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Muscular and Skeletal System of Human Beings

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Mr. Khanna met with a road accident. After examining his X ray, the doctor told him that the bones containing the bony sinuses have been fractured. Which among the following bones, the doctor must be referring to?

  1. Long bones

  2. Short bones

  3. Flat bones

  4. Sesamoid bones

  5. Irregular bones


Correct Option: E
Explanation:

Irregular bones are irregular and complicated. Often this irregular shape is due to their many centers of ossification or because they contain bony sinuses. The bones of the spine, pelvis and some bones of the skull are irregular bones. Examples include the ethmoid and sphenoid bones. 

Which of the following is mainly used as a dietary supplement for treatment of people suffering from osteoarthritis?

  1. Hyaluronan

  2. Keratan sulfate

  3. Dermatan sulfate

  4. Chondroitin sulfate

  5. Heparin


Correct Option: D
Explanation:

Chondroitin sulfate is an important structural component of cartilage and provides much of its resistance to compression. Along with glucosamine, chondroitin sulfate has become a widely used dietary supplement for treatment of osteoarthritis.

The muscle that is most popular among bodybuilders as lats muscle is the _________.

  1. latissimus dorsi muscle

  2. deltoid muscle

  3. triceps brachii muscle

  4. biceps brachii

  5. erector spinae


Correct Option: A
Explanation:

The latissimus dorsi is the larger, flat dorso-lateral muscle on the trunk. Latissimi dorsi are commonly known as lats, especially among bodybuilders. These muscles are responsible for extension, adduction and internal rotation of the shoulder joint.

There are several principle differences between human male and female pelvis. Which among the following differences regarding the human male and female pelvis is false?

  1. The female pelvis is larger while the male pelvis is taller.

  2. The female inlet is more heart in shape, while the male inlet is more oval shaped.

  3. The greater sciatic notch is wider in females than females.

  4. The iliac crests are higher and more pronounced in males than females.

  5. The male sacrum is long and narrow, while the female sacrum is shorter and wider.


Correct Option: B
Explanation:

The female inlet is larger and oval in shape, while the male sacral promontory projects further (i.e. the male inlet is more heart-shaped).

The reciprocally concave-convex surfaces are the characteristic feature of ________.

  1. gliding joint

  2. hinge joint

  3. pivot joints

  4. saddle joint

  5. ball and socket joint


Correct Option: D
Explanation:

In a saddle joint, the opposing surfaces are reciprocally concave-convex. The best example of saddle joints are first carpo metacarpal joints (Articulationes carpometacarpeae), joints between femur and patella and the calcaneocuboid joints.

Which among the following is a rare inherited disorder of the bones of human beings?

  1. Osteopetrosis

  2. Osteoporosis

  3. Osteopenia

  4. Osteomyelitis

  5. Osteomalacia


Correct Option: A
Explanation:

Osteopetrosis is an extremely rare inherited disorder whereby the bones harden and become denser. It can cause bones to dissolve and break.

The most crucial stabilising muscle of the lower leg in humans is _______.

  1. gastrocnemius muscle

  2. tibialis posterior muscle

  3. soleus muscle

  4. tibialis anteriormuscles

  5. liopsoas muscle


Correct Option: B
Explanation:

The tibialis posterior is the most central of all the leg muscles, and is located in the posterior compartment of the leg. It is the key stabilising muscle of the lower leg.

Which among the following cell types of the bone marrow stroma is important in wound healing?

  1. Fibroblast

  2. Monovacuolar cells

  3. Plurivacuolar cells

  4. Induced pluripotent stem cells

  5. Osteoclast


Correct Option: A
Explanation:

A fibroblast is a type of cell that synthesises the extracellular matrix and collagen, the structural framework (stroma) for animal tissues and plays a critical role in wound healing. Fibroblasts are the most common cells of connective tissue in animals.

The conversion of cartilage into bone occurs in the five zones. In which of the following zones, the chondrocytes die?

