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Organic Chemistry Test

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Which of the following techniques of chromatography is performed on a sheet of glass, plastic, or aluminum foil?

  1. Column chromatography

  2. Planar chromatography

  3. Paper chromatography

  4. Thin layer chromatography


Correct Option: D
Explanation:

Thin layer chromatography (TLC) is a chromatography technique used to separate mixtures. Thin layer chromatography is performed on a sheet of glass, plastic, or aluminum foil, which is coated with a thin layer of adsorbent material, usually silica gel, aluminium oxide, or cellulose (blotter paper).

The sample components in partition chromatography are termed as

  1. a chromatograph

  2. the eluate

  3. the eluent

  4. the solute


Correct Option: D
Explanation:

The solute refers to the sample components in partition chromatography.

Which of the following drugs acts as an antihistamine in the body?

  1. Allegra

  2. Adipex-P

  3. Adderall

  4. Actiq


Correct Option: A
Explanation:

Allegra (fexofenadine) is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.Allegra is used to treat the symptoms of seasonal allergies (hay fever) in adults and children.

Chromatography may be preparative or analytical. In which of the following chromatographic techniques, both the stationary and mobile phases are liquids?

  1. Reversed-phase chromatography

  2. Pyrolysis gas chromatography

  3. Fast protein liquid chromatography

  4. Countercurrent chromatography


Correct Option: D
Explanation:

Countercurrent chromatography (CCC) is a type of liquid-liquid chromatography, where both the stationary and mobile phases are liquids. The operating principle of CCC equipment requires a column consisting of an open tube coiled around a bobbin.

Which of the following methods is used for determining molecular geometry of the compounds?

  1. Nuclear magnetic resonance

  2. Elemental analysis

  3. Mass spectrometry

  4. Crystallography


Correct Option: D
Explanation:

Crystallography is an unambiguous method for determining molecular geometry, the proviso being that single crystals of the material must be available and the crystal must be representative of the sample. Highly automated software allows a structure to be determined within hours of obtaining a suitable crystal.

The chromatography technique used for the separation of stereoisomers is

  1. ion exchange chromatography

  2. size-exclusion chromatography

  3. reversed-phase chromatography

  4. chiral chromatography


Correct Option: D
Explanation:

Chiral chromatography involves the separation of stereoisomers.To enable chiral separation to take place, either the mobile phase or the stationary phase must be made chiral, giving differing affinities between the analytes.

The aim of chromatography is to separate the components of a mixture. Which of the following chromatography processes is always carried out in a column?

  1. Gas chromatography

  2. Liquid chromatography

  3. Affinity chromatography

  4. Supercritical fluid chromatography


Correct Option: A
Explanation:

Gas chromatography (GC), also known as Gas-Liquid chromatography, (GLC), is a separation technique in which the mobile phase is a gas. Gas chromatography is always carried out in a column which is typically packed or capillary.

Isomers are compounds with the same molecular formulae but different structural formulae. Which among the following is an isomer of naphthalene?

  1. Polyfluorenes

  2. The phenylene group

  3. Pyrene

  4. Azulene


Correct Option: D
Explanation:

Azulene is an organic compound and an isomer of naphthalene. 

Biofuel is a fuel obtained from biomass.Which of the following biofuels is derived from renewable feedstock ?

  1. Vegetable oil

  2. Green diesel

  3. Biodiesel

  4. Ethanol fuel


Correct Option: B
Explanation:

Green diesel is a form of diesel fuel which is derived from renewable feedstock rather than the fossil feedstock used in most diesel fuels. Green diesel feedstock can be sourced from a variety of oils including canola, algae, jatropha and salicornia in addition to tallow.

The biofuel obtained from wood and various types of grass is

  1. 2,5-dimethylfuran

  2. dimethyl ether

  3. ethanol fuel

  4. cellulosic ethanol


Correct Option: D
Explanation:

Cellulosic ethanol is a biofuel produced from wood, grasses, or the non-edible parts of plants. It is a type of biofuel produced from lignocellulose, a structural material that comprises much of the mass of plants. 

Which of the following biofuels is used in racing cars ?

  1. Cellulosic ethanol

  2. Algae fuel

  3. Biohydrogen

  4. BIomethanol


Correct Option: D
Explanation:

Biomethanol is an alternate fuel for internal combustion and other engines, either in combination with gasoline or directly (neat). It is used in racing cars and in China.

Which of the following compounds is used as an intermediate for the synthesis of certain analgesics and antipsychotic drugs?

  1. Benzazepines

  2. Dibenzazepine

  3. Polyaniline

  4. Polythiophenes


Correct Option: B
Explanation:

Dibenzazepine (iminostilbene) is a chemical compound with two benzene rings fused to an azepine group. Dibenzazepine is used as an intermediate for the synthesis of specific analgesic and antipsychotic agents.

