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Viral Infections (Medical Entrance)

Description: Infections, Viral Infections
Number of Questions: 16
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Tags: Infections Viral Infections Viral Diseases
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In which of the following conditions is Kernig's sign observed?

  1. Infectious mononucleosis

  2. Hepatocellular carcinoma

  3. Aseptic meningitis

  4. Laryngeal papillomas


Correct Option: C
Explanation:

Kernig's sign is observed in Aseptic meningitis. Kernig's sign is  positive when the thigh is bent at the hip and knee at 90 degree angles, and subsequent extension in the knee is painful. Aseptic meningitis, or sterile meningitis, is a condition in which the layers lining the brain, meninges, become inflamed caused by Herpes simplex virus 2.

Which virus causes Progressive Multifocal Leukoencephalopathy?

  1. BK virus

  2. JC virus

  3. TBE virus

  4. B19 virus


Correct Option: B
Explanation:

Progressive Multifocal Leukoencephalopathy (PML) is a disease of the white matter of the brain, caused by JC (John Cunningham) virus infection that targets cells that make myelin - the material that insulates nerve cells (neurons).

Herpes simplex virus type 2 is associated with

  1. Herpes labialis

  2. Aseptic meningitis

  3. Kaposi sarcoma

  4. Herpes zoster


Correct Option: B
Explanation:

Herpes simplex virus type 2 is associated with Aseptic meningitis. It is an inflammation of the meninges (the membranes covering the brain and spinal cord) caused by viral infection.

Which virus was the main reason for the 2013-2015 epidemic in West Africa?

  1. Marburg virus

  2. Banna virus

  3. Ebola virus

  4. Lassa virus


Correct Option: C
Explanation:

Ebola virus was the cause of the 2013–2015 epidemic in West Africa, which resulted in at least 28,638 suspected cases and 11,315 confirmed deaths. It causes fatal hemorrhagic fever in humans and other mammals.

Which of the following viruses is transmitted by faecal-oral route?

  1. Hepatitis A (HAV)

  2. Hepatitis B (HBV)

  3. Hepatitis C (HCV)

  4. Hepatitis D (HDV)


Correct Option: A
Explanation:

Hepatitis A is transmitted by faecal-oral route and hence, causes acute hepatitis.

What is common among families Bunyaviridae, Togaviridae and Flaviviridae?

  1. Group IV virus

  2. Arthropod transmission

  3. Positive sense RNA virus

  4. Symptoms


Correct Option: B
Explanation:

Bunyavirus, Flavivirus and Togavirus are exclusively transmitted by arthropods.

Which virus is associated with Korean hemorrhagic fever in humans?

  1. Crimean-Congo hemorrhagic fever virus (CCHFV)

  2. Hantaan river virus

  3. Dobrava-Belgrade virus

  4. Sangassou virus


Correct Option: B
Explanation:

Hantaan river virus is the causative agent of Korean hemorrhagic fever in humans. Initial symptoms begin suddenly and include intense headaches, back and abdominal pain, fever, chills, nausea and blurred vision. Individuals may have flushing of the face, inflammation or redness of the eyes or a rash. Later symptoms can include low blood pressure, acute shock, vascular leakage and acute kidney failure, which can cause severe fluid overload.

Which of the following is not a risk group IV human pathogens?

  1. Alkhurma virus

  2. Junin virus

  3. Herpes B virus

  4. HIV virus


Correct Option: D
Explanation:

HIV virus does not belong to risk group IV human pathogens. Risk Group 4 (RG4) agents are likely to cause serious or lethal human disease for which preventive or therapeutic interventions are not usually available. HIV is a group II virus because for it, preventative or therapeutic interventions are often available.

Which serotype of parainfluenza virus is associated with bronchiolitis and pneumonia?

  1. HPIV-3

  2. HPIV-1

  3. HPIV-2

  4. HPIV-4


Correct Option: A
Explanation:

Human parainfluenza virus type 3 (HPIV-3) is associated with bronchiolitis and pneumonia.

Who discovered the polio virus?

  1. Salk and Sabin

  2. Karl Landsteiner and Erwin Popper

  3. Hilary Koprowski

  4. Robert Koch


Correct Option: B
Explanation:

Karl Landsteiner and Erwin Popper discovered poliovirus in 1908 by proving that it was not a bacterium that caused paralysis, but a much smaller entity - a virus.

Which of the following is/are the vector for the causative agent of yellow fever?

  1. Sandflies

  2. Triatomine bugs

  3. Aedes mosquito

  4. Culex mosquito


Correct Option: C
Explanation:

Yellow fever is caused by yellow fever virus, which is spread by the bite of female mosquito. It spreads primarily by Aedes aegypti mosquito.

______ is an enveloped causative agent of gastroenteritis.

  1. Bocavirus

  2. Norwalk virus

  3. Coronavirus

  4. Novovirus


Correct Option: C
Explanation:

Coronavirus is the only enveloped causative agent of gastroenteritis.

Which viral infection usually precedes Reye's syndrome?

  1. Herpes virus type 8

  2. Influenza virus

  3. Cytomegalovirus

  4. Papilloma virus


Correct Option: B
Explanation:

Reye's syndrome is a rapidly progressive encephalopathy, which usually begins shortly after recovery from an acute infection of influenza virus.

A childhood rash disease called fifth disease is associated with

  1. human bocavirus

  2. parvovirus B19

  3. rhinovirus

  4. TBE virus


Correct Option: B
Explanation:

Parvovirus B19 causes a childhood rash disease called fifth disease or erythema infectiosum, or slapped cheek syndrome. Symptoms are bright red rash of the cheeks, fever, diarrhea, nausea, exacerbation of rash by the sunlight, heat and stress.

The risk of Hodgkin's lymphoma increases in the presence of

  1. Coxsackievirus

  2. Epstein-Barr virus

  3. Adenovirus

  4. Lassa virus


Correct Option: B
Explanation:

The risk of Hodgkin's lymphoma increases in the presence of Epstein-Barr virus,  but the precise contribution of Epstein–Barr virus remains largely unknown. Epstein-Barr virus causes infectious mononucleosis. Both the diseases affect lymph nodes.

Match the members of family Reoviridae with the diseases they cause ||| |---|---| |Virus|Disease| |1. Colt virus|a. Encephalitis| |2. Orbo virus|b. Colorado tick fever| |3. Banna virus|c. Blue-tongue disease| |4. Rota virus|d. Diarrhoea|

  1. 1. Colt virus c. Blue tongue disease
    2. Orbo virus a. Encephalitis
    3. Banna virus d. Diarrhoea
    4. Rota virus b. Colorado tick fever
  2. 1. Colt virus d. Diarrhoea
    2. Orbo virus c. Blue tongue disease
    3. Banna virus b. Colorado tick fever
    4. Rota virus a. Encephalitis
  3. 1. Colt virus b. Colorado tick fever
    2. Orbo virus c. Blue tongue disease
    3. Banna virus a. Encephalitis
    4. Rota virus d. Diarrhoea
  4. 1. Colt virus a. Encephalitis
    2. Orbo virus d. Diarrhoea
    3. Banna virus b. Colorado tick fever
    4. Rota virus c. Blue tongue disease

Correct Option: C
Explanation:

This is the correct match. Colt virus causes Colorado tick fever, Orbivirus causes blue tongue disease in sheep, cattle, goats and wild ungulates, Banna virus causes encephalitis and Rota virus is associated with diarrhoea in children.

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