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Historical Perspective in Microbiology

Description: GATE: Life Science: Microbiology: Historical Perspective
Number of Questions: 20
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Tags: historical perspective microbiology Biology Quadratic Equations and Inequalities Mathematics Common Roots Complex Numbers and Quadratic Equations Transformations Argand Plane and Polar Representation
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Pure culture of bacteria was first obtained by ________.

Directions: Laboratory procedures have been developed that make it possible to isolate microorganisms representing each species and to grow each of the species separately.

  1. Joseph Lister

  2. Koch

  3. Bruce

  4. Ducrey

  5. Van Ermengem


Correct Option: A
Explanation:

Pure culture of bacteria was first obtained by Joseph Lister.

Who postulated that disease is produced by invisible living creatures?

  1. Ignaz Semmelweis

  2. Robert Koch

  3. Roger Bacon

  4. Walter Reed

  5. Paul Ehrlich


Correct Option: C
Explanation:

During the thirteenth century, Roger Bacon (1220-1292) postulated that disease is produced by invisible living creatures.

The principle of immunization was demonstrated by whom?

  1. Pasteur

  2. Roger Bacon

  3. Francesco Redi

  4. Spallanzani

  5. Joseph Lister


Correct Option: A
Explanation:

The principle of immunization was demonstrated by Pasteur.

Who wrote “The Contagiousness of Puerperal Fever in 1842”?

  1. Walter Reed

  2. Francesco Redi

  3. Joseph Lister

  4. Wendell Holmes

  5. Koch


Correct Option: D
Explanation:

He wrote “ The Contagiousness of Puerperal Fever in 1842.”

Who suggested that the animals might have originated spontaneously from the soil, plants or other dissimilar animals?

  1. Aristotle

  2. Virgil

  3. Francesco Redi

  4. John Nidham

  5. John Tyndall


Correct Option: A
Explanation:

He taught that animals originated spontaneously from soil, plants or other animals.

Who introduced complement-fixation test for syphilis?

  1. August von Wassermann

  2. Roger Bacon

  3. Francesco Redi

  4. Spallanzani

  5. Joseph Lister


Correct Option: A
Explanation:

He introduced complement-fixation test for syphilis.

What is an “antitoxin”?

Directions: Emil von Behring and Kitasato devised a method of producing immunity to infections caused by organisms by injecting their toxins into animals so that an antitoxin would develop.

  1. A substance that inhibits the action of toxin.

  2. A substance that enhances the action of toxin.

  3. A substance that helps the toxin to work.

  4. A substance that neutralizes toxin.

  5. It has nothing to do with toxin.


Correct Option: D
Explanation:

Antitoxin is a substance that neutralizes toxin.

Identify the person from the following options, who believed that animals might originate spontaneously from the soil, plants or other unlike animals:

  1. Aristotle

  2. Needham

  3. Spallanzani

  4. Schulze

  5. Aristotle, Needham and Spallanzani


Correct Option: E
Explanation:

Aristotle, Needham and  Spallanzani believed that animals might originate spontaneously from the soil, plants or other unlike animals.

Which of the following devices and procedures disproved the theory of spontaneous generation?

  1. Schwann heat sterilized the air which flowed through the glass tube to his culture flask.

  2. Schroder and von Dusch filtered the air entering the culture flask through cotton.

  3. Simple goose-necked flasks were devised by Pasteur.

  4. Tyndall constructed a dust-free incubation chamber.

  5. All of the above


Correct Option: E
Explanation:

All the above statements are true.

What is “plant pathology“?

Directions: Late in the 19th century, T.J. Burrill, working in Illinois, discovered the fire blight disease in pear caused by a bacterium. This opened a new area of microbiology called “ plant pathology”.

  1. The study of plant hormones.

  2. The study of plant diseases.

  3. The study of water transport in plants.

  4. The study of plant diversity and naming.

  5. The study of heredity in plants.


Correct Option: B
Explanation:

Plant pathology is the study of plant diseases.

