0

Golgi Apparatus (Medical Entrance)

Description: Proteins
Number of Questions: 15
Created by:
Tags: golgi apparatus Golgi Bodies/Dictyosomes Endomembrane System of Cell
Attempted 0/15 Correct 0 Score 0

Which filaments play a critical role in vacuolar trafficking at the Golgi complex in plant cells?

  1. Intermediate filaments

  2. Microtubules

  3. Actin filaments

  4. FtsZ


Correct Option: C
Explanation:

Actin filaments play a critical role in vacuolar trafficking at the Golgi complex in plant cells.

The cis golgi network originates from

  1. vacuoles

  2. endoplasmic reticulum

  3. lysosomes

  4. nuclear membrane


Correct Option: B
Explanation:

The cis golgi network originates from vesicular clusters that bud off the endoplasmic reticulum.

Which of the following processes takes place in cis-cisterna with the cargo proteins?

  1. Removal of mannose residues and addition of N-acetylglucosamine

  2. Addition of galactose and sialic acid

  3. Removal of mannose residues

  4. Sulfation of tyrosines and carbohydrates


Correct Option: C
Explanation:

Cis cisterna are associated with the removal of mannose residues. Apart from it, phosphorylation of oligosaccharides on lysosomal proteins occurs in the early CGN.

Which type of vesicles carry antibodies?

  1. Vacuoles

  2. Exocytotic vesicles

  3. Secretory vesicles

  4. Lysosomal vesicles


Correct Option: B
Explanation:

Antibodies are carried by exocytotic vesicle. These vesicles contain proteins destined for extracellular release. After packaging, the vesicles bud off and immediately move towards the plasma membrane, where they fuse and release the contents into the extracellular space.

Where are the vesicles that leave the rough ER transported?

  1. Trans face of golgi

  2. Cis face of golgi

  3. Cisternae

  4. Secretory vesicle


Correct Option: B
Explanation:

The vesicles that leave the rough ER are transported to cis face of golgi.

Which of the following are a product of regulated secretion?

  1. Digestive proteases

  2. Antibodies

  3. Neurotransmitters

  4. Membrane proteins


Correct Option: C
Explanation:

Neurotransmitters are released by the process of regulated secretion. The vesicles carrying neurotransmitters fuse with membrane and release their contents once an appropriate signal is received.

COPII coated vesicles are responsible for trafficking between

  1. Golgi and Plasma Membrane

  2. Golgi and ER (retrograde transport)

  3. ER and Golgi (anterograde transport)

  4. Golgi and Endosomes


Correct Option: C
Explanation:

COPII coated vesicles are responsible for anterograde transport from the ER to the Golgi.

GERL region of Golgi has high activity of

  1. G-protein

  2. acid phosphatase

  3. cytidine monophosphate

  4. lead phosphate


Correct Option: B
Explanation:

GERL region of Golgi has high activity of acid phosphatase.

Where do the enzymatic reactions occur within Golgi apparatus?

  1. In the lumen

  2. Near the membrane surface where enzymes are anchored

  3. In lysosomes

  4. In secretory vesicles


Correct Option: B
Explanation:

Enzymatic reactions within the Golgi stacks occur exclusively near its membrane surfaces, where enzymes are anchored.

Which fungal metabolite disrupts the structure and function of Golgi apparatus?

  1. L-741,494

  2. Brefeldin A

  3. Ciclosporin

  4. Fumonisin


Correct Option: B
Explanation:

Brefeldin A (BFA) is a fungal metabolite which disrupts the structure and function of the Golgi apparatus by inhibiting transport of proteins from ER to Golgi and inducing retrograde protein transport from the Golgi apparatus to the endoplasmic reticulum.

Which of the following models is the most accepted model to explain vesicular traffic throughout the Golgi apparatus?

  1. Anterograde vesicular transport between stable compartments model

  2. Cisternal progression/maturation model

  3. Cisternal progression/maturation with heterotypic tubular transport model

  4. Rapid partitioning in a mixed Golgi model


Correct Option: B
Explanation:

This is the most accepted model by scientists. According to this model, the transport of cargo proteins through the Golgi complex occurs by the progression of cisternae from the cis face to the trans face of the Golgi stack. Each cisterna changes its position in the stack repeatedly until it reaches the trans face. Thus, the cisternae themselves act as carriers in this intra-Golgi trafficking segment.

Golgi bodies were discovered in

  1. blood cell

  2. nerve cell

  3. skin cell

  4. plant cell


Correct Option: B
Explanation:

Golgi body was discovered in 1898 by Italian physician Camillo Golgi during an investigation of the nervous system, i.e. nerve cells.

Where is the Golgi apparatus localized in a mammalian cell?

  1. Scattered through the cytoplasm

  2. Close to centrosome

  3. Adjacent to mitochondria

  4. Attached to the cell membrane


Correct Option: B
Explanation:

In mammals, a single Golgi apparatus complex is usually located near the cell nucleus, close to the centrosome.

Match the columns:

 
Column A Column B
1. Pichia pastoris a. Unstacked golgi
2. Saccharomyces b. Stacked golgi
3. CGN c. Endosome
4. TGN d. Cisternae
  1.  
    1. Pichia pastoris d. Endosome
    2. Saccharomyces b. Stacked golgi
    3. CGN c. Endosome
    4. TGN a. Unstacked golgi
  2.  
    1. Pichia pastoris b. Stacked golgi
    2. Saccharomyces a. Unstacked golgi
    3. CGN d. Cisternae
    4. TGN c. Endosome
  3.  
    1. Pichia pastoris d. Cisternae
    2. Saccharomyces c. Endosome
    3. CGN b. Stacked golgi
    4. TGN a. Unstacked golgi
  4.  
    1. Pichia pastoris c. Endosome
    2. Saccharomyces b. Stacked golgi
    3. CGN d.Cisternae
    4. TGN a. Unstacked golgi

Correct Option: B
Explanation:

This is correct pairing. Pichia pastoris have stacked golgi, Saccharomyces have unstacked golgi, CGN s a collection of fused, flattened membrane-enclosed disks known as cisternae and TGN may act as an early endosome in yeast and plants.

Besides secretory functions, Golgi apparatus is also involved in the formation of

  1. lysosomes and vacuoles

  2. lysosomes and endoplasmic reticulum

  3. lysosomes and proteoglycans

  4. glycosaminoglycans and vacuoles


Correct Option: C
Explanation:

Golgi apparatus is involved in the formation of lysosomes and proteoglycans.

- Hide questions