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Human Diseases (Class XII)

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Chronic pancreatitis is a type of

  1. endocrinopathy

  2. exocrinopathy

  3. infectious disease

  4. genetic disorder


Correct Option: B
Explanation:

Chronic pancreatitis is a type of exocrinopathy. It is an exocrine disorder that causes extensive damage to the pancreas. It may lead to diabetes.

Which of the following viruses is sometimes associated with type 1 diabetes?

  1. Papilloma virus

  2. JC virus

  3. Coxsackie virus

  4. Dhori virus


Correct Option: C
Explanation:

Coxsackie virus has been associated with type 1 diabetes in some cases. It shares a sequence homology with type 1 diabetes, mellitus peptide.

Which of the following types of diabetes is characterised by insulin resistance?

  1. Type 1 DM

  2. Type 2 DM

  3. GDM

  4. LADA


Correct Option: B
Explanation:

Type 2 DM is characterised by insulin resistance. It may be combined with a relatively reduced insulin secretion.

Which of the following diseases is transmitted by tsetse fly?

  1. African sleeping sickness

  2. Chagas disease

  3. Leishmaniasis

  4. Babesiosis


Correct Option: A
Explanation:

African sleeping sickness is caused by Trypanosoma gambiense or T. brucei and is transmitted by tsetse fly

Which of the following organisms causes jock itch of the groin?

  1. Tinea pedis

  2. Tinea unguium

  3. Tinea cruris

  4. Tinea corporis


Correct Option: C
Explanation:

Jock itch of the groin, caused by tinea cruris, is a fungal infection that affects the skin of genitals, inner thighs and buttocks. Jock itch causes an itchy, red and often ring-shaped rash in these warm and moist areas of the body.

Which of the following is not a water borne disease?

  1. Leptospirosis

  2. Hepatitis B

  3. Hepatitis A

  4. Poliomyelitis


Correct Option: B
Explanation:

Hepatitis B is acquired through blood to blood contact. Thus, it is not a water borne disease.

Zika fever vector is associated with

  1. malaria

  2. dengue

  3. filariasis

  4. lymphatic filariasis


Correct Option: B
Explanation:

The vector for Zika fever is Aedes mosquito. The same mosquito also transmits dengue fever.

Catatonia is a/an

  1. congenital disorder

  2. mental disorder

  3. blood disorder

  4. allergy


Correct Option: B
Explanation:

Catatonia is a mental disorder. It is a state of neurogenic motor immobility and behavioral abnormality that is manifested by stupor.

Which of the following diseases is manifested by ascending paralysis?

  1. Botulism

  2. REM sleep

  3. Guillain-Barré syndrome

  4. Anderson-Tawii syndrome


Correct Option: C
Explanation:

Guillain-Barré syndrome is manifested by ascending paralysis. It is also called Landry's ascending paralysis.

Which of the following diseases is on the verge of global eradication?

  1. Small pox

  2. Yaws

  3. Hookworm disease

  4. Lymphatic filariasis


Correct Option: B
Explanation:

Global eradication of yaws in underway. Yaws is a rarely fatal but highly disfiguring disease that is caused by spiral-shaped bacterium (Spirochete) Treponema pallidum pertenue. No cases have been seen in India since 2004 and hopefully, global elimination will be achieved by 2020.

Which of the following is the etiological agent of Creutzfeldt-Jakob disease?

  1. Virus

  2. Prion

  3. Viroid

  4. Mycoplasma


Correct Option: B
Explanation:

CJD is caused by an infectious agent called prion.

Cystic echinococcosis (cystic hydatid disease) is a tapeworm disease caused by

  1. Echinococcus multilocularis

  2. Echinococcus granulosus

  3. Echinococcus vogeli

  4. Echinococcus oligarthrus


Correct Option: B
Explanation:

Echinococcus granulosus causes cystic hydatid disease in humans.

Which of the following genetic disorders was previously known as Mongolian idiocy?

  1. Huntington's disease

  2. Down's syndrome

  3. Edward's syndrome

  4. Klinefelter syndrome


Correct Option: B
Explanation:

Down's syndrome is a genetic disorder caused by the presence of all, or part of, a third copy of chromosome 21. It was earlier known as Mongoloid idiocy.

Which of the following pairs is incorrectly matched?

  1. White plague - Tuberculosis

  2. Black plague - Bubonic plague

  3. American plague - Typhus fever

  4. Hansen's disease - Leprosy


Correct Option: C
Explanation:

This is incorrect. American plague is yellow fever.

Which of the following diseases in humans is caused by S. typhimurium?

  1. Typhoid

  2. Typhus fever

  3. Gastroenteritis

  4. Paratyphoid fever


Correct Option: C
Explanation:

S. typhimurium causes gastroenteritis in humans. When the bacterial cells enter epithelial cells lining the intestine, they cause host cell ruffling which temporarily damages the microvilli on the surface of the cell. This causes a rush of white blood cells into the mucosa, which throws off the ratios between absorption and secretion and leads to diarrhoea.

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