0

Organic Chemistry Test

Description: This test contains 25 multiple choice questions on organic chemistry.
Number of Questions: 25
Created by:
Tags: Drugs medicimes paracetamol etc Chemicals in Medicine and Health-Care Therapeutic Action of Different Classes of Drugs Dyes Classification of Drugs
Attempted 0/25 Correct 0 Score 0

An antipruritic agent helps to relieve the discomfort associated with itching. Which of the following local anesthetics is used as an antipruritic?

  1. Procaine

  2. Tetracaine

  3. Cocaine

  4. Lidocaine


Correct Option: B
Explanation:

Tetracaine is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.

Proctosedyl is a topical hemorrhoid cream. Which among the following is present as an active ingredient in Proctosedyl?

  1. Prilocaine

  2. Bupivacaine

  3. Mepivacaine

  4. Cinchocaine


Correct Option: D
Explanation:

Cinchocaine is an amide local anesthetic. It is an active ingredient in some topical hemorrhoid creams such as Proctosedyl.

Methoxyflurane is used as a volatile inhalational anesthetic. It was first synthesized by

  1. Georgius Agricola

  2. William T. Miller

  3. Sidney Altman

  4. Johan August Arfwedson


Correct Option: B
Explanation:

Methoxyflurane is a halogenated ether that was in clinical use as a volatile inhalational anesthetic from its introduction by Joseph F. Artusio et al in 1960 until around 1974. It was first synthesized in the late 1940s by William T. Miller and his team of chemists following their involvement in the Manhattan Project.

Which of the following drugs does not contain halogens?

  1. Halothane

  2. Isoflurane

  3. Desflurane

  4. None of the above


Correct Option: D
Explanation:

All of the above contain halogens.

Which of the following can be excluded from the category of barbiturate drugs?

  1. Methohexital

  2. Thiamylal

  3. Diazepam

  4. Sodium thiopental


Correct Option: C
Explanation:

Diazepam is a benzodiazepine derivative drug. It is commonly used for treating anxiety, insomnia, seizures including status epilepticus, muscle spasms (such as in cases of tetanus), and Ménière's disease.

Anaesthesia affecting only a large part of the body is called as

  1. Local anesthesia

  2. Regional anaesthesia

  3. General anaesthesia

  4. Dissociative anesthesia


Correct Option: B
Explanation:

Regional anaesthesia is anaesthesia affecting only a large part of the body, such as a limb or the lower half of the body. Regional anaesthetic techniques can be divided into central and peripheral techniques.

The branch of medicine dealing with the anatomy, physiology and diseases of the eye is known as

  1. Dermatology

  2. Radiology

  3. Oncology

  4. Ophthalmology


Correct Option: D
Explanation:

Ophthalmology is the branch of medicine which deals with the anatomy, physiology and diseases of the eye. The term ophthalmologist refers to a specialist in medical and surgical eye problems.

Which among the following is generally used in veterinary medicine?

  1. Propofol

  2. Alfentanil

  3. Fentanyl

  4. Remifentanil


Correct Option: A
Explanation:

Propofol is a short-acting, intravenously administered hypnotic agent. Its uses include the induction and maintenance of general anesthesia, sedation for mechanically ventilated adults, and procedural sedation. Propofol is also commonly used in veterinary medicine.

Which of the following dyes is used as a complexometric indicator ?

  1. Calcein

  2. Carboxyfluorescein

  3. Eosin

  4. Erythrosine


Correct Option: A
Explanation:

Calcein is a fluorescent dye with excitation and emission wavelengths of 495/515 nm, respectively. It is used as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium. It has the appearance of orange crystals.

Which of the following is considered to be the prototypical opioid?

  1. Methadone

  2. Morphine

  3. Nalbuphine

  4. Oxycodone


Correct Option: B
Explanation:

Morphine is a potent opiate analgesic medication and is considered to be the prototypical opioid.

Which of the following dyes are generally used as pH indicators and as biological stains?

  1. Acid dyes

  2. Basic dyes

  3. Direct dyes

  4. Vat dyes


Correct Option: C
Explanation:

Direct or substantive dyeing is normally carried out in a neutral or slightly alkaline dyebath, at or near boiling point, with the addition of either sodium chloride (NaCl) or sodium sulfate (Na2SO4). Direct dyes are used on cotton, paper, leather, wool, silk and nylon. They are also used as pH indicators and as biological stains.

Enflurane is a halogenated ether. It was developed by

  1. Ross Terrell

  2. Richard Wilhelm Heinrich Abegg

  3. Frederick Accum

  4. Peter Agre


Correct Option: A
Explanation:

Enflurane (2-chloro-1, 1, 2,- trifluoroethyl-difluoromethyl ether) is a halogenated ether that was commonly used for inhalational anesthesia during the 1970s and 1980s. Developed by Ross Terrell in 1963, it was first used clinically in 1966.

Adverse effects of local anesthesia are generally referred to as local anesthetic toxicity. Which of the following statements regarding the local anesthetic toxicity is wrong?

