option: E
Explanation:

Sound is generated in the larynx and that is where pitch and volume are manipulated. The strength of expiration from the lungs also contributes to loudness.

In an adult human kidney, the brush border is a characteristic feature of which among the following parts of a nephron?

  1. Proximal convoluted tubule

  2. Distal convoluted tubule

  3. Ascending limb of the loop of Henle

  4. Descending limb of loop of Henle

  5. Renal corpuscles


Correct Option: A
Explanation:

The cells lining the proximal convoluted tubule are well adapted for reabsorption of materials from the filtrate. They have abundant mitochondria and bear numerous microvilli on the free side thus giving brush border appearance.

Angiotensinogen is a protein produced and secreted by which among the following cells of the kidney tubules?

  1. Hepatic cells

  2. Nephridia

  3. Macula densa cells

  4. Juxtaglomerular cells

  5. Podocytes


Correct Option: A
Explanation:

Angiotensinogen is an a-globulin protein produced by liver. Renin serves as an enzyme in the conversion of the plasma protein angiotensinogen into angiotensin. This protein stimulates the adrenal cortex to produce aldosterone which acts on the cells of the ascending limb of the loop of Henle and increases the rate of reabsorption of Na+.

A prominent groove located in the right atrium of the heart is known as

  1. papillary muscle

  2. chordae tendineae

  3. trabeculae carneae

  4. sulcus

  5. musculi pectinati


Correct Option: D
Explanation:

The terminal sulcus is a groove in the right atrium of the heart. The terminal sulcus marks the separation of the right atrial pectinate muscle from the sinus venarum. The terminal sulcus extends from the front of the superior vena cava to the front of the inferior vena cava

Ultrafiltration in the kidneys is the process by which large molecules that are essential to the body are filtered out so that they can be reabsorbed. The site of ultrafiltration in the kidney is

  1. renal sinus

  2. renal fascia

  3. renal papilla

  4. renal medulla

  5. renal cortex


Correct Option: E
Explanation:

The renal cortex is the outer portion of the kidney between the renal capsule and the renal medulla. It is the part of the kidney where ultrafiltration occurs. Erythropoietin is produced in the renal cortex.

Which among the following blood cells are produced in the bone marrow of human beings?

  1. Monocytes

  2. Lymphocytes

  3. Basophils

  4. Eosinophils

  5. Neutrophils


Correct Option: A
Explanation:

They are produced in the bone marrow. They have a large kidney-shaped nucleus. The cytoplasm is more than in lymphocytes. They number 100 to 700 per cubic mm. They function as tissue macrophages feeding on damaged tissues.

Which among the following renal cells participate(s) in acid-base homeostasis of the kidney?

  1. Intercalated cells

  2. Principal cell

  3. Podocytes

  4. Brush border cell

  5. Macula densa


Correct Option: A
Explanation:

Intercalated cells come in α and β varieties and participate in acid-base homeostasis.

Which among the following nerves innervate(s) the human penis?

  1. Sacral spinal nerve

  2. Genitofemoral nerve

  3. Sacral nerves 2, 3 and 4

  4. Sciatic nerve

  5. Labialscrotal nerve


Correct Option: C
Explanation:

Innervation of the penis comes from the pudendal nerve which is made up of the 2nd, 3rd and 4th sacral nerves. The penile nerve (also known as the dorsal nerve of the penis) is the deepest branch of the pudendal nerve.

Which among the following statements does NOT characterise kidneys?

  1. The cortex extends into the medulla as renal column of Bertin.

  2. The inner region of kidney is termed as renal medulla.

  3. The nephrons are held together by connective tissue.

  4. The position of kidneys is symmetrical.

  5. The kidneys are placed against the back wall of the abdominal cavity.


Correct Option: D
Explanation:

The kidneys are covered by the peritoneum in the front and on the side and they rest against the abdominal muscles. Their position is slightly asymmetrical, the left kidney being a little higher than the right.

Which among the following is INCORRECT regarding the blood coagulation in human beings?

  1. Platelets are the fragments of megakaryocytes.

  2. Primary haemostasis initially involves vasodilation.

  3. Platelet activation stimulates production of thromboxane.

  4. Fibrin monomers get cross-linked by factor XIIIa.

  5. Clotting is initiated by exposure of tissue factor-bearing cells to plasma clotting factors.


Correct Option: B
Explanation:

Primary haemostasis initially involves vasoconstriction in response to vascular damage which limits blood loss, and subsequent platelet adhesion to the damaged area and activation due to exposure of subendothelial matrix.

Which among the following structures is responsible for warming or cooling of inhaled air within 1 degree of body temperature?

  1. The laryngopharynx

  2. The oropharynx

  3. The larynx

  4. The nasopharynx

  5. The nasal cavity


Correct Option: E
Explanation:

The nasal cavity conditions the air to be received by the other areas of the respiratory tract. Owing to the large surface area provided by the nasal conchae, the air passing through the nasal cavity is warmed or cooled to within 1 degree of body temperature.

Which among the following statements regarding the trachea in human beings is INCORRECT?

  1. The oesophagus lies anteriorly to the trachea.

  2. A flap-like epiglottis closes the opening to the larynx during swallowing.

  3. The cricoid cartilage is the only complete ring of cartilage in the trachea.

  4. The trachea is lined with pseudostratified columnar epithelium.

  5. There are fifteen to twenty incomplete C-shaped tracheal rings of cartilage.


Correct Option: A
Explanation:

The oesophagus lies posteriorly to the trachea. Circular bands of fibrous connective tissue called the annular ligaments of trachea join the tracheal rings together.