Who was the first person to recognize the role of phagocytes in combating bacterial infections?

  1. Elie Metchnikoff

  2. Ignaz Semmelweis

  3. Bruce

  4. Walter Reed

  5. None of the above


Correct Option: A
Explanation:

He was the first person to recognize the role of phagocytes in combating bacterial infections.

What is a “toxin”?

  1. It is basically a poison that harms an organism.

  2. It is a secretion from the salivary gland.

  3. Its a humoral factor in blood.

  4. It is an anticoagulant.

  5. All of the above


Correct Option: A
Explanation:

A toxin is basically a poison that harms an organism.

Transmission of viral diseases of plants by insects was suggested by _________.

Directions: Late in the 19th century, T.J. Burrill, working in Illinois, discovered the fire blight disease in pear caused by a bacterium. This opened a new area of microbiology called “ plant pathology”.

  1. H. Weigmann

  2. Martinus Beijerinck

  3. A Japanese farmer Hashimoto

  4. Emil Hansen

  5. McCoy and Chapin


Correct Option: C
Explanation:

A Japanese farmer Hashimotom suggested the Transmission of viral diseases of plants by insects.

Match the following:

Disease Discoverer
A. Tuberculosis (i) Koch
B. Tetanus (ii) Bordet and Gengou
C. Dysentery (iii) Nicolaier
D. Whooping cough (iv) Shiga
  1. A - i, B - iii, C - iv, D - ii

  2. A - i, B - ii, C - iii, D - iv

  3. A - ii, B - i, C - iii, D - iv

  4. A - iii, B - iv, C - i, D - ii

  5. A - iv, B - iii, C - ii, D - i


Correct Option: A
Explanation:

Tuberculosis was discovered by Koch; Tetanus by Nicolaier; Dysentery by Shiga;  Whooping cough by Bordet and Gengou.

What is germ theory?

  1. It states that a disease-causing microorganism should be present in animals infected by the disease and not in healthy animals.

  2. It states that a disease-causing microorganism should be present in healthy animals and not in infected animals.

  3. It states that a disease-causing microorganism should be destroyed.

  4. It states that a disease-causing microorganism cannot be destroyed.

  5. Both 2 and 4 are correct.


Correct Option: A
Explanation:

Germ theory states that a disease-causing microorganism should be present in animals infected by the disease and not in healthy animals.

Who discovered diphtheria?

  1. Loeffler

  2. Koch

  3. Bruce

  4. Ducrey

  5. Van Ermengem


Correct Option: A
Explanation:

He discovered diphtheria.

Pasteurization of milk is done by __________.

  1. boiling the milk for 20 mins.

  2. heating the milk at 72oC for 30 mins.

  3. heating the milk at 72oC for 20 mins.

  4. heating the milk at 62oC for 30 mins.

  5. none of the above


Correct Option: D
Explanation:

This is correct.

The growth of a mass of cells of the same species in a test tube is called _________.

Directions: Laboratory procedures have been developed that make it possible to isolate microorganisms representing each species and to grow each of the species separately.

  1. sericulture

  2. pure culture

  3. apiculture

  4. pisciculture

  5. aquaculture


Correct Option: B
Explanation:

The growth of a mass of cells of the same species in a test tube is called pure culture.

Which branch of biology is referred here in the above statement?

Directions: The recent most dramatic development in applied microbiology is the ability to alter an organism’s genetic makeup.

  1. Physiology

  2. Ethology

  3. Genetic Engineering

  4. Ornithology

  5. Palaeontology


Correct Option: C
Explanation:

Genetic Engineering is the ability to alter an organism’s genetic makeup.

New pieces of DNA can be inserted into a DNA molecule in a process called __________.

Directions: The recent most dramatic development in applied microbiology is the ability to alter an organism’s genetic makeup.

  1. mutation

  2. recombination

  3. replication

  4. transcription

  5. translation


Correct Option: B
Explanation:

New pieces of DNA can be inserted into a DNA molecule in a process called recombination.

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