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Chemistry Test

Description: This test is based on certain topics from organic chemistry.
Number of Questions: 25
Created by:
Tags: dinitrogen phosphorus oxoa acids interhalogens and sulphur Chemicals in Medicine and Health-Care Therapeutic Action of Different Classes of Drugs Advanced Materials Classification of Drugs Proteins
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Which among the following is not used for general anesthesia?

  1. Desflurane

  2. Nitrous oxide

  3. Sevoflurane

  4. Ionones


Correct Option: D
Explanation:

The ionones are a series of closely related chemical substances that are part of a group of compounds known as rose ketones, which also includes damascones and damascenones. Ionones are aroma compounds found in a variety of essential oils, including rose oil.

Antihistamines are used to treat allergies. Which of the following is a first generation antihistamine?

  1. Azines

  2. Nicotinamide

  3. Pyridoxal

  4. Mepyramine


Correct Option: D
Explanation:

Mepyramine, also known as pyrilamine, is a first generation antihistamine, targeting the H1 receptor.However, it rapidly permeates the brain often causing drowsiness. It also has anticholinergic properties.

An inhalational anaesthetic has general anaesthetic properties. Which of the following is used for inhalational anaesthesia?

  1. Isobenzofuran

  2. Borneol

  3. Isoflurane

  4. Isoindole


Correct Option: C
Explanation:

Isoflurane is a halogenated ether used for inhalational anaesthesia. Together with enflurane and halothane, it replaced the flammable ethers used in the pioneer days of surgery.

Which among the following pigments is a red crystalline solid with a metallic lustre?

  1. Cryptoxanthin

  2. β-Carotene

  3. Lycopene

  4. Xanthophylls


Correct Option: A
Explanation:

Cryptoxanthin is a natural carotenoid pigment. It has been isolated from a variety of sources including the petals and flowers of plants in the genus Physalis.In a pure form, cryptoxanthin is a red crystalline solid with a metallic lustre.

Which of the following is a natural constituent of crude oil?

  1. Benzene

  2. Pyridine

  3. Sulphapyridine

  4. Carbon disulfide


Correct Option: A
Explanation:

Benzene is a natural constituent of crude oil, and is one of the most basic petrochemicals. Benzene is an aromatic hydrocarbon and the second [n]-annulene ([6]-annulene), a cyclic hydrocarbon with a continuous pi bond. It is also related to the functional group of aromatic hydrocarbons (arene) which is a generalized structure of benzene.

Directions: The following question has four choices out of which ONLY ONE is correct.

Which of the following compounds is used as a precursor to teflon and refrigerants?

  1. Chloroform

  2. Cyclopropane

  3. Diethyl ether

  4. Ethylene


Correct Option: A
Explanation:

Chloroform is the organic compound with formula CHCl3 . The colourless, sweet-smelling, dense liquid is a trihalomethane, and is considered somewhat hazardous. Several million tons are produced annually as a precursor to teflon and refrigerants.

Which of the following is not an essential amino acid?

  1. Isoleucine

  2. Asparagine

  3. Leucine

  4. Lysine


Correct Option: B
Explanation:

Asparagine is one of the 20 most common natural amino acids on Earth. It has carboxamide as the side-chain's functional group. It is not an essential amino acid. Its codons are AAU and AAC.

Which of the following is N-methylated analogue of phenobarbital?

  1. Butabarbital

  2. Aprobarbital

  3. Methylphenobarbital

  4. Benzobarbital


Correct Option: C
Explanation:

Methylphenobarbital is a drug which is a barbiturate derivative. It is used as a sedative, anxiolytic and anticonvulsant. It is the N-methylated analogue of phenobarbital, and has similar indications, therapeutic value, and tolerability.

Anticoagulants reduce the process of blood clotting. Which of the following is a anticoagulant?

  1. Fetal fibronectin

  2. Heparin

  3. Actin

  4. Vinculin


Correct Option: B
Explanation:

Heparin is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule. It can also be used to form an inner anticoagulant surface on various experimental and medical devices such as test tubes and renal dialysis machines.

Among the following ____________ protein is found in bacteria.

  1. Actin alpha 1

  2. Beta-actin

  3. ACTG1

  4. MreB


Correct Option: D
Explanation:

MreB is a protein found in bacteria that has been identified as a homologue of actin, as indicated by similarities in tertiary structure and conservation of active site peptide sequence.

The skin is the largest organ in the body. Its outer layer is made up of ___________ protein.

  1. endostatin

  2. angiostatin

  3. keratin

  4. gelatin


Correct Option: C
Explanation:

Keratin refers to a family of fibrous structural proteins. Keratin is the key structural material making up the outer layer of human skin. It is also the key structural component of hair and nails.

Lysine is an amino acid. Which of the following compounds is an intermediate in its metabolism ?

  1. Saccharopine

  2. Allysine

  3. α-Aminoadipic acid

  4. α-Ketobutyric acid


Correct Option: A
Explanation:

Saccharopine is an intermediate in the metabolism of amino acid lysine. It is a precursor of lysine in the alpha-aminoadipate pathway which occurs in a few lower fungi, the higher fungi, and euglenids.