Adam's apple is a forward protrusion of the largest cartilage of the larynx. Which among the following cartilages form(s) Adam's apple?

  1. Cricoid cartilage

  2. Thyroid cartilage

  3. Corniculate cartilages

  4. Cuneiform cartilages

  5. Arytenoid cartilages


Correct Option: B
Explanation:

This forms the Adam's apple. It is usually larger in males than in females. The thyrohyoid membrane is a ligament associated with the thyroid cartilage that connects the thyroid cartilage with the hyoid bone.

There are twelve pairs of cranial nerves in human beings. Ten of the twelve cranial nerves originate in which part of the human brain?

  1. Hypothalamus

  2. Pituitary gland

  3. Brainstem

  4. Pineal gland

  5. Thalamus


Correct Option: C
Explanation:

The brainstem includes the midbrain, pons and medulla. It acts as a relay center connecting the cerebrum and cerebellum to the spinal cord. It performs many automatic functions such as breathing, heart rate, body temperature, wake and sleep cycles, digestion, sneezing, coughing, vomiting, and swallowing. Ten of the twelve cranial nerves originate in the brainstem.

In mammals, the process of ventilation is normally controlled by the autonomic nervous system. Which among the following statements does NOT characterise ventilation in humans?

  1. Pregnancy tends to increase ventilation.

  2. The tone of respiratory muscle is modulated by muscle spindles via a reflex arc.

  3. Ventilatory rate is usually controlled and determined by blood levels of oxygen as determined by metabolic rate.

  4. During moderate exercise, ventilation increases in proportion to metabolic production of carbon dioxide.

  5. Afferent neurons from the carotid bodies and aortic bodies are via the glossopharyngeal nerve.


Correct Option: C
Explanation:

Ventilatory rate (minute volume) is strictly controlled and determined primarily by blood levels of carbon dioxide as determined by metabolic rate. Blood levels of oxygen become important in hypoxia. These levels are sensed by chemoreceptors in the medulla oblongata for pH, and the carotid and aortic bodies for oxygen and carbon dioxide.

Lung capacity is defined as the maximum air which can be held in the two lungs at any given time. Which among the following has the minimum value?

  1. Residual air

  2. Alveolar air

  3. Inspiratory reserve volume

  4. Expiratory reserve volume

  5. Vital capacity


Correct Option: B
Explanation:

Some amount of air remains in the various parts of the respiratory tract also. The air in the trachea and bronchi (where no diffusion occurs) is called dead space air (350ml). The air remaining in the alveoli or air sacs is alveolar air (150mL).

Which among the following statements does NOT characterise cellular respiration?

  1. In the mitochondria of the cells, oxygen is consumed and carbon dioxide is produced.

  2. Blood with haemoglobin is able to transport 26 times more oxygen than plasma without haemoglobin.

  3. Each body cell releases carbon dioxide into nearby capillaries by perfusion.

  4. The body cells uses ATP for all metabolic reactions.

  5. The capillaries are permeable to oxygen.


Correct Option: C
Explanation:

Each body cell releases carbon dioxide into nearby capillaries by diffusion, because the level of carbon dioxide is higher in the body cells than in the blood. In the capillaries, some of the carbon dioxide is dissolved in plasma and some is taken by the haemoglobin, but most enters the red blood cells where it binds with water to form carbonic acid.

The nucleus of which of the following leukocytes are considered as lysosomes?

  1. Monocytes

  2. Eosinophils

  3. Neutrophils

  4. Lymphocytes

  5. Basophils


Correct Option: B
Explanation:

Eosinophils have a bilobed nucleus (two lobes connected by a narrow strand of chromatin). Their granules are considered to be lysosomes. Eosinophils actively phagocytize complexes formed by the action of antibodies on antigens (foreign substances).

Vasodilators open (dilate) the blood vessels. Which among the following is a vasodilator?

  1. Antidiuretic hormone

  2. Epinephrine and norepinephrine

  3. Atrial natriuretic peptide

  4. Angiotensin II

  5. Nicotine


Correct Option: C
Explanation:

Atrial natriuretic peptide (ANP), a hormone secreted by the atria of the heart, lowers blood pressure by causing vasodilation and by stimulating the kidneys to excrete more water and Na+(lowering blood pressure by reducing blood volume).

In human adults, about 5 litres of blood contributes to 7-8% to the body weight. Which among the following statements regarding blood composition is WRONG?

  1. Erythrocytes are the dominant cells in the blood.

  2. Blood platelets perform their functions exclusively in the blood stream.

  3. Erythrocytes contribute about 43% of the total volume of the blood.

  4. Blood cells have epithelial origin.

  5. Leukocytes can leave the blood stream.


Correct Option: D
Explanation:

Blood is sometimes considered to be a fluid connective tissue because of the mesenchymal origin of its cells and a low ratio of cells to liquid intercellular substance, the blood plasma.

Which among the following statements regarding the innervation of the human heart is FALSE?

  1. Preganglionic sympathetic fibres ascend from the upper five thoracic segments of the spinal cord.

  2. The effect of autonomic nervous system on coronary artery and blood flow is reciprocatory.

  3. Postganglionic fibres descend to the heart and form two plexuses.

  4. During rest, the vagal tone is recessive.

  5. Afferent fibres carrying pain sensation run to the spinal cord.


Correct Option: D
Explanation:

During rest, the vagal tone is the dominant. There is continuous parasympathetic activity that has a negative chronotropic character.