High stability, moderate band gap and low redox potential are the characteristics of

  1. Poly(3,4-ethylenedioxythiophene)

  2. polyphenylene sulfide

  3. Polyacetylene

  4. Polypyrrole


Correct Option: A
Explanation:

Poly(3,4-ethylenedioxythiophene) is a conducting polymer based on 3,4-ethylenedioxylthiophene or EDOT monomer. Advantages of this polymer are optical transparency in its conducting state, high stability, moderate band gap and low redox potential.

Which of the following compounds has a random, amorphous structure ?

  1. Hemicellulose

  2. Pectin

  3. Lignin

  4. Microfibrils


Correct Option: A
Explanation:

A hemicellulose is a heteropolymer present in almost all plant cell walls. It has a random, amorphous structure with little strength. It is easily hydrolyzed by dilute acid or base as well as myriad hemicellulase enzymes.

Which of the following compounds is associated with fouling fish and bad breath?

  1. Dimethylamine

  2. Methylamine

  3. Trimethylamine

  4. Methylhexanamine


Correct Option: C
Explanation:

Trimethylamine is an flammable tertiary amine. It is a product of decomposition of plants and animals. It is the substance mainly responsible for the odour often associated with fouling fish, infection and bad breath. It is also associated with taking large doses of choline and carnitine.

Which of the following amino acids is coaded by UUU and UUC codons?

  1. Tyrosine

  2. Phenylalanine

  3. Tryptophan

  4. Valine


Correct Option: B
Explanation:

Phenylalanine is an α-amino acid . This essential amino acid is classified as nonpolar because of the hydrophobic nature of the benzyl side chain. L-Phenylalanine (LPA) is an electrically neutral amino acid.The codons for L-phenylalanine are UUU and UUC.

Neurotransmitters allow the transmission of signals from one neuron to the next across synapses. Which among the following is not a neurotransmitter?

  1. Epinephrine

  2. Norepinephrine

  3. Melanin

  4. Dopamine


Correct Option: C
Explanation:

Melanin is a pigment that is ubiquitous in nature, being found in most organisms. In animals melanin pigments are derivatives of the amino acid tyrosine.

Mrs Shukla had been taking certain medicine for some time. Now she has completely lost her appetite. She must have been taking -----------------------.

  1. anorectic

  2. bronchodilator

  3. decongestant

  4. entactogen


Correct Option: A
Explanation:

An anorectic is a dietary supplement and/or drug which reduces appetite, food consumption, and as a result, causes weight loss to occur.

Sugar obtained from wood is

  1. xylose

  2. mannose

  3. galactose

  4. rhamnose


Correct Option: A
Explanation:

Xylose is a sugar first isolated from wood, and named for it. Xylose is classified as a monosaccharide of the aldopentose type, which means that it contains five carbon atoms and includes an aldehyde functional group. It is the precursor to hemicellulose,

Caprolactam is a derivative of

  1. carbazole

  2. indole

  3. azepines

  4. azepane


Correct Option: D
Explanation:

Azepane is a saturated heterocycle, containing one nitrogen atom in seven-membered ring. A well known azepane derivative is caprolactam.

Which of the following pigments imparts pink to red colours to hair?

  1. Benzothiazine

  2. Eumelanin

  3. Pheomelanin

  4. Neuromelanin


Correct Option: C
Explanation:

Pheomelanin is  found in hair and skin and in  both the lighter-skinned humans and darker skinned humans. Pheomelanin imparts a pink to red hue and, thus is found in particularly large quantities in red hair.

Anti-depressants are the psychiatric medications used to treat mood disorders. Which among the following can be excluded from the category of anti-depressants?

  1. Desipramine

  2. Doxepin

  3. Imipramine

  4. None of the above


Correct Option: D
Explanation:

All are used as anti-depressants.

Which of the following compounds is a sugar alcohol?

  1. Arabinose

  2. Fucose

  3. Fuculose

  4. Galactitol


Correct Option: D
Explanation:

Galactitol is a sugar alcohol, the reduction product of galactose.It is produced from galactose in a reaction catalyzed by aldose reductase. Galactose itself comes from the metabolism of the disaccharide lactose into glucose and galactose.

Bioplastics are the form of plastics derived from renewable biomass sources. Which of the following bioplastics are produced from the cane sugar?

  1. Starch-based plastics

  2. Cellulose bioplastics

  3. Polylactic acid (PLA) plastics

  4. Polyamide 11


Correct Option: C
Explanation:

Polylactic acid (PLA) is a transparent plastic produced from cane sugar or glucose. It not only resembles conventional petrochemical mass plastics (like PE or PP) in its characteristics, but  can also be processed easily on standard equipment that already exists for the production of conventional plastics.

Loop diuretics are used to treat heart failure. Which among the following is a loop diuretic?

  1. Abilify

  2. Accutane

  3. Insulin

  4. Lasix


Correct Option: D
Explanation:

Lasix is a loop diuretic (water pill) that prevents one's body from absorbing too much salt, allowing the salt to instead be passed in the urine.

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