Immunology
Description: GATE: Life Sciences : Zoology : Immunology | |
Number of Questions: 20 | |
Created by: Amal Dixit | |
Tags: Immunology Biology |
Viral replication within cells is inhibited by _____ .
One molecule of secretory IgA can at most bind to _____.
Lack of thymus leads to increased infection in human such a condition is called ______.
In myasthenia gravis blocking antibody binds to ______.
Monoclonal antibodies differ from polyclonal antibodies in their property of reacting with _____.
Class switching takes place in ____ .
The T-cell receptors can bind to antigenic peptide ____ .
What is the function of C1 in the classical pathway of complement activation?
The tuberculin skin test is an example of _____.
Which one of the following acts as C3 convertase in this particular pathway?
The alternative pathway of complement activation is triggered when a breakdown product of C3 hydrolysis, C3b is deposited on the surface of a microbe. Next step in this pathway is to form C3 convertase which enzymatically breaks down more C3.
Hypoxanthine is also used for selecting the hybridomas based on the following: P. Only hybridoma will grow since, it inherited the HGPRT genes from B cells and can synthesize DNA from Hypoxanthine. Q. Myeloma cells wil not grow in culture since, de novo synthesis is blocked by aminopterin and due to lack of HGPRT enzyme.
In hybridoma technology for monoclonal Ab production antibiotic is used to select hybridoma cell over myeloma cells.
What is the type of interaction between this particular Ag with 4 epitopes and the IgG Ab?
In an antigen antibody interaction, in the zone of equivalence, the isolated antigen IgG complex was found to be in the molar ratio of Antigen : IgG = 2 : 1
Choose the correct match:
P. Eosinophil | 1. An antigen presenting cell that is not phagocytic. |
Q. Kuffer Cell | 2. Generally first cell to arrive at the site of inflammation. |
R. Dendrite Cell | 3. Macrophages found in liver. |
S. Mast Cell | 4. Phagocytic cell important in the body’s defense against parasitic organisms. |
5. Type I hypersensitivity. |
Match the two columns: column-I & column-II:
A. C4b2a | 1. Pentamer |
B. IgM | 2. ELISA |
C. B cell maturation | 3.C3 convertase |
D. Horse radish peroxidase | 4. Active immunization |
E. Vaccine | 5. Stromal cell |
Which one of the following antibiotic is used?
In hybridoma technology for monoclonal Ab production antibiotic is used to select hybridoma cell over myeloma cells.
What is toxoid?
Tetanus is a medical condition characterized by a prolonged contraction of skeletal muscle fibre and caused by bacterium Clostridium tetani. Toxoid is used in order to prevent neonatal tetanus.
Choose the correct match:
Group-I | |
Group-II | |
P. Natural killer cell | 1. Express CD4 receptor |
Q. Helper T cell | 2. Express CD8 receptor |
R. Cytotoxic T cell | 3. Express CD16 receptor |
S. Macrophages | 4. Express surface IgD molecule |
5. Express KIR |
Which of the following compound stabilize C3 convertase in this alternative pathway?
The alternative pathway of complement activation is triggered when a breakdown product of C3 hydrolysis, C3b is deposited on the surface of a microbe. Next step in this pathway is to form C3 convertase which enzymatically breaks down more C3.
The number of epitope(s) present on the antigen is _____.
In an antigen antibody interaction, in the zone of equivalence, the isolated antigen IgG complex was found to be in the molar ratio of Antigen : IgG = 2 : 1
Which of the following treatment procedure is used to administer toxoid?
Tetanus is a medical condition characterized by a prolonged contraction of skeletal muscle fibre and caused by bacterium Clostridium tetani. Toxoid is used in order to prevent neonatal tetanus.