Which among the following does not characterise a mammalian heart?

  1. A single heartbeat lasts about 0.8 seconds.

  2. The impulses are delayed for about 0.1 second at bundle of HIS.

  3. The SA node generates electrical impulses.

  4. Few cardiac cells can contract without any signal from the nervous system.

  5. The heart is effectively a syncytium.


Correct Option: B
Explanation:

The atrioventricular node, located in the wall between the right atrium and the right ventricle. Here, the impulses are delayed for about 0.1s before spreading to the walls of the ventricle.

Which among the following is made of non-keratinised stratified squamous epithelium?

  1. Specialised mucosa

  2. Labial mucosa

  3. Buccal mucosa

  4. Lining mucosa

  5. Masticatory mucosa


Correct Option: D
Explanation:

Lining mucosa is made up of nonkeratinised stratified squamous epithelium. It is found almost everywhere else in the oral cavity.

The lining wall of the alimentary canal appears different in different parts of the gut, reflecting their different roles; but always has the same basic layers. Which among the following layers prevents food from travelling backwards?

  1. The oral mucosa

  2. The serosa

  3. The submucosa

  4. The gastric mucosa

  5. The muscularis externa


Correct Option: E
Explanation:

The muscularis externa consists of an inner circular layer and a longitudinal outer muscular layer. The circular muscle layer prevents food from traveling backward and the longitudinal layer shortens the tract.

Which among the following statements regarding the heart sounds is INCORRECT?

  1. The third heart sound is pathological in children, but physiologic in adults.

  2. The third sound is a result of vibration of ventricular wall and the leaflets of the opened AV valves after rapid inflow of blood.

  3. Turbulent blood flow is a result of stenotic (narrowed) valves or blood vessels.

  4. Heart murmurs are pathological noises that results from abnormal blood flow in the heart or blood vessels.

  5. Heart sounds are a result of beating heart and resultant blood flow.


Correct Option: A
Explanation:

Third heart sound is physiologic in children but pathological in adults. The four heart sound is a result of the atrial systole and vibration of the AV valves, due to blood rush during atrial systole. It is inaudible neither in adults nor in children.

Which among the following statements regarding digestion of proteins in alimentary canal is INCORRECT?

  1. Pancreatic endopeptidases continue to digest proteins in the duodenum.

  2. Exopeptidases remove amino acids one by one from the ends of peptide chains.

  3. Protease enzymes are potentially dangerous.

  4. Rennin is normally only produced by infant mammals.

  5. Pepsin is an exopeptidase.


Correct Option: E
Explanation:

Pepsin (in gastric juice) digests proteins to peptides, 6-12 amino acids long. Pepsin is an endopeptidase, which means it hydrolyses peptide bonds in the middle of a polypeptide chain. It is unusual in that it has an optimum pH of about 2 and stops working at neutral pH.

In which part of the allimentary canal are some of the water and electrolytes removed from the food?

  1. Large intestine

  2. Small intestine

  3. Stomach

  4. Oesophagus

  5. Mouth


Correct Option: A
Explanation:

After passing through the small intestine, food passes into the large intestine. In the large intestine, some of the water and electrolytes (chemicals like sodium) are removed from the food. Many microbes (bacteria like Bacteroides, Lactobacillus acidophilus, Escherichia coli, and Klebsiella) in the large intestine help in the digestion process.

While examining primordial germ cells in a prepubertal male under a microscope, in which stage of the cell cycle will you find them?

  1. Metaphase

  2. Telophase

  3. Anaphase

  4. Prophase

  5. Interphase


Correct Option: E
Explanation:

Interphase occurs just prior to cell division. Prepubertal male primordial germ cells are reactivated from interphase at puberty and enter rounds of mitoses followed by meiosis 1 and 2 to produce unique haploid sperm.

The replacement of breast milk by other foods of low protein and calorific value causes which of the following diseases in human beings?

  1. Kwashiorkor

  2. Marasmus

  3. Goitre

  4. Xerophthalmia

  5. Rickets


Correct Option: B
Explanation:

This is due to protein deficiency and not food calories intake. In developing countries like India it is common in infants below one year of age. The causal factor may be due to early replacement of mother's milk by other foods of low protein and calorific value. This may happen if the mother has a second pregnancy when the older infant is still too young.

Digestion is a complex process and takes place in different parts of the alimentary canal. In which part of the alimentary canal are some of the water and electrolytes removed from the food?

  1. In the large intestine

  2. In the small intestine

  3. In the oesophagus

  4. In the stomach

  5. In the mouth


Correct Option: A
Explanation:

After passing through the small intestine, food passes into the large intestine. In the large intestine, some of the water and electrolytes (chemicals like sodium) are removed from the food. Many microbes (bacteria like Bacteroides, Lactobacillus acidophilus, Escherichia coli, and Klebsiella) in the large intestine help in the digestion process.

Which of the following diseases is caused by decreased intake of niacin or tryptophan in the diet?

  1. Korsakoff's syndrome

  2. Wet beriberi

  3. Pellagra

  4. Infantile beriberi

  5. Dry beriberi


Correct Option: C
Explanation:

Pellagra is a vitamin deficiency disease most frequently caused by a chronic lack of niacin (vitamin B3 in the diet. It can be caused by decreased intake of niacin or tryptophan, and possibly by excessive intake of leucine.

