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Microorganisms and Diseases (GATE - XL)

Description: proteins
Number of Questions: 15
Created by:
Tags: carrier transmission Emerging Infectious Diseases Nonspecific Defense of Host Reservoirs of Infection Human Diseases Caused by Viruses
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Which of the following organisms are distinguished by GeneXpert testing system?

  1. Acid fast from non-acid fast organisms

  2. NTM broad category microbes

  3. NTM from mycobacterium tuberculosis

  4. Mycobacterium tuberculosis from Nocardia


Correct Option: C
Explanation:

GeneXpert testing system distinguishes fairly well between NTMs and mycobacterium tuberculosis. NTMs (non-tuberculous mycobacteria) are emerging microbes that cause a spectrum of diseases including TB-like lung disease, localised infections of the lymphatic system, skin, soft tissue or bone and systemic disease.

Which of the following thermally dimorphic fungi causes a disease known as Cave disease, Darling's disease or Ohio valley disease?

  1. Blastomyces dermatitidis

  2. Sporothrix schenckii

  3. Histoplasma capsulatum

  4. Coccidiodes immitis


Correct Option: C
Explanation:

Histoplasma capsulatum fungus causes histoplasmosis. It is also known as Cave disease, Darling's disease or Ohio valley disease. The disease affects primarily the lungs and is common among AIDS patients due to their suppressed immunity.

Which of the following diseases is an emerging disease in which obligate intracellular bacteria infect and kill white blood cells?

  1. Babesia

  2. Ehrlichiosis

  3. Encephalitozoon cuniculi

  4. Peliosis hepatis


Correct Option: B
Explanation:

Ehrlichiosis is an emerging bacterial disease in which obligate intracellular bacteria infect and kill white blood cells. It is caused by Anaplasma phagocytophilum, Ehrlichia ewingii, Ehrlichia chaffeensis or Neorickettsia sennetsu.

Which of the following re-emergent pathogens cause(s) polio-like syndrome or permanent paralysis?

  1. Henipavirus

  2. Prions

  3. Coccidioides immitis

  4. Enterovirus 71


Correct Option: D
Explanation:

Enterovirus 71 causes polio-like syndrome or permanent paralysis. This virus appears to have evolved only recently with the first known strain isolated in 1965.

Typhoid Mary was responsible for at least 10 outbreaks of typhoid fever. Which of the following types of carriers was she?

  1. Active carrier

  2. Chronic carrier

  3. Casual carrier

  4. None of the above


Correct Option: B
Explanation:

Typhoid Mary was a chronic carrier and was presumed to have infected 51 people, three of whom died. She harboured the pathogen inside her body for a long time.

Which of the following organisms was responsible for the worldwide pandemic that occurred in 1918-1919 and took 20 million lives?

  1. Smallpox virus

  2. Tuberculosis virus

  3. Influenza virus

  4. Dengue virus


Correct Option: C
Explanation:

The causative organism for 1918-1919 pandemic was influenza virus. It took 20 million lives.

Which of the following statements is true about herd immunity?

  1. In herd immunity, full herd is immunised against a pathogen.

  2. In herd immunity, only some of the inhabitants are immunised and others develop immunity themselves.

  3. Herd immunity means that the whole herd is naturally immune to an infection.

  4. Herd immunity refers to the susceptibility index of the herd.


Correct Option: B
Explanation:

In herd immunity, only some of the inhabitants are immunised and others develop immunity themselves. It is a form of indirect protection from infectious diseases that occurs when a large percentage of population has become immune to an infection. It provides a measure of protection for individuals who are not immune.

Which of the following fungi produces a food-borne mycotoxin called aflatoxin?

  1. Alternaria

  2. Aspergillus parasiticus

  3. Fusarium moniliforme

  4. Aspergillus ochraceus


Correct Option: B
Explanation:

Aspergillus parasiticus secretes aflatoxins. It is frequently found in tree nuts, peanuts, maize, sorghum and other oilseeds, including corn and cottonseeds. 

Which of the following immunities is exemplified by the sentence that in some parts of Africa, resistance to Plasmodium falciparum malaria is seen?

  1. Individual immunity

  2. Species immunity

  3. Racial immunity

  4. Acquired immunity


Correct Option: C
Explanation:

Racial immunity is when different races within a species show differences in susceptibility to infections. In some parts of Africa, resistance to Plasmodium falciparum malaria is an example of racial immunity.

Which of the following explains racial immunity?

  1. Mutation

  2. Selection

  3. Adaptation

  4. Inheritance


Correct Option: B
Explanation:

Racial immunity is a natural immunity shared by most of the members of a genetically related population. In humans, it is explained through selectivity and survival.

In little girls, the infectant for vulvovaginitis may be acquired by

  1. fomites

  2. contaminated food

  3. contaminated water

  4. droplet nuclei


Correct Option: A
Explanation:

In little girls, vulvovaginitis is acquired through fomites. Bedclothes, towel and common bath tubs may spread the infection.

Transferrins form a part of external defense mechanism. They are located in

  1. saliva

  2. milk

  3. serum

  4. tears


Correct Option: C
Explanation:

Transferrins are found in serum. These are proteins with antibacterial activity and are iron-binding blood plasma glycoproteins that control the level of free iron in biological fluids. 

Which of the following food-borne pathogens can lead to secondary Guillain-Barré syndrome and periodontitis?

  1. Clostridium perfringens

  2. Campylobacter jejuni

  3. Listeria monocytogenes

  4. Enterohaemorrhagic E. coli


Correct Option: B
Explanation:

Campylobacter jejuni is recognised as one of the main causes of bacterial food-borne disease in many developed countries. This pathogen can be the underlying cause of secondary Guillain-Barré syndrome and periodontitis.

Which of the following water-borne pathogens is not always acquired by drinking contaminated water?

  1. E. coli

  2. Leptospira

  3. Salmonella

  4. Shigella


Correct Option: B
Explanation:

Leptospira causes leptospirosis. It may not be always water-borne. It causes a non-intestinal disease where bacteremia and kidney damage takes place.

A person who had a disease and has recovered from it will act as a/an

  1. convalescent carrier

  2. healthy carrier

  3. casual carrier

  4. incubatory carrier


Correct Option: A
Explanation:

A person who had a disease and has recovered from it will act as a convalescent carrier. It is because he is still capable of transmitting the infectious agent to others.

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