  1. Zone of reserve cartilage

  2. Zone of cell proliferation

  3. Zone of cell hypertrophy

  4. Zone of calcification

  5. Zone of bone deposition


Correct Option: E
Explanation:

Within each column, the walls between the lacunae break down and the chondrocytes die. This converts each column into a longitudinal channel, which is immediately invaded by blood vessels and marrow from the marrow cavity. Osteoblasts line up along the walls of these channels and begin depositing concentric lamellae of matrix, while osteoclasts dissolve the temporarily calcified cartilage.

Which among the following statements does not characterise skeletal striated muscle of the body?

  1. The sarcomere is the basic machinery of the muscle contraction.

  2. The myofibrils are long protein bundles containing mitochondria.

  3. The muscle fiber contains a smooth endoplasmic reticulum between the myofibrils.

  4. Contracting muscles produce vibration and sound.

  5. Once a cell is sufficiently stimulated, the cell's sarcoplasmic reticulum releases ionic calcium.


Correct Option: C
Explanation:

While the muscle fiber does not have a smooth endoplasmic reticulum, it contains a sarcoplasmic reticulum. The sarcoplasmic reticulum surrounds the myofibrils and holds a reserve of the calcium ions needed to cause a muscle contraction.

The cells playing a crucial role in making, remodeling and repairing of a bone are _______.

  1. osteocytes

  2. lining cells

  3. osteoblasts

  4. osteoclasts

  5. stromal cells


Correct Option: C
Explanation:

Osteoblasts are bone cells that are responsible for the formation of new bone. The osteoblasts are much smaller; they only have one nucleus. Osteoblasts also work in groups to form new bone. Osteoblasts are important because it allows the bones to be made, remodeled and repaired.

After thorough checkup, doctor told a couple that their son is suffering from a disease in which the patient is born with defective connective tissue without the ability to make it. Which among the following diseases the doctor must be talking about?

  1. Paget's disease of bone

  2. Osteitis pubis

  3. Osteogenesis imperfecta

  4. Osteochondromas

  5. Condensing osteitis


Correct Option: C
Explanation:

Osteogenesis imperfecta is a congenital bone disorder characterised by brittle bones that are prone to fracture. People with OI are born with defective connective tissue, or without the ability to make it, usually because of a deficiency of Type-I collagen.

Which among the following statements regarding the cardiac muscles of the body is incorrect?

  1. The diad is located at the sarcomere Z-line.

  2. The diad juxtaposes an inlet for the action potential near a source of Ca2+ ions.

  3. Intercalated discs connect the single cardiac myocytes to an electrochemical syncytium.

  4. Cardiac muscle requires intracellular calcium ions for contraction to occur.

  5. Cardiac muscle cells rely on an available blood and electrical supply to deliver oxygen.


Correct Option: D
Explanation:

In contrast to skeletal muscle, cardiac muscle requires extracellular calcium ions for contraction to occur. Like skeletal muscle, the initiation and upshoot of the action potential in ventricular muscle cells is derived from the entry of sodium ions across the sarcolemma in a regenerative process.

Five ligaments are supposed to be most important in stabilizing the thumb. The ligament responsible for abduction, extension, and pronation of the thumb is _______.

  1. anterior oblique ligament

  2. ulnar collateral ligament

  3. first intermetacarpal ligament

  4. dorsoradial ligament

  5. Posterior oblique ligment


Correct Option: B
Explanation:

An extracapsular ligament has its origin on the flexor retinaculum and is inserted on the ulnopalmar tubercle of the first metacarpal. It is taut in abduction, extension and pronation and often found elongated in connection to CMC joint arthritis. 

A fibrocartilage articular disc is associated with which of the following joints?

  1. Glenohumeral joint

  2. Acromioclavicular joint

  3. Sternoclavicular joint

  4. Midcarpal joint

  5. Carpometacarpal joints


Correct Option: C
Explanation:

The sternoclavicular articulation is a synovial double-plane joint. It is composed of two portions separated by an articular disc which is made from fibrocartilage. This disk also allows motion between the sternum (manubrium) and itself during protraction and retraction of the scapula.

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