In human beings, the pulmonary artery originates from

  1. limbus of the fossa ovalis

  2. fossa ovalis

  3. crista terminalis

  4. conus arteriosus

  5. septomarginal trabecula


Correct Option: D
Explanation:

It is a conical extension of the right ventricle in the heart of mammals, from which the pulmonary artery originates.

Which among the following statements does NOT characterise normal menstrual cycle in females?

  1. Estrogen builds up the lining of the uterus.

  2. Progesterone secretion decreases after ovulation.

  3. A drop in progesterone causes the lining to break down.

  4. The menstrual cycle is from day 1 of bleeding to day 1 of the next time of bleeding.

  5. About once a month, the uterus grows a new lining to get ready for a fertilised egg.


Correct Option: B
Explanation:

Progesterone secretion increases after an ovary releases an egg (ovulation) at the middle of the cycle. This helps the estrogen keep the lining thick and ready for a fertilised egg.

The conduction of electrical impulses along the nerves becomes poor due to the deficiency of

  1. vitamin D

  2. vitamin C

  3. vitamin K

  4. vitamin A

  5. vitamin E


Correct Option: E
Explanation:

Vitamin E deficiency causes nerve problems due to poor conduction of electrical impulses along nerves due to changes in nerve membrane structure and function.

Kwashiorkor cases occur in areas of famine or poor food supply. Which among the following statements regarding kwashiorkor is INCORRECT?

  1. In kwashiorkor patients, protein should be supplied only for catabolic purposes.

  2. Extreme fluid retention is observed in individuals suffering from kwashiorkor.

  3. In kwashiorkor, the osmotic balance in the digestive tract gets disturbed.

  4. Children with kwashiorkor are more susceptible to diphtheria and typhoid.

  5. Kwashiorkor is a form of severe protein-energy malnutrition in children.


Correct Option: A
Explanation:

Protein should be supplied only for anabolic purposes. The catabolic needs should be satisfied with carbohydrate and fat. Protein catabolism involves the urea cycle, which is located in the liver and can easily overwhelm the capacity of an already damaged organ.

Which among the following male accessory glands is thought to be responsible for enhancing the movement of spermatozoa in all mammals?

  1. Urethral gland

  2. Prostate Gland

  3. Bulbourethral gland

  4. Vesicular gland

  5. Ampullary gland


Correct Option: B
Explanation:

The secretion of this gland is more serous in dogs and more mucous in bulls. It serves to promote the movement of spermatozoa in all the mammals and to form a vaginal plug.

Who discovered sperm cells?

  1. Herman Boerhaave

  2. Pierre Fauchard

  3. Nicolaas Hartsoeker

  4. Antonie van Leeuwenhoek

  5. William Harvey


Correct Option: D
Explanation:

Antonie Philips van Leeuwenhoek is commonly known as the Father of Microbiology.Sperm cells were first observed by him.

Which among the following parts of the brain governs blinking of eyes and sneezing in human beings?

  1. Cerebellum

  2. Cerebral aqueduct

  3. Pineal gland

  4. Corpus callosum

  5. Medulla oblongata


Correct Option: E
Explanation:

Medulla oblongata is the connection between the spinal cord and the brain. It is important for essential reflexes, e.g. breathing, heart rate and regulation of blood vessels, and other reflexes, e.g. swallowing, salivation, blinking, coughing, sneezing.

Which among the following options characterises the events taking place in the testis?

  1. Sertoli cells allow the unrestrained diffusion of water-soluble substances between seminiferous tubules and blood.

  2. Leydig cells secrete testosterone.

  3. Sertoli cells reciprocate to testosterone by synthesising androgen binding protein.

  4. Leydig cells provide nutrition to the spermatozoa.

  5. Sertoli cells line the seminiferous tubules and boost the developing sperms in males.


Correct Option: B
Explanation:

As a consequence of stimulation with luteinizing hormone the interstitial cells (Leydig) secrete testosterone into the intertubular tissue, where it is absorbed by blood vessels, lymphatics, and the seminiferous tubules.

The activation of skeletal muscles in human beings is controlled by which among the following types of nervous system?

  1. Peripheral nervous system

  2. Central nervous system

  3. Autonomic nervous system

  4. Somatic nervous system

  5. Parasympathetic nervous system


Correct Option: D
Explanation:

Somatic nervous system is a subdivision of the PNS that controls voluntary activities such as the activation of skeletal muscles.

Which among the following is/are associated with increasing the rate of transmission of nerve impulses?

  1. Synapse

  2. Schwann cells

  3. Myelin sheath

  4. Nodes of Ranvier

  5. Neurilemma


Correct Option: C
Explanation:

A complex material formed of protein and phospholipid (fat) that is laid down as a sheath around the axons of certain neurons. It iIncreases the rate of transmission of nerve impulses.

The second ventricle of the brain is also known as

  1. paracoel

  2. diacoel

  3. rhinocoel

  4. metacoel

  5. metocoel


Correct Option: A
Explanation:

Paracoel are the second ventricles.

Which of the following cranial nerves innervates the muscles of tongue in human beings?

  1. XII nerve

  2. VIII nerve

  3. IX nerve

  4. X nerve

  5. VII nerve


Correct Option: A
Explanation:

This nerve innervates the muscles of the tongue.

The deficiency of which of the following vitamins causes anemia and certain neurologic dysfunction in humans?