The acid found in vomitting is

  1. butyric acid

  2. 4-Hydroxyphenylpyruvic acid

  3. homogentisic acid

  4. cysteine sulfinic acid


Correct Option: A
Explanation:

Butyric acid is found in butter, parmesan cheese, vomit, and as a product of anaerobic fermentation (including in the colon and as body odour). It has an unpleasant smell and acrid taste, with a sweetish aftertaste (similar to ether).

Blood clotting is an important part of hemostasis. The protein participating in blood clotting is

  1. decorin

  2. fibronectin

  3. integrins

  4. fibrin


Correct Option: D
Explanation:

Fibrin is a fibrous protein involved in the clotting of blood and is non-globular. It is a fibrillar protein that is polymerised to form a mesh that forms a hemostatic plug or clot (in conjunction with platelets) over a wound site.

The pili are the hairlike outgrowths found on the surface of bacteria. Which of the following enzymes catalyze the assembly of pilins into pili?

  1. Sortase

  2. Translocase

  3. Polyphosphate kinase

  4. F-ATPase


Correct Option: A
Explanation:

Sortase refers to a group of prokaryotic enzymes which catalyze the assembly of pilins into pili, and the anchoring of pili to the cell wall. They act as both proteases and transpeptidases.

A neuron has one axon connecting it with other neurons or with muscle or gland cells. Which of the following proteins is involved in regeneration of injured axons?

  1. Histatins

  2. Rabaptin

  3. Innexin

  4. Colipase


Correct Option: B
Explanation:

Rabaptin is a key protein involved in regeneration of injured axons. Regeneration of injured axons at neuromuscular junctions is regulated by extra-cellular protein factors that promote neurite outgrowth.

Histidine is an essential amino acid. The ____________ organic compound is an intermediate in its metabolism .

  1. urocanic acid

  2. formiminoglutamic acid

  3. 1-Pyrroline-5-carboxylic acid

  4. 3-Phosphoglyceric acid


Correct Option: B
Explanation:

Formiminoglutamic acid (FIGLU) is an intermediate in the metabolism of histidine. The FIGLU test is used to identify deficiency of vitamin B12 or folate deficiency or liver disease.

The protein found in the bone which binds sodium is

  1. fibronectin

  2. laminins

  3. osteonectin

  4. selectins


Correct Option: C
Explanation:

Osteonectin is a glycoprotein in the bone that binds sodium. It is secreted by osteoblasts during bone formation, initiating mineralization and promoting mineral crystal formation. Osteonectin also shows affinity for collagen in addition to bone mineral calcium.

Neurotransmitters are endogenous chemicals secreted in the body. Which of the following amino acids acts as a neurotransmitter?

  1. Cysteine

  2. Glutamic acid

  3. Glycine

  4. Serine


Correct Option: B
Explanation:

Glutamic acid is one of the 20 proteinogenic amino acids and its codons are GAA and GAG. It is a non-essential amino acid. It is an important neurotransmitter that plays a key role in long-term potentiation and is important for learning and memory.

Glycine is the smallest amino acid. Its metabolite is

  1. creatine

  2. glycocyamine

  3. phosphocreatine

  4. creatinine


Correct Option: B
Explanation:

Glycocyamine is a metabolite of glycine in which the amino group has been converted into a guanidine. It is a direct precursor of creatine and is used as a supplement. However, the metabolism of creatine from glycocyamine in the liver causes a depletion of methyl groups.

Which among the following is a mitochondrial inner membrane protein ?

  1. A membrane protein

  2. An uncoupling protein

  3. The Fusion proteins

  4. A lipid-anchored protein


Correct Option: B
Explanation:

An uncoupling protein is a mitochondrial inner membrane protein that can dissipate the proton gradient before it can be used to provide the energy for oxidative phosphorylation.

Among the following compounds ___________ is present within the retina of the eye.

  1. lutein

  2. zeaxanthin

  3. neoxanthin

  4. violaxanthin


Correct Option: B
Explanation:

Zeaxanthin is one of the two primary xanthophyll carotenoids contained within the retina of the eye. Within the central macula, zeaxanthin is the dominant component, whereas in the peripheral retina, lutein predominates.

Tobacco is a valuable cash crop. Which of the following constitutes about 0.6 -3.0% of the dry weight of tobacco?

  1. Acetaldehyde

  2. Nicotine

  3. Isoniazid

  4. 4-Methylpyridine


Correct Option: B
Explanation:

Nicotine is an alkaloid found in the nightshade family of plants that constitutes approximately 0.6-3.0% of the dry weight of tobacco, with biosynthesis taking place in the roots and accumulation occurring in the leaves. It functions as an antiherbivore chemical with particular specificity to insects.

Among the following _____________ is a/an short-acting barbiturate .

  1. phenobarbital

  2. pentobarbital

  3. secobarbital

  4. amobarbital


Correct Option: B
Explanation:

Pentobarbital is a short-acting barbiturate that was first synthesized in 1928. Pentobarbital is available as both a free acid and a sodium salt, the former of which is only slightly soluble in water and ethanol.

Obstetrical Analgesia obliterates the pain of childbirth. Which of the following is used as an inhaled obstetrical analgesic?

  1. Trichloroethylene

  2. Methoxypropane

  3. Methoxyflurane

  4. Halothane


Correct Option: A
Explanation:

Trichloroethylene is a chlorinated hydrocarbon commonly used as an industrial solvent. It is a clear non-flammable liquid with a sweet smell.It is used as a volatile anesthetic and as an inhaled obstetrical analgesic in millions of patients.

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