  1. The anesthetic toxicity advesely affects the nervous system

  2. Local anesthetic drugs do not affect the heart

  3. Toxicity can occur with any local anesthetics as an individual reaction by that patient

  4. Direct infiltration of local anesthetic into skeletal muscle will cause temporary paralysis of the muscle


Correct Option: B
Explanation:

Local anesthetic drugs are toxic to the heart (where they cause arrhythmia) and brain (where they may cause unconsciousness and seizures). Arrhythmias may be resistant to defibrillation and other standard treatments, and may lead to loss of heart function and death.

A dye is a coloured substance having affinity to the substrate to which it is being applied. Most natural dyes are ______________.

  1. Sulfur dyes

  2. Disperse dyes

  3. Reactive dyes

  4. Mordant dyes


Correct Option: D
Explanation:

Mordant dyes require a mordant, which improves the fastness of the dye against water, light and perspiration. The choice of mordant is very important as different mordants can change the final colour significantly. Most natural dyes are mordant dyes and there is, therefore, a large literature base describing dyeing techniques.

Among the following, ___________ is a semi-synthetic opioid drug.

  1. Sufentanil

  2. Buprenorphine

  3. Butorphanol

  4. Heroin


Correct Option: D
Explanation:

Heroin is a semi-synthetic opioid drug synthesized from morphine, a derivative of the opium poppy. It is the 3,6-diacetyl ester of morphine (di-acetyl-morphine) and a morphine prodrug.

Intravenous (I.V.) drugs are injected directly into a blood vessel. Find a short acting intravenous anaesthetic agent out of the following.

  1. Lorazepam

  2. Midazolam

  3. Etomidate

  4. Ketamine


Correct Option: C
Explanation:

Etomidate is a short acting intravenous anaesthetic agent used for the induction of general anaesthesia and for sedation for short procedures such as reduction of dislocated joints and cardioversion.

Which of the following is a rapidly acting, non-depolarizing neuromuscular blocker?

  1. Oxymorphone

  2. Pentazocine

  3. Decamethonium

  4. Rapacuronium


Correct Option: D
Explanation:

Rapacuronium is a rapidly acting, non-depolarizing neuromuscular blocker formerly used in modern anaesthesia, to aid and enable endotracheal intubation, which is often necessary to assist in the controlled ventilation of unconscious patients during surgery and sometimes in intensive care.

Which among the following is a paralytic drug used to induce muscle relaxation ?

  1. Hydromorphone

  2. Levorphanol

  3. Pethidine

  4. Suxamethonium chloride


Correct Option: D
Explanation:

Suxamethonium chloride is a paralytic drug used to induce muscle relaxation and short term paralysis, usually to facilitate tracheal intubation.

Antiseptics are the substances which kill or inhibit the growth of microorganisms on the external surfaces of the body. Which among the following is used as a topical antiseptic?

  1. Fluorescein

  2. Fluorescein amidite

  3. Indian yellow

  4. Merbromin


Correct Option: D
Explanation:

Merbromin is a topical antiseptic used for minor cuts and scrapes. Merbromin is an organomercuric disodium salt compound and a fluorescein.

Which of the following is not an intermediate-duration non-depolarizing neuromuscular blocking agent?

  1. Mivacurium chloride

  2. Atracurium besylate

  3. Cisatracurium

  4. Vecuronium


Correct Option: A
Explanation:

Mivacurium chloride is a short-duration non-depolarizing neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs.

Copper containing pigment is called as

  1. Hemocyanins

  2. Hemolymph

  3. Hemoglobin

  4. Myoglobin


Correct Option: A
Explanation:

Hemocyanins are respiratory proteins in the form of metalloproteins containing two copper atoms that reversibly bind a single oxygen molecule (O2).

Which of the following is not used as a histological stain in biology?

  1. Cresyl violet

  2. Nile blue

  3. Indophenol

  4. Safranin


Correct Option: C
Explanation:

Indophenol is an artificial blue metachromatic dye, obtained by the action of phenol on certain nitrogenous derivatives of quinone. Indophenol resembles the colour indigo in appearance. It is often used to determine the presence of vitamin C, or ascorbic acid. it is not used as a histological stain in biology.

Which of the following is known as a laughing gas ?

  1. Nitrous oxide

  2. Sevoflurane

  3. Xenon

  4. Amobarbital


Correct Option: A
Explanation:

Nitrous oxide, commonly known as laughing gas or sweet air is a chemical compound with the formula N2O. It is a colourless non-flammable gas, with a slightly sweet odour and taste. It is used in surgery and dentistry for its anesthetic and analgesic effects.

The ______________ drug should not be given to the patients with renal failure.

  1. Alcuronium

  2. Doxacurium chloride

  3. Gallamine triethiodide

  4. Metocurine


Correct Option: D
Explanation:

Metocurine is a muscle relaxant through neuromuscular blockade. It is excreted entirely through the kidneys and, therefore, should not be used in patients with renal failure.

Among the following, ____________ acts as a reversible acetylcholinesterase inhibitor.

  1. Pancuronium

  2. Pipecuronium

  3. Neostigmine

  4. Naloxone


Correct Option: C
Explanation:

Neostigmine is a parasympathomimetic that acts as a reversible acetylcholinesterase inhibitor.

- Hide questions