  1. Vitamin B2

  2. Vitamin B12

  3. Vitamin B9

  4. Vitamin B7

  5. Vitamin B6


Correct Option: B
Explanation:

Vitamin B12 deficiency can lead to vitamin B12 deficiency anemia and neurologic dysfunction. A mild deficiency may not cause any discernible symptoms, but as the deficiency becomes more significant symptoms of anemia may result.

Which among the following statements regarding sympathetic nervous system is INCORRECT?

  1. Sympathetic nerves originate inside the vertebral column.

  2. Sympathetic nervous system is responsible for up- and down-regulating in many homeostatic mechanisms of the body.

  3. Sympathetic nervous system mobilises the body in a fight-or-flight response.

  4. Sympathetic nervous system stimulation causes vasodilation of most blood vessels in the body.

  5. Sympathetic nervous system stimulates gut motility, and urinary system output and function.


Correct Option: D
Explanation:

Sympathetic nervous system stimulation causes vasoconstriction of most blood vessels, including those of the skeletal muscle.

The nervous system of mammals uses both electrical and chemical means to send and receive messages via neurons. Which of the following parts of a neuron receive(s) information?

  1. Neurilemma

  2. Axon

  3. Axon terminal

  4. Dendrites

  5. Nodes of Ranvier


Correct Option: D
Explanation:

In a neuron, the dendrite receives a signal from an axon terminal of a neuron through a synapse.

Which among the following lobes of the brain governs the emotions and memory of an individual?

  1. Temporal lobe

  2. Occipital lobe

  3. Parietal lobe

  4. Frontal lobe

  5. Limbic lobe


Correct Option: E
Explanation:

Limbic lobe of the brain governs the emotions and memory of an individual.

Which of the following types of cells are involved in the production of cerebrospinal fluid (CSF)?

  1. Purkinje cells

  2. Glial cells

  3. Pyramidal cells

  4. Oligodendroctyes

  5. Ependymal cells


Correct Option: E
Explanation:

Ependyma is the thin epithelium-like lining of the ventricular system of the brain and the central canal of the spinal cord. Ependyma is one of the four types of neuroglia in the central nervous system (CNS). It is involved in the production of cerebrospinal fluid (CSF).

In a neuron, the ion channels are located at

  1. axolemma

  2. axon terminals

  3. axon hillock

  4. axoplasm

  5. nodes of Ranvier


Correct Option: A
Explanation:

The axolemma is the cell membrane surrounding an axon. It is responsible for maintaining the membrane potential of the neuron, and it contains ion channels through which ions can flow.

Which among the following is a mixed nerve?

  1. Spinal nerve

  2. Cranial nerve

  3. Efferent nerve

  4. Motor nerve

  5. Sensory nerve


Correct Option: A
Explanation:

A spinal nerve is a mixed nerve, which carries motor, sensory, and autonomic signals between the spinal cord and the body. There are 31 pairs of spinal nerves, one on each side of the human vertebral column.

Phagocytosis is defined as the process of engulfing of microorganisms or other cells and foreign particles by phagocytes. Which of the following types of cells are phagocytic?

  1. Hepatocytes

  2. Lymphocytes

  3. Monocytes

  4. Erythrocytes

  5. Plasma cells


Correct Option: C
Explanation:

They are circulating immature macrophages or dendritic cells.

A ventricle is a muscular chamber that pumps blood out of the heart and into the circulatory system. Which among the following statements regarding the ventricles of heart is FALSE?

  1. When the right ventricle relaxes, there is more pressure in the pulmonary trunk.

  2. The left ventricle is smaller and its walls are thinner than those of the right ventricle.

  3. The chordae tendineae are attached to papillary muscles at the opposite bottom side of the right ventricle.

  4. When the left ventricle relaxes, the aortic semilunar valve gets closed.

  5. When the left ventricle contracts, the left AV valve gets closed.


Correct Option: B
Explanation:

The left ventricle is the pumping chamber for the systemic circulation. Because a greater blood pressure is required to pump blood through the much more extensive systemic circulation than through the pulmonary circulation, the left ventricle is larger and its walls are thicker than those of the right ventricle.

The heart is the pump of the human circulatory system. Which among the following does not characterise the circulation of blood by human heart?

  1. The majority of vasculature in the body constricts to norepinephrine.

  2. The papillary muscles are attached with the mitral valve.

  3. If the posterior descending artery is supplied by the circumflex artery (CX), then the coronary circulation is termed as left-dominant.

  4. During the ventricular systole, the subendocardial coronary vessels are compressed due to the high intra-artirial pressures.

  5. The heart regulates the amount of vasodilation or vasoconstriction of the coronary arteries.


Correct Option: D
Explanation:

During contraction of the ventricular myocardium (systole), the subendocardial coronary vessels (the vessels that enter the myocardium) are compressed due to the high intraventricular pressures.

Which among the following neurons is characterised by having an axon which has been split into two branches?

  1. Interneuron

  2. Multipolar neuron

  3. Pseudounipolar neuron

  4. Unipolar neuron

  5. Bipolar neuron


Correct Option: C
Explanation:

A pseudounipolar neuron is a kind of sensory neuron in the peripheral nervous system. This neuron contains an axon that has split into two branches; one branch runs to the periphery and the other to the spinal cord.

Which of the following valves guards the opening of aorta?

  1. Tricuspid valve

  2. Bicuspid valve

  3. Mitral valve

  4. Semilunar valve

  5. Pulmonary valve


Correct Option: D
Explanation:

It is a trilobed valve, present at the opening of aorta into the left ventricle.

A plasma cell is a mature lymphocyte that is specialised for antibody (immunoglobulin) production. Which among the following characteristics regarding the plasma cells is false?

