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Biology

Description: Important Macromolecules, Enzymes and Metabolites of life
Number of Questions: 15
Created by:
Tags: Science Chemical Reactions involving Enzymes Secondary Metabolites Lipids
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The enzyme associated with neutrophil granulocytes in human blood is called

  1. cytochrome c oxidase

  2. peroxidase

  3. myeloperoxidase

  4. guanylate cyclase

  5. colipase

Show answer
Correct Option: C
Explanation:

Myeloperoxidase is most abundantly expressed in neutrophil granulocytes.

Which of the following is the chief metabolite of bupropion?

  1. Hydroxybupropion

  2. Hydroxycarteolol

  3. Kynurenine

  4. 3-Methoxymorphinan

  5. Seproxetine

Show answer
Correct Option: A
Explanation:

Hydroxybupropion is the major active metabolite of the antidepressant and smoking cessation drug bupropion.

The enzyme cytochrome c oxidase is a large transmembrane protein complex found in bacteria and the mitochondrion of eukaryotes.

  1. Human brain cannot utilise fatty acids as an energy source.

  2. Liver cells can synthesise and store triglycerides.

  3. The triglycerides form chylomicrons.

  4. The process lipolysis takes place in the intestine.

  5. In triglyceride form, lipids cannot be absorbed by jejunum.

Show answer
Correct Option: E
Explanation:

In triglyceride form, lipids cannot be absorbed by the duodenum.

Which of the following statements does NOT characterise unsaturated fats?

  1. Meat products contain both saturated and unsaturated fats.

  2. Replacing saturated fats with unsaturated fats helps to lower the levels of total cholesterol in human beings.

  3. Unsaturated chains have a lower melting point.

  4. Unsaturated fats are popular with manufacturers of processed foods.

  5. Double bonds may be either in a cis or a trans isomer.

Show answer
Correct Option: D
Explanation:

Saturated fats are popular with manufacturers of processed foods.

The metabolite observed in a huge amount in the plasma and urine of people suffering from malignant melanoma is called

  1. carboxycyclophosphamide

  2. cysteinyldopa

  3. dehydroepiandrosterone sulphate

  4. desmethylsertraline

  5. desvenlafaxine

Show answer
Correct Option: B
Explanation:

Cysteinyldopa is a catecholamine. Excessive cysteinyldopa in plasma and urine has been linked to malignant melanoma.

The fatty acid having antimicrobial pesticide properties is called

  1. heptanoic acid

  2. caprylic acid

  3. nonanoic acid

  4. lauric acid

  5. tridecylic acid

Show answer
Correct Option: B
Explanation:

Caprylic acid is used commercially in the production of esters.

The fatty acid which forms the glycerides of human adipose tissue is

  1. hexanoic acid

  2. valeric acid

  3. butyric acid

  4. propanoic acid

  5. palmitoleic acid

Show answer
Correct Option: E
Explanation:

Palmitoleic acid is a common constituent of the glycerides of human adipose tissue.

The fatty acid found in seeds and nuts is called

  1. α-linolenic acid

  2. dihomo-γ-linolenic acid

  3. eicosapentaenoic acid

  4. linoleic acid

  5. gamma-linolenic acid

Show answer
Correct Option: A
Explanation:

α-Linolenic acid is an essential omega-3 fatty acid found in seeds, nuts and many common vegetable oils.

Which of the following is a precursor of lysine in the alpha-aminoadipate pathway?

  1. Saccharopine

  2. Allysine

  3. α-Aminoadipic acid

  4. α-Ketoadipic acid

  5. Isovaleryl-coenzyme A

Show answer
Correct Option: A
Explanation:

Saccharopine is an intermediate in the metabolism of amino acid lysine.

The amino acid which has a fat-dissolving effect is

  1. taurine

  2. ornithine

  3. methionine

  4. carnitine

  5. arginine

Show answer
Correct Option: C
Explanation:

Methionine plays an important role in the synthesis of other proteins.

The fatty acid found in cerebroside is called

  1. gamma-linolenic acid

  2. stearidonic acid

  3. α-linolenic acid

  4. lignoceric acid

  5. paullinic acid

Show answer
Correct Option: D
Explanation:

Lignoceric acid is a saturated fatty acid.

Which of the following statements regarding metabolites is INCORRECT?

  1. Alcohol is a primary metabolite.

  2. The metabolome forms a large network of metabolic reactions.

  3. The rate of degradation of a metabolite is an important determinant of the duration and intensity of its action.

  4. Some antibiotics use sceondary metabolites as precursors.

  5. A secondary metabolite has an important ecological function.

Show answer
Correct Option: D
Explanation:

Some antibiotics use primary metabolites as precursors.

Which of the following statements regrading enzyme catalysis is INCORRECT?

  1. The mechanism of enzyme catalysis is similar in principle to other types of chemical catalysis.

  2. Enzymes provide an alternative reaction route.

  3. The induced fit model proposes that the initial interaction between the enzyme and the substrate is very strong.

  4. The advantages of the induced fit mechanism arise due to the stabilising effect of strong enzyme binding.

  5. Saturated enzymes have a high affinity substrate binding capacity.

Show answer
Correct Option: C
Explanation:

The favoured model for the enzyme-substrate interaction is the induced fit model. This model proposes that the initial interaction between the enzyme and the substrate is relatively weak.

The pungent odour of sulphur compounds is called

  1. aldolase

  2. triose phosphate isomerase

  3. trypsin

  4. cellulase

  5. alliinase

Show answer
Correct Option: E
Explanation:

Alliinase is responsible for catalysing chemical reactions that produce the volatile chemicals that give odours and tear-inducing properties.

The active metabolite of paracetamol is

  1. benzoylecgonine

  2. AM404

  3. calcitroic acid

  4. ethanol

  5. methanol

Show answer
Correct Option: B
Explanation:

AM404 is an active metabolite of paracetamol.

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