  1. They have a thin layer of cytoplasm.

  2. They are derived from T-cells.

  3. They develop into B-cells.

  4. They secrete large amounts of gamma interferon.

  5. They have a highly developed rough endoplasmic reticulum.


Correct Option: E
Explanation:

Plasma cells secrete large amounts of antibody and therefore require well developed ER in order to make sufficient amounts of this protein.

In mammals, the nerves, pulmonary vessels and bronchi enter the lungs at the

  1. hilum

  2. apex

  3. mediastinum

  4. trachea

  5. base


Correct Option: A
Explanation:

The hilum of the lung is a triangular part which allows the other structures forming the root of the lung to enter and exit. It permits arteries, veins, nerves, bronchi, and other structures to enter and exit.

The mesenchyme developing just below the germinal epithelium is the origin of which analogous cell types?

  1. Ovarian tissue

  2. Sex cords

  3. Sertoli and granulosa cells

  4. Spermatogonia and oogonia

  5. Leydig and thecal cells


Correct Option: E
Explanation:

Mesenchyme arising beneath the germinal epithelium in the testes is the precursor to testicular interstitial cells, or Leydig cells, while in the ovaries it is the precursor to ovarian stroma or thecal cells.

During the follicular phase, the dominant follicle arises as a result of secretion of which of the following hormones?

  1. Matrix-degrading proteases

  2. hCG

  3. Androgen

  4. LH

  5. FSH


Correct Option: E
Explanation:

Follicle-stimulating hormone (FSH) causes maturation of a cohort of early-stage ovarian follicles; one of these will ultimately become the dominant, or Graafian follicle.

MIS stands for Mullerian Inhibiting Substance, which is a gonadal hormone with multiple functions. It is secreted by which among the following parts of the male reproductive system?

  1. Cells of Cowper's glands

  2. Cells of the seminal vesicles

  3. Cells of the sertoli cells

  4. Cells of the leydig cells

  5. Cells of prostate gland


Correct Option: C
Explanation:

A Sertoli cell is a 'nurse' cell of the testes. The MIS glycoprotein is produced by Sertoli cells of the testes during fetal and neo-natal life in males.

Which among the following can be excluded from the function of Sertoli cells?

  1. Aromatisation of androgen precursors to estrogen

  2. Maintenance of the blood-testis barrier

  3. Maintenance of the position of primordial germ cells against the basement membrane

  4. Synthesis of inhibin andantimullerian hormone

  5. Metabolic support of developing spermatozoa


Correct Option: C
Explanation:

Primordial germ cells are maintained against the basement membrane of the seminiferous tubules; Sertoli cells do not appear to have a role in this process.

The vas deferens is important for which important function of spermatogenesis in males?

  1. Sperm nourishment

  2. Sperm storage

  3. Maintenance of blood-testis barrier

  4. Testosterone production 

  5. Sperm transit


Correct Option: D
Explanation:

Testosterone is a main male sex hormone. It is produced by the male testes and influences men physically, emotionally and sexually.

The Müllerian ducts (or paramesonephric ducts) are paired ducts of mesodermal origin in the embryo. Which among the following structures originate(s) from the Mullerian ducts?

  1. Upper two-thirds of the vagina

  2. Uterus

  3. Ovaries

  4. Urinary bladder

  5. Urogenital sinus


Correct Option: B
Explanation:

Once the Mullerian ducts have reached the urogenital sinus and the vaginal plate has formed the ducts will begin to fuse centrally. This forms the body of the uterus.

Which of the following is unlikely to be a consequence of testicular growth in males?

  1. Decreased in the production of Müllerian inhibiting substance

  2. Occurence of spermatogenesis in many structures of the male reproductive system

  3. Leydig cell stimulation

  4. Initiation of spermatogenesis  

  5. Increased mass of seminiferous tubules


Correct Option: A
Explanation:

Mullerian inhibiting substance (MIS) is responsible for causing the mullerian ducts to degenerate, accounting for the sole development of male internal genitalia in a fetus with a functional testis. If it is absent during fetal development, female internal genitalia would develop by default

Which among the following provide(s) blood supply to the penis?

  1. Genitofemoral artery

  2. Internal pudendal arteries

  3. Pampiniform plexus

  4. Femoral artery

  5. Greater palatine artery


Correct Option: B
Explanation:

The internal pudendal arteries serve as the penile blood supply by entering the penis dorsally and running deep into the tissues of the corpora cavernosa. The internal pudendal artery becomes the penile artery.

The right testicular vein gets emptied into which vascular structure?

  1. Superior vena cava

  2. Right renal artery

  3. Pampiniform plexus

  4. Left renal vein

  5. Inferior vena cava


Correct Option: E
Explanation:

The right testicular vein drains into the inferior vena cava at an acute angle.

Which among the following structures of male reproductive system enters the prostate gland to empty into the urethra?

  1. Seminal vesicle

  2. Ampulla

  3. Ejaculatory duct

  4. Epididymis

  5. Ductus deferens


Correct Option: C
Explanation:

The ejaculatory duct in males is formed by a union of the ampulla of the ductus deferens and the duct of the seminal vesicle. This duct receives secretions from the seminal vesicle and prostate gland and penetrates the prostate gland where it empties into the urethra.

In which of the following processes do the abductor muscles compress the lungs?

  1. Perfusion

  2. Diffusion

  3. Convection

  4. Inspiration

  5. Expiration


Correct Option: E
Explanation:

During the act of expiration the diaphragm potentially relaxes and the elastic recoil of the lungs, chest wall, and abductor muscles compress the lungs.

Which among the following structures neutralise(s) the acidity being present due to the drops of urine in the urethra?

  1. Seminal vesicles

  2. Bulbourethral glands

  3. Prostate gland

  4. Urethra

  5. Ejaculatory ducts


Correct Option: B
Explanation:

These are pea-sized structures located on the sides of the urethra. These glands produces transparent, slippery fluid which serves to lubricate the urethra and to neutralize the acidity being present due to the drops of urine in the urethra.

Which among the following is/are NOT a part of internal reproductive system of the females?

  1. Ovaries

  2. Uterus

  3. Vagina

  4. Fallopian tubes

  5. Bartholin's glands


Correct Option: E
Explanation:

These glands are located beside the vaginal opening and produce a fluid secretion. It is a one of the important parts among the main external structures of the female reproductive system.

The first milk produced by a woman in the first few days after delivery is known as

  1. bolus

  2. fabulinus

  3. colostrum

  4. urochrome

  5. meconium


Correct Option: C
Explanation:

Colostrum is a form of milk produced by the mammary glands in late pregnancy and the few days after delivery in all the mammals. Human colostrum is thick, sticky and yellowish.

Which among the following structures in mammals (including humans) connects the limbic system to other parts of the brain?

  1. The epithalamus

  2. The metathalamus

  3. The hypothalamus

  4. The subthalamus

  5. The thalamus


Correct Option: A
Explanation:

The epithalamus is a dorsal part of the diencephalon and connects the limbic system to other parts of the brain.

Which among the following structures is/are NOT associated with human heart?

  1. Intervenous tubercle

  2. Sulcus terminalis

  3. Chordae tendineae

  4. Trabeculae carneae

  5. Musculi pectinati


Correct Option: B
Explanation:

It is a V shaped groove diffentiating the anterior two thirds of the tongue from the posterior third and containing the circumvallate papillae.

Which among the following parts of brain provides remarkable distinctions between humans and other animals?

  1. The spinal cord

  2. The thalamus

  3. The cerebellum

  4. The limbic system

  5. The cerebral cortex


Correct Option: E
Explanation:

The cerebral cortex is the portion of the brain that provides remarkable distinctions between humans and other animals. It enables humans not only to receive and interpret all kinds of sensory information, such as color, odor, taste, and sound, but also to remember, analyze, interpret, make decisions, and perform a host of other higher brain functions.

In human beings, the pulmonary artery originates from which of the following structures?

  1. Conus arteriosus

  2. Fossa ovalis

  3. Limbus of the fossa ovalis

  4. Crista terminalis

  5. Septomarginal trabecula


Correct Option: A
Explanation:

It is a conical extension of the right ventricle in the heart of mammals, from which the pulmonary artery originates.

Which among the following structures accomodates the circumvallate papillae?

  1. Intervenous tubercle

  2. Chordae tendineae

  3. Trabeculae carneae

  4. Sulcus terminalis

  5. Musculi pectinati


Correct Option: D
Explanation:

It is a V shaped groove diffentiating the anterior two thirds of the tongue from the posterior third and containing the circumvallate papillae.

The oxygenated haemolymph entering the heart is isolated by which of the following surfaces of the heart?

  1. Serous pericardium

  2. Sternocostal surface

  3. Fibrous pericardium

  4. Pericardial sinus

  5. Coronary sulcus


Correct Option: D
Explanation:

It refers to the wall at the back of the pericardial sac. It acts as a collection reservoir to isolate oxygenated haemolymph entering the heart.

The human sperm is equipped with proteolytic enzymes capable to digest the zona pellucida. These enzymes are located at

  1. cumulus

  2. acrosome

  3. corona

  4. head

  5. foreskin


Correct Option: B
Explanation:

The acrosome is the part of the sperm containing proteolytic enzymes to digest the zona pellucida. It is exposed by the process of capacitation. Then, under the influence of substances released by corona radiata cells, it releases its proteolytic enzymes and penetrates the oocyte.

Avascular structures are characterised by the lack of blood vessels. Which one of the following parts of the human eye is normally avascular?

  1. Cornea

  2. Pinna

  3. Retina

  4. Conjunctiva

  5. Iris


Correct Option: E
Explanation:

The iris is a highly vascularised organ which needs to contract and relax.

Aditi met with an accident. Doctor told her husband that in the accident, the cranial nerve innervating the lateral rectus muscles of the eye has been damaged. Which among the following muscles must the doctor be referring to?

  1. Vagus nerve

  2. Glossopharyngeal nerve

  3. Abducens nerve

  4. Hypoglossal nerve

  5. Accessory nerve


Correct Option: C
Explanation:

The abducens innervates the lateral rectus muscles of the eye.

Which among the following structures associated with human eyes is a small pink coloured globular nodule present at the inner corner of both the eyes?

  1. Lacrimal lake

  2. Lacrimal canaliculi

  3. Lacrimal sac

  4. Nasolacrimal duct

  5. Caruncula lacrimalis


Correct Option: E
Explanation:

The caruncula lacrimalis is the small, pink, globular nodule at the inner corner (the medial angle) of the eye. It is made of skin covering sebaceous (oil) and sudoriferous (sweat) glands.

The blood vessels which nourish the retina of the human eyes are located in

  1. ciliary body

  2. Bruch's membrane

  3. aqueous humor

  4. anterior chamber

  5. choroid


Correct Option: E
Explanation:

Choroid is layer of the eye behind the retina, contains blood vessels that nourish the retina.

The enzymes being secreted in the human stomach are called gastric enzymes. Which among the following is secreted by the stomach to destroy the bacteria and viruses?

  1. Gastric lipase

  2. Gastrin

  3. Mucin

  4. Intrinsic factor

  5. Pepsin


Correct Option: C
Explanation:

The stomach has a priority to destroy the bacteria and viruses using its highly acidic environment but also has a duty to protect its own lining from its acid. The way that the stomach achieves this is by secreting mucin and bicarbonate via its mucous cells, and also by having a rapid cell turn-over.

Which among the following statements regarding the functions of pancreas is INCORRECT?

  1. Progenitor cells of the pancreas differentiate to form two lines of committed endocrine precursor cells.

  2. The control of exocrine function of pancreas is done through hormones.

  3. The pancreas is also the main source of enzymes for polysaccharides.

  4. The pancreas secretes lysophospholipase and cholesterol esterase.

  5. Pancreatic secretions from ductal cells contain bicarbonate ions.


Correct Option: C
Explanation:

The pancreas is also the main source of enzymes for digesting fats (lipids) and proteins. The enzymes that digest polysaccharides, by contrast, are primarily produced by the walls of the intestines.

The glycosylase released by the tips of the villi of epithelium in small intestine in humans is

  1. amylase

  2. lactase

  3. β-galactosidase

  4. chitinase

  5. sucrase


Correct Option: A
Explanation:

Amylases are used in breadmaking and to break down complex sugars, such as starch (found in flour), into simple sugars. Yeast then feeds on these simple sugars and converts it into the waste products of alcohol and CO2. This imparts flavour and causes the bread to rise.

Which among the following enzymes is produced in the duodenum and is known as a significant brush border enzyme?

  1. Secretin

  2. Cholecystokinin

  3. Gastric inhibitory peptide

  4. Motilin

  5. Lactase


Correct Option: E
Explanation:

This is a significant brush border enzyme.This enzyme decreases with age, and as such lactose intolerance is often a common abdominal complaint in the older population, manifesting with bloating, abdominal pain, and osmotic diarrhea.

In which part of the intestine of mammals are M cells found?  

  1. In the dome area of Peyer's patches

  2. In the pyloric antrum

  3. In the follicles of the Peyer's patches

  4. In the lamina propria

  5. Interacting with intraionthelial lymphocytes


Correct Option: A
Explanation:

Peyer's patches are covered by specialized epithelium (follicle-associated epithelium). Some of these epithelial cells have surfaces, which seem folded under the scanning electron microscope. These microfold, or M, cells sample and actively transport particulate antigens from the lumen into the dome area, where priming of both T and B lymphocytes occurs.

Nephron is the basic structural and functional unit of the kidney. Which among the following does not constitute a part of nephron?

  1. Distal convoluted tubule

  2. Collecting duct

  3. Loop of Henle

  4. Proximal convoluted tubule

  5. Bowman's capsule


Correct Option: B
Explanation:

A uriniferous tubule/nephron is a long tubule differentiated into four regions: Bowman's capsule, proximal convoluted tubule, loop of Henle and distal convoluted tubule. Collecting ducts are the larger tubes, each receiving the collecting tubules of several nephrons. Collecting duct does not form a part of the uriniferous tubule.

Which among the following do(es) not constitute the excretory system of a man?

  1. Urethra

  2. Urinary bladder

  3. Gall bladder

  4. Ureters

  5. Kidney


Correct Option: C
Explanation:

The excretory system in man is formed of one pair of kidneys, a pair of ureters, a urinary bladder and a urethra. The gall bladder is a pear-shaped, hollow structure located under the liver and on the right side of the abdomen.

The adenoids are present in which part of the respiratory tract?

  1. Nasopharynx

  2. Primary bronchus

  3. Respiratory bronchiole

  4. Terminal bronchiole

  5. Alveolus


Correct Option: A
Explanation:

It extends from the base of the skull to the upper surface of the soft palate. It includes the space between the internal nares and the soft palate, and lies above the oral cavity. The adenoids are lymphoid tissue structures located in the posterior wall of the nasopharynx.

The mode of excretion as observed in land reptiles, insects and some land crustaceans is

  1. aminotelism

  2. ureaplasma

  3. ureotelism

  4. uricotelism

  5. ammonotelism


Correct Option: D
Explanation:

Elimination of uric acid as the main nitrogenous waste material is called uricotelism. Animals showing uricotelism are called uricotelic animals. It is a common method seen in birds, land reptiles, insects, land snails and some land crustaceans.

Which among the following organs of human body is regarded as the graveyard of the red blood cells?

  1. Spleen

  2. Diaphragm

  3. Oesophagus

  4. Pharynx

  5. Epiglottis


Correct Option: A
Explanation:

The spleen breaks down both red and white blood cells that are spent. This is why, it is sometimes known as the 'graveyard of red blood cells'. A product of this digestion is the pigment bilirubin which is sent to the liver and secreted in the bile.

Which of the following is/are the pace setter(s) of the human heart?

  1. Atrioventricular bundle

  2. Papillary muscles

  3. Purkinje fibres

  4. SA node

  5. AV node


Correct Option: D
Explanation:

The sinoatrial (SA) node is a section of nodal tissue that is located in the upper wall of the right atrium. The SA node is also referred to as the pacemaker of